대표어
한국학술지인용색인(NRF)
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초록보기
Background: We investigated whether the intubating condition change acoording to the methods of administration of propofol and rocuronium.
Methods: Ninety adult patients (ASA physical status I or II) undergoing elective surgery were randomly assigned to one of three groups; Group I (n = 30) received rocuronium (0.6 mg/kg) after administration of propofol (2 mg/kg), Group II (n = 30) received propofol and rocuronium simultaneously via different intravenous routes, and Group III (n = 30) received a mixture of propofol and rocuronium via same intravenous route. Intubation was attempted at 60 seconds after administration of rocuronium. Hemodynamic parameters (mean blood pressure, heart rate) were measured before and after propofol administration with 20 seconds interval. Intubating conditions (jaw relaxation, vocal cord movement, and response to tracheal intubation) were evaluated as excellent, good, fair and poor. Train of four counts were recorded at 60 seconds after administration of rocuronium.
Results: Excellent intubating conditions were obtained in 13% in group I, 60% in group II, 77% in group III. Mean train of four counts were 3.7 in group I, 3.4 in group II, and 3.5 in group III. Mean blood pressures were decreased gradually after propofol administration in all groups. However, heart rates were not changed in all groups.
Conclusions: At induction of anesthesia, simultaneous or mixed administration of propofol and rocuronium provides excellent or good intubating conditions 60 seconds after rocuronium administration. It could be an effective alternative to succinylcholine for rapid sequence induction of anesthesia.권호기사
참고문헌 (30건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | [Succinylcholine--update].  |
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| 2 | Mohamed N, Cynthia AL. Pharmacology of muscle relaxants and their antagonist. In: Miller’s anesthesia. 6th ed. Edited by Miller RD: Philadelphia, Elsevier. 2005, pp 489-91 | 미소장 |
| 3 | Mohamed N, Cynthia AL. Pharmacology of muscle relaxants and their antagonist. In: Miller’s anesthesia. 6th ed. Edited by Miller RD: Philadelphia, Elsevier. 2005, pp 504-5 | 미소장 |
| 4 | The Onset Time of Rocuronium Is Slowed by Esmolol and Accelerated by Ephedrine |
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| 5 | The dose effect of ephedrine on the onset time of vecuronium. |
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| 6 | The cardiorespiratory effects of ICI 35 868 in patients with valvular heart disease. |
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| 7 | The haemodynamic effects of intravenous induction |
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| 8 | Acute cardiovascular changes following disoprofol |
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| 9 | Hemodynamic effects of infusions of the emulsion formulation of propofol during nitrous oxide anesthesia in humans. |
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| 10 | The influence of age on propofol pharmacodynamics. |
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| 11 | Comparison of the effect-site k(eO)s of propofol for blood pressure and EEG bispectral index in elderly and younger patients. |
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| 12 | Spontaneous movements, local reactions and pain on injection of rocuronium |
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| 13 | Comparison of intubating conditions after administration of Org 9246 (rocuronium) and suxamethonium. |
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| 14 | Onset and duration of rocuronium and succinylcholine at the adductor pollicis and laryngeal adductor muscles in anesthetized humans. |
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| 15 | Onset of action of relaxants. |
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| 16 | Double-blind comparison of two doses of rocuronium and succinylcholine for rapid-sequence intubation |
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| 17 | Comparison of rocuronium, succinylcholine, and vecuronium for rapid-sequence induction of anesthesia in adult patients. |
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| 18 | Reexamined: The Recommended Endotracheal Intubating Dose for Nondepolarizing Neuromuscular Blockers of Rapid Onset |
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| 19 | A large simple randomized trial of rocuronium versus succinylcholine in rapid‐sequence induction of anaesthesia along with propofol |
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| 20 | Facilitation of rapid endotracheal intubations with divided doses of nondepolarizing neuromuscular blocking drugs. |
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| 21 | The priming principle. |
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| 22 | Priming with atracurium: improving intubating conditions with additional doses of thiopental. |
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| 23 | Refining the priming principle for vecuronium during rapid-sequence induction of anesthesia. |
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| 24 | Priming with nondepolarizing relaxants for rapid tracheal intubation: a double-blind evaluation. |
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| 25 | Precurarization with vecuronium and pancuronium in awake, healthy volunteers: the influence on neuromuscular transmission and pulmonary function. |
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| 26 | Jones RM. The priming principle: how does it work and should we be using it? Br J Anaesth 1989; 63: 1-3. | 미소장 |
| 27 | The effect of circulation time on the neuromuscular action of suxamethonium. |
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| 28 | The Effect of Ephedrine on the Onset Time of Rocuronium |
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| 29 | Rocuronium (ORG 9426) neuromuscular blockade at the adductor muscles of the larynx and adductor pollicis in humans. |
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| 30 | Neuromuscular effects of rocuronium on the diaphragm and adductor pollicis muscles in anesthetized patients. |
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