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| 대표형(전거형, Authority) | 생물정보 | 이형(異形, Variant) | 소속 | 직위 | 직업 | 활동분야 | 주기 | 서지 | |
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The purpose of this study is to characterize canine mesenchymal stem cells (MSCs) derived from bone
marrow (BM) for use in research on the applications of stem cells in canine models of development, physiology, and
disease. BM was harvested antemortem by aspiration from the greater tubercle of the humerus of 30 normal beagle
dogs. Canine BM-derived MSCs were isolated according to methods developed for other species and were characterized
based on their morphology, growth traits, cell-surface antigen profiles, differentiation repertoire, immunocytochemistry
results, and neurotrophic factor expression in vitro. The canine MSCs exhibited a fibroblast-like morphology with a
polygonal or spindle-shaped appearance and long processes; further, their cell-surface antigen profiles were similar
to those of their counterparts in other species such as rodents and humans. The canine MSCs could differentiate into
osteocytes and neurons on incubation with appropriate induction media. RT-PCR analysis revealed that these cells
expressed NGF, bFGF, SDF-1, and VEGF. This study demonstrated that isolating canine MSCs from BM, stem-cell
technology can be applied to a large variety of organ dysfunctions caused by degenerative diseases and injuries in
dogs. Furthermore, our results indicated that canine MSCs constitutively secrete endogenous factors that enhance
neurogenesis and angiogenesis. Therefore, these cells are potentially useful for treating dogs affected with various
neurodegenerative diseases and spinal-cord injuries.| 기사명 | 저자명 | 페이지 | 원문 | 목차 |
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| Evaluation for serological patterns and fecal viral shedding by hemagglutination inhibition test and real-time PCR in Korean CPV-2 isolates | Hyeong-Sun Moon ;Joon-Seok Lee ;So-Jeong Nam ;Soon-Seek Yoon ;Moon-Il Kang ;Seok-Yong Jeoung ;Doo Ki | pp.435-439 |
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| Effect of methylprednisolone sodium succinate on innate immune function of canine peripheral blood phagocytes | Moo-Rim Park ;Ji-Houn Kang ;Mhan-Pyo Yang | pp.440-446 |
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| PCR based detection of Helicobacter spp. in saliva, dental plaque, vomitus and feces of dogs | Sung-Woo Ha ;Jong-Hyun Yoo ;Tae-Ho Chung ;Woo-Sung Jung ;Hwa-Young Youn ;Joon-Seok Chae ;Cheol-Yong | pp.447-451 |
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| Effects of chitosan on kidney function in streptozotocin-induced diabetic mice | Kwang-Won Sun ;Oh-Deog Kwon | pp.452-457 |
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| Canine mesenchymal stem cells derived from bone marrow :isolation, characterization, multidifferentiation, and neurotrophic factor expression in vitro | Dong-In Jung ;Jeongim Ha ;Ju-Won Kim ;Byeong-Teck Kang ;Jong-Hyun Yoo ;Chul Park ;Jong-Hwan Lee ;Hee | pp.458-465 |
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| Effects of petrolatum and glycerin on acetone damaged canine skin barrier | Won-Seok Oh ;Tae-Ho Oh | pp.466-470 |
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| Therapeutic effect of aquapuncture with bee-venom for canine pyoderma | Hyung-Kyou Jun ;Sang-Hun Kim ;Cristopher-Mun-Ho Kim ;Sung-Whan Cho ;Moo-Hyung Jun ;Myung-Jo You ;Duc | pp.471-475 |
