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한국학술지인용색인(NRF)
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Background: The purpose of this study was to compare the postoperative analgesic effects and side effects of an intra-articular PCA infusion of bupivacaine and morphine using an intravenous PCA infusion of morphine following arthroscopic shoulder surgery.
Methods: Seventy-one patients, undergoing arthroscopic shoulder surgery under general anesthesia, were randomly assigned to one of two groups. In group 1 (n = 32), morphine and ondansetron, 8 and 4 mg, respectively, were intravenously injected following surgery, with the subsequent infusion of normal saline 100 ml, including morphine and ondansetron, 32 and 12 mg, respectively, through an intra-venous PCA catheter. In group 2 (n = 39), 0.25% bupivacaine, 40 ml, including an intra-articular injection of morphine, 3 mg, followed by an infusion of 0.25% bupivacaine, 100 ml, including morphine, 5 mg, were administered through an intra-articular PCA catheter. In groups 1 and 2, the PCA infusion rate was 2 ml/h, with a bolus dose of 0.5 ml, with a lock out time of 8 min. The VAS for pain at rest, and the range of motion (ROM) exercise and side effects were assessed 0.5, 1, 2, 4, 12, 18 and 24 h postoperatively.
Results: The patients in group 2 had significantly lower VAS for pain for the ROM than those in group 1 30 min postoperatively. However, the VAS for pain at rest was significantly lower in group 1 than 2 after 18 and 24 h, but the VAS for pain for the ROM was significantly lower in group 1 than 2 24 h postoperatively. There was no significant difference in the side effects between the two groups, with the exception of dizziness, which was more severe in group 2 at 1, 2 and 4 h postoperatively.
Conclusions: An intra-articular PCA infusion of bupivacaine and morphine is no more effective than an intra-venous PCA infusion of morphine and ondansetron with respect to postoperative analgesia and side effects.권호기사
참고문헌 (34건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Interscalene block anesthesia for shoulder surgery.  |
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| 2 | Postoperative analgesia after major shoulder surgery with interscalene brachial plexus blockade, | 미소장 |
| 3 | Interscalene brachial plexus block anesthesia for the modified Bristow procedure. |
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| 4 | (1997) Suprascapular nerve block for postoperative pain relief in arthroscopic shoulder surgery: a new modality? , | 미소장 |
| 5 | Involvement of capsaicin-sensitive neurones in hyperalgesia and enhanced opioid antinociception in inflammation. |
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| 6 | Opioids from Immunocytes Interact with Receptors on Sensory nerves to Inhibit Nociception in Inflammation |
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| 7 | Intraarticular Analgesia Following Knee Arthroscopy |
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| 8 | Subacromial and intra-articular morphine versus bupivacaine after shoulder arthroscopy |
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| 9 | (1999) Comparison of the analgesic effects of intrabursal oxycodone and bupivacaine after acromioplasty, | 미소장 |
| 10 | (2004) Pain relief after arthroscopic shoulder surgery: a comparison of intraarticular analgesia, suprascapular nerve block, and interscalene brachial plexus block, | 미소장 |
| 11 | (2000) The pain control infusion pump for postoperative pain control in shoulder surgery, | 미소장 |
| 12 | (2002) The efficacy of continuous intrabursal infusion with morphine and bupivacaine for postoperative analgesia after subacromial arthroscopy, | 미소장 |
| 13 | (2001) The effect of continuous intra-articular and intra-bursal infusion of lidocaine on postoperative pain following shoulder arthroscopic surgery. Masui 2001, | 미소장 |
| 14 | (2003) Patient-controlled regional analgesia (PCRA) with ropivacaine after arthroscopic subacromial decompression, | 미소장 |
| 15 | Intra-articular morphine for the management of frozen shoulder. |
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| 16 | (1999) Wound infiltration and drain lavage with ropivacaine after major shoulder surgery, | 미소장 |
| 17 | Opioid peptides selective for mu- and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance |
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| 18 | Activation of mu opioid receptors inhibits transient high- and low-threshold Ca2 currents, | 미소장 |
| 19 | Opioids suppress spontaneous activity of polymodal nociceptors in rat paw skin induced by ultraviolet irradiation |
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| 20 | Opiates inhibit the discharges of fine afferent units from inflamed knee joint of the cat |
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| 21 | Substance P release from knee joint afferent terminals modulation by opioids. Brain Res 1988, | 미소장 |
| 22 | an evaluation of their peripheral actions in inflammation. Med Res Rev 1992, | 미소장 |
| 23 | Interleukin 1β and Corticotropin-Releasing Factor Inhibit Pain by Releasing Opioids from Immune Cells in Inflamed Tissue |
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| 24 | Peripheral mechanisms of opioid antinociception in inflammation: involvement of cytokines |
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| 25 | Postarthroscopy Analgesia with Intraarticular Bupivacaine/Morphine |
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| 26 | Comparison of postoperative analgesic effects of intraarticular bupivacaine and morphine following arthroscopic knee surgery. |
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| 27 | (2000) Patient-controlled lidocaine analgesia for acromioplasty surgery, | 미소장 |
| 28 | (2004) Continuous subacromial bupivacaine infusion for postoperative analgesia after open acromioplasty and rotator cuff repair: preliminary results, | 미소장 |
| 29 | pharmacokinetics and analgesic plasma concentrations of morphine. Clin Pharmacokinet 1982, | 미소장 |
| 30 | Measurement and control of postoperative pain. Ann R Coll Surg Engl 1979 Intra-articular morphine for pain relief after knee arthroscopy. J Bone Joint Surg Br 1992, | 미소장 |
| 31 | The efficacy of intra-articular morphine for postoperative knee arthroscopy analgesia |
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| 32 | Influence of alprazolam on opioid analgesia and side effects during steady-state morphine infusions |
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| 33 | Blood levels of bupivacaine after arthroscopy of the knee joint |
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| 34 | Serum bupivacaine concentrations after intraarticular injection for pain relief after knee arthroscopy |
미소장 |
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