본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

초록보기

Background : Renal cell carcinoma (RCC) is notorious for its high metastatic potential, and

30% of RCC patients present with metastatic disease at the initial presentation and 50% of

them will develop metastasis or recurrence after radical surgery. Methods : In an attempt to

identify the best predictive marker(s) for metastasis in patients with clear cell RCCs (CRCCs),

we examined the expression patterns of 7 metastasis/prognosis-related markers by constructing

a tissue microarray including primary CRCC specimens from 30 metastatic and 60 nonmetastatic

CRCCs. The markers we studied were Ki-67, MUC1, CD44s, PTEN, gelsolin, CA9

and p53. Results : The expressions of Ki-67, PTEN, CD44s, gelsolin and p53 were increased,

whereas those of MUC1 and CA9 were decreased in the metastatic CRCCs compared with

the non-metastatic CRCCs. The receiver operating characteristic curve-area under the curve

(AUC) value of Ki-67 was 0.671, which was the highest among the 7 markers. The optimal

cut-off value, sensitivity and specificity of the Ki-67 expression were 1.67%, 86.7% and 41.7%,

respectively. Conclusions : These results demonstrate that the Ki-67 expression was increased

in metastatic CRCCs, and it had the highest predictive value among the 7 markers. This suggests

that Ki-67 could be an excellent predictive marker for metastasis in CRCC patients.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
The expression of G1-S cell cycle inhibitors in normal placenta and gestational trophoblastic diseases Yan Hua Xuan ;Kyung Hee Kim ;Yoon-la Choi ;Geung-hwan Ahn ;Seoung Wan Chae ;Ho-chang Lee ;Ok-jun Lee pp.67-74

Correlation between cyclooxygenase-2 expression and HuR cytoplasmic translocation of breast cancer Sung-im Do ;In-gu Do ;Gou Young Kim ;Sun Lee ;Youn-wha Kim ;Yong-koo Park ;Juhie Lee ;Sung-jig Lim pp.75-80

Immunohistochemical markers for metastasis in clear cell renal cell carcinoma Kyungeun Kim ;Cheryn Song ;Jae Y. Ro ;Hanjong Ahn ;Yong Mee Cho pp.81-86

A multiinstitutional consensus study on the pathologic diagnosis of endometrial hyperplasia and carcinoma Kwang-sun Suh ;Insun Kim ;Moon Hyang Park ;Geung Hwan Ahn ;Jin Hee Sohn ;In Ae Park ;Hye Kyoung Yoon pp.87-93

비소세포암종의 epidermal growth factor receptor 발현과 EGFR 돌연변이와의 관계 석상희 ;김미진 pp.94-99

Secondary oxalosis involving the epididymis Sangkyum Kim ;Kwanggil Lee ;Namhoon Cho pp.100-102

Diffuse embryoma of the testis :a case report Won Ae Lee pp.103-107

Sarcoidosis associated with adenocarcinoma of the lung :a case report Joon Seon Song ;Seungkoo Lee ;Yong Hee Kim ;Se Jin Jang pp.108-112

A positive hybrid (HMW-CK and E-cadherin) carcinoma in situ arising in a phyllodes tumor of the breast :a case report Yun Kyung Kang ;Young Hyeh Ko pp.113-117

Chronic sclerosing dacryoadenitis :report of 2 cases Ji Eun Kwon ;Sang Kyum Kim ;Sang-ryul Lee ;Woo-ick Yang ;Haeryoung Kim pp.118-122

Adenomyoma of endocervical type in a first-trimester gravid uterine corpus :a brief report Hyunchul Kim ;Hoiseon Jeong ;Sangho Lee ;Young Seok Lee ;Bong Kyung Shin ;Insun Kim pp.123-124

Solitary pulmonary lymphangioma in an adult :a brief case report Hye-jong Song ;Joungho Han ;Kwhanmien Kim ;Kyung Soo Lee ;Jinwon Seo pp.125-127

Ectopic liver associated with the gallbladder :a brief case report Hee-eun Kyeong ;Younghee Park ;Sanghui Park pp.128-130

참고문헌 (25건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Cancer Statistics, 2007 네이버 미소장
2 Renal Cell Carcinoma: Management of Advanced Disease 네이버 미소장
3 Surveillance After Radical or Partial Nephrectomy for Localized Renal Cell Carcinoma and Management of Recurrent Disease 네이버 미소장
4 Results of Treatment of 255 Patients With Metastatic Renal Cell Carcinoma Who Received High-Dose Recombinant Interleukin-2 Therapy 네이버 미소장
5 CA9 gene expression in conventional renal cell carcinoma: a potential marker for prediction of early metastasis after nephrectomy. Clin Exp Metastasis 2007; 24:149-55. 미소장
6 AJCC cancer staging manual. 6th ed. New York: Springer-Verlag; 2002. pp. 323-328. 미소장
7 World Health Organization classofication of tumors. Lyon: IARC Press, 2004; 10-87. 미소장
8 Prognostic significance of morphologic parameters in renal cell carcinoma 네이버 미소장
9 Stratification of risk factors in renal cell carcinoma. 네이버 미소장
10 Role of molecular markers in the diagnosis and therapy of renal cell carcinoma 네이버 미소장
11 Using Tumor Markers to Predict Survival of Patients With Metastatic Renal Cell Carcinoma 네이버 미소장
12 A SCORING ALGORITHM TO PREDICT SURVIVAL FOR PATIENTS WITH METASTATIC CLEAR CELL RENAL CELL CARCINOMA: A STRATIFICATION TOOL FOR PROSPECTIVE CLINICAL TRIALS 네이버 미소장
13 Using Protein Expressions to Predict Survival in Clear Cell Renal Carcinoma 네이버 미소장
14 p53 is Independent Predictor of Tumor Recurrence and Progression After Nephrectomy in Patients With Localized Renal Cell Carcinoma 네이버 미소장
15 Expression of MUCI mucins inversely correlated with post-surgical survival of renal cell carcinoma patients. Br ] Cancer 1999; 80: 301-8. 미소장
16 Prognostic value of ploidy and proliferation markers in renal cell carcinoma 네이버 미소장
17 Correlation of Ki-67 and gelsolin expression to clinical outcome in renal clear cell carcinoma 네이버 미소장
18 MUC1 in carcinoma-host interactions.Glycoconj J 2000; 17:649-58. 미소장
19 Absence of correlation of MUCI expression to malignant behavior of renal cell carcinoma in experimental systems. Clin Exp Metastasis 2000; 18: 77-81. 미소장
20 The L1 Cell Adhesion Molecule Is Induced in Renal Cancer Cells and Correlates with Metastasis in Clear Cell Carcinomas 네이버 미소장
21 Caveolin-1 overexpression predicts poor disease-free survival of patients with clinically confined renal cell carcinoma. 네이버 미소장
22 Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study 네이버 미소장
23 Clear Cell Renal Cell Carcinoma: Gene Expression Analyses Identify a Potential Signature for Tumor Aggressiveness 네이버 미소장
24 Immunohistochemical analysis of tumor polyamines discriminates high-risk patients undergoing nephrectomy for renal cell carcinoma 네이버 미소장
25 Tumor B7-H1 Is Associated with Poor Prognosis in Renal Cell Carcinoma Patients with Long-term Follow-up 네이버 미소장

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기