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| Clinical and clinicopathological findings of naturally occurring hyperadrenocorticism in dogs :a retrospective study of 17 cases | Sang-Gil Kang ;Jong-Hyun Yoo ;Chul Park ;Hee-Myung Park | pp.476-481 |
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| Ophthalmic findings in 547 Korean sapsaree dogs | Je-Min Chae ;Won-Tae Kim ;Man-Bok Jeong ;Na-Young Yi ;Shin-Ae Park ;Se-Eun Kim ;Young-Woo Park ;Ji-H | pp.482-487 |
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| Effects of injectable anesthetics on fluorescein retinal angiographic phases in dogs | Jae-Young Jang ;Young-Sam Kim ;Won-Tae Kim ;Chang-Su Jung ;Hyun-Ah Kim ;Min-Su Kim ;Na-Young Yi ;Man | pp.488-493 |
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| The effects of hyaluronic acid-carboxymethylcellulose membrane (GUARDIX-MB^® ^) barriers on prevention of post-operation peritoneal adhesions in dogs | Sang-Mook Lee ;Hwan-Soo Jang ;Jae-Sung Bae ;Jung-Eun Kim ;Kwang-Ho Jang | pp.494-500 |
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| Estimation of gestational age by measurement of fetal and extra-fetal structures in Miniature Schnauzer bitches | Bang-Sil Kim ;Chang-Ho Son | pp.501-505 |
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| Bilateral congenital deafness in a white bull terrier :brainstem auditory evoked response findings | Byeong-Teck Kang ;So-Young Lee ;Dong-In Jung ;Hyung-Joong Kim ;Eung-Je Woo ;Hee-Myung Park | pp.506-509 |
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| Acute hepatic failure induced by xylitol toxicosis in two dogs | Chae-Young Lim ;Jong-Hyun Yoo ;Chun-Geun Kim ;Chul Park ;Hee-Myung Park | pp.510-513 |
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| Long-term chemotherapy with hydroxyurea in a dog with suspected intracranial meningioma | Dong-In Jung ;Chae-Young Lim ;Byeong-Teck Kang ;Ju-Won Kim ;Jong-Hyun Yoo ;Hee-Myung Park | pp.514-517 |
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| Cor triatriatum sinistrum with an ostium primum atrial septal defect in a siamese cat | Ran Choi ;Changbaig Hyun | pp.518-522 |
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| Sertoli cell tumor accompanied by pancytopenia in a dog | Ul-Soo Choi ;Hyun-Wook Kim ;Ji-Hye Choi ;Hye-Jin Kim ;Jae-Young Jang ;Chang-Woo Lee | pp.523-525 |
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| Alternative treatment for facial nerve paralysis in a dog | Hassan Abdel-Rahman Abdel-Rahman ;Hyung-Kyou Jun ;Kun-Ho Song ;Jun-Gu Kang ;Duck-Hwan Kim | pp.526-528 |
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| Duration of regain of deep pain perception after decompression surgery as a parameter of surgical outcome for acute thoracolumbar disc herniation hansen type Ⅰ with loss of deep pain perception in dogs | Sung-Su Park ;Ji-Hey Lim ;Ye-Eun Byeon ;Byung-Jun Jang ;Hak-Hyun Ryu ;Ji-Yong Uhm ;Byung-Jae Kang ;W | pp.529-532 |
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| Carnassial abscess following cellulitis complication in a young Maltese | Joong-Hyun Kim ;Kirae Cho ;Tae Sung Han ;Seong Soo Kang ;Gonhyung Kim ;Seok Hwa Choi | pp.533-536 |
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| Ununited anconeal process in a labrador retriever dog | Jae-Hoon Lee ;Wo-Jong Yang ;Eun-Hee Kang ;Hwa-Seok Chang ;Dai-Jung Chung ;Chi-Bong Choi ;Jeong-Ik Le | pp.537-539 |
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| Belt loop and circumcostal gastropexy techniques of canine gastric dilatation-volvulus :4 cases | Jae-Hoon Lee ;Young-Su Lee ;Wo-Jong Yang ;Dai-Jung Chung ;Eun-Hee Kang ;Hwa-Seok Chang ;Chi-Bong Cho | pp.540-544 |
