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Scutellaria radix (SR) has been utilized as a traditional medicine for a variety of diseases including Rheumatoid
arthritis and its major flavonoids - baicalein, baicalin, and wogonin - have been reported to exert beneficial health effects,
including anti-bacterial, anti-viral, anti-inflammatory, and free-radical scavenging. However, the mechanisms underlying this
effect remain poorly understood. The principal objective of this study was to determine the effect of SR on osteoblast and
osteoclast cells. SR extract was prepared using 70% ethanol solvent. Osteoblastic MC3T3-E1 cells and osteoclast precursor
Raw 264.7 macrophage cells were utilized. SR extract increased MC3T3-E1 cell proliferation and stimulated alkaline
phosphatase activity dose-dependently, 152.0% of the control at concentration 1 μg/mL. Additionally, SR extract (1 μg/mL)
stimulated Bone nodule formation activity in MC3T3-E1 cells, approximately 223.3% of the control, 20 days after the
exposure. In addition, SR extract significantly reduced the number of tartrate-resistant acid phosphatase-positive (TRAP+)
multinucleated cells from Raw 264.7 cells. In conclusion, SR extract stimulates the proliferation and bioactivities of boneforming
osteoblasts, and inhibits the activities of bone-resorbing osteoclasts to a certain degree.권호기사
참고문헌 (32건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Canalis E, (1988) Centrella M. Growth factors and the regulation of bone remodeling, J. Clin. Invest | 미소장 |
| 2 | Raisz LG, (1988) Hormonal regulation of bone growth and remodeling. In Cell and Molecular Biology of Vertebrate Hard Tissue CIBA Foundation Symposium 136, Wiley | 미소장 |
| 3 | Lee YS, (2001) Effect of isoflavones on proliferation and oxidative stress of MC3T3-E1 osteoblast-like cells, Korea soybean Digest | 미소장 |
| 4 | Jilka RL, (1998) Cytokines, bone remodeling and estrogen deficiency, Bone | 미소장 |
| 5 | Aldercreutz H, (1996) Phyto-estrogens in relation to cancer and other human health risks, Proc. Nutr. Soc | 미소장 |
| 6 | 금정철 ; 강경화 ; 김승보, (2001) MC3T3-EI 조골세포에서 에스트로겐이 종양괴사인자- α로 유도된 세포자연사 및 사이토카인 유전자 발현에 미치는 영향, Obstetrics & Gynecology Science | 미소장 |
| 7 | Orcel P, (2000) Secondary osteoporosis and glucocorticoid include osteoporosis, Ann. Med. Interne | 미소장 |
| 8 | Karen MP, (1995) Treatment of osteoporosis, Annu. Rev. Med | 미소장 |
| 9 | Stein GS, (1996) Montechino M. Transcriptional control of osteoblast growth and differentiation, Physiol. Rev | 미소장 |
| 10 | Ryan PJ, (1992) Osteoporosis and chronic back pain: A study with single-photon emission computed tomography bone scintigraphy, J. Bone Miner. Res | 미소장 |
| 11 | Cho SH, (1996) The effects of 17-β estradiol, medroxyprogesterone acetate and parathyroid hormone on the differentiation of osteoblast cell, Korean J. Obstet. Gynecol | 미소장 |
| 12 | Boonen A, (1997) The prevention of treatment of age-related osteoporosis in the elderly by systemic recombinant growth factor therapy (rhIGF-I or rhRGF-β): a perspective, J. Internal Med | 미소장 |
| 13 | Lee YS, (2001) Effect of isoflavones on proliferation and oxidatives stress of MC3T3-E1 osteoblastic like cells, Korea Soybean Digest | 미소장 |
| 14 | Choi EM, (2001) Soybean ethanol extract increases the funtion of osteoblastic MC3T3-E1 cells, Phytochemistry | 미소장 |
| 15 | Choi EM, (2002) Effects of soybean ethanol extract on the prostaglandin E2 and interleukin-6 production in osteoblastic cells, Food Res. Int | 미소장 |
| 16 | (2004) Herbal medicine, Young-lim Sa | 미소장 |
| 17 | Chena YC, (2001) Wogonin, baicalin, and baicalein inhibition of inducible nitric oxide synthase and cyclooxygenase-2 gene expressions induced by nitric oxide synthase inhibitors and lipopolysaccharide, Biochem. Pharmacol | 미소장 |
| 18 | Krakauer T, (2001) The flavonoid baicalin inhibits superantigen-induced inflammatory cytokines and chemokines, FEBS. Lett | 미소장 |
| 19 | Jerome AR, (1999) Melatonin Promotes Osteoblast Differentiation and Bone Formation, J. Biol. Chem | 미소장 |
| 20 | Green LM, (1984) Rapid colometric assay for cell viability: Application to the quantitation of cytotoxic and growth inhibitory lympokines, J. Immunol. Methods | 미소장 |
| 21 | Owen ME, (1985) Lineage of osteogenic cells and their relationship to the stromal system. in Bone and Mineral Research, edited by Peck, W.A, Elsevier Science Publisher | 미소장 |
| 22 | Martin JH, (1970) Mitochondrial granules in chondrocytes, osteoblasts and osteocytes. An ultrastructural and microincineration study, Clin. Orthop. Relat. R | 미소장 |
| 23 | Ernst M, (1989) Estradiol effects on proliferation messenger ribonucleic acid collagen and insulin-like growth factor- I and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones, Endocrinology | 미소장 |
| 24 | Sudo H, (1983) In vitro differentiation and calcification in new clonal osteogenic cell line derived from newborn mouse calvaria, J. Cell Biol | 미소장 |
| 25 | Kim KY, (1991) Primary culture of osteoblast, J. Korean Orthop. Assoc | 미소장 |
| 26 | Cho YH, (2001) Comparative estrogenic effects of Yak-Kong and Soy Bean on the proliferation of human osteoblastic cell line, MG-63, Korean J. Nutr. Soc | 미소장 |
| 27 | Stein GS, (1990) Relationship of cell growth to the regulation for tissue-specific gene expression during osteoblast differentiation, FASEB. J | 미소장 |
| 28 | Park SK, (2001) Effects of extract of natural products on alkaline phosphatase activity of MC3T3-E1 cells, Wonkwang Dental Medicine | 미소장 |
| 29 | Suda T, (1999) Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families, Endocr. Rev | 미소장 |
| 30 | Mundy GR, (1987) Osteoclast ontogeny and function. ;In: Bone and Mineral Research, Elsevier | 미소장 |
| 31 | Claudia MR, (2002) Down-Regulation of osteoclast differentiation by Daidzein via Caspase 3, J. Bone Miner. Res | 미소장 |
| 32 | Alice W, (2003) Potent inhibitory effect of naturally occurring flavonoids ruercetin and kaempferol on in vitro osteoclastic bone resorption, Biochem. Pharmacol | 미소장 |
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