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| Surgical reconstruction of the severe tongue laceration with mandibular fracture in a Siberian Husky dog | Jae-Hoon Lee ;Tae-Hoon Kim ;Wo-Jong Yang ;Eun-Hee Kang ;Hwa-Seok Chang ;Dai-Jung Chung ;Chi-Bong Cho | pp.545-548 |
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| Ileocecocolic and colocolic intussusception in a young Jindo | Joo-Hyun Jung ;Woong-Joo Chae ;Do-Hyoung Kwon ;Jin-Hwa Chang ;Sun-Kyoung Oh ;Jung-Hee Yoon ;Min-Cheo | pp.549-552 |
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| Radiographic features of traumatically caused retroflexion of urinary bladder in two dogs | Haebeom Lee ;Hyewon Kang ;Min-su Kim ;Namsoo Kim ;Kichang Lee | pp.553-556 |
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| Radiographic diagnosis of hypospadias in three Korean native calves | Won-Seok Jeong ;Yun-Sang Seong ;In-Su Kim ;Hwan-Soo Jang ;Tae-Ho Oh ;Keun-Woo Lee ;Kwang-Ho Jang | pp.557-559 |
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| 번호 | 참고문헌 | 국회도서관 소장유무 |
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| 1 | Use of alkaline phosphatase staining to differentiate canine osteosarcoma from other vimentin-positive tumors. ![]() |
미소장 |
| 2 | Choi BH, Huh JY, Park DJ, Kim BY, Lee SHR, Park SY. Differentiation of adult canine bone marrow stem cells into neurons. J Kor Oral Maxillofac Surg 2003; 29: 1-4. | 미소장 |
| 3 | Analysis of neuron-like differentiation of human bone marrow mesenchymal stem cells ![]() |
미소장 |
| 4 | In Vitro Differentiation of Human Marrow Stromal Cells into Early Progenitors of Neural Cells by Conditions That Increase Intracellular Cyclic AMP ![]() |
미소장 |
| 5 | A new molecular role for iron in regulation of cell cycling and differentiation of HL-60 human leukemia cells: iron is required for transcription of p21(WAF1/CIP1) in cells induced by phorbol myristate acetate. ![]() |
미소장 |
| 6 | Kadiyala S, Young RG, Thiede MA, Brauder SP. Culture expanded canine mesenchymal stem cells possess osteo-6: 125-134. | 미소장 |
| 7 | Expression of neural markers on bone marrow-derived canine mesenchymal stem cells. ![]() |
미소장 |
| 8 | Autologous adipose tissue-derived stromal cells for treatment of spinal cord injury. ![]() |
미소장 |
| 9 | Differentiating characterization of human umbilical cord blood-derived mesenchymal stem cells in vitro ![]() |
미소장 |
| 10 | Differentiation of functional dendritic cells and macrophages from human peripheral blood monocyte precursors is dependent on expression of p21 (WAF1/CIP1) and requires iron. ![]() |
미소장 |
| 11 | Mesenchymal Stem Cells and Bone Regeneration ![]() |
미소장 |
| 12 | Differentiation and isolation of hepatic-like cells from human embryonic stem cells ![]() |
미소장 |
| 13 | Neural differentiation of human mesenchymal stem cells: Evidence for expression of neural markers and eag K+ channel types. ![]() |
미소장 |
| 14 | Isolation and characterization of multipotential mesenchymal stem cells from feline bone marrow. ![]() |
미소장 |
| 15 | In vitro neuronal and osteogenic differentiation of mesenchymal stem cells from human umbilical cord blood. | 소장 |
| 16 | Quantification of bone alkaline phosphatase in canine serum. ![]() |
미소장 |
| 17 | Intracerebral peripheral blood stem cell (CD34+) implantation induces neuroplasticity by enhancing beta1 integrin-mediated angiogenesis in chronic stroke rats. ![]() |
미소장 |
| 18 | Effects of osteogenic inducers on cultures of canine mesenchymal stem cells. ![]() |
미소장 |
| 19 | Adult rat and human bone marrow stromal cells differentiate into neurons ![]() |
미소장 |
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