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Objective: We wanted to assess the long-term results of cyst ablation with using N-butyl cyanoacrylate (NBCA) and iodized oil in patients with autosomal dominant polycystic kidney disease (ADPKD) and symptomatic cysts.

Materials and Methods: Cyst ablation using a mixture of NBCA and iodized oil was performed in 99 cysts from 21 patients who had such symptoms as abdominal distension and pain. The collapse or reaccumulation of the ablated cysts after the procedure was assessed during the follow-up period of 36 to 90 months. The treatment effects, including symptom relief, and the clinical data such as the blood pressure and serum creatinine levels were also assessed, together with the complications.

Results: The procedure was technically successful in all 99 cysts from the 21 patients. Any procedure-related significant complications were not detected. Seventy-seven of 99 cysts (78%) were successfully collapsed on the follow-up CT. Twenty-two cysts showed reaccumulation during long-term follow-up period. The clinical symptoms were relieved in 17 of the 21 patients (76%). Four of 12 patients (33%) with hypertension and two of six patients (33%) with azotemia were improved. End stage renal disease (ESRD) occurred in six of the 21 patients (28%) during the follow-up period. The mean age of ESRD in our patients was 57 years. The mean time interval for the development of ESRD was 19 months.

Conclusion: Ablation using a mixture of NBCA and iodized oil may be an effective, safe method for obtaining symptom relief in patients with ADPKD.

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참고문헌 (29건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Autosomal Dominant Polycystic Kidney Disease 네이버 미소장
2 Autosomal dominant polycystic kidney disease. 네이버 미소장
3 Autosomal dominant polycystic kidney disease 네이버 미소장
4 Computed tomography of adult polycystic disease. 네이버 미소장
5 Inherited cystic diseases of the kidney. 네이버 미소장
6 THE NATURAL HISTORY OF SIMPLE RENAL CYSTS 네이버 미소장
7 Renal cystic disease. 네이버 미소장
8 Hartman DS. Renal cystic disease in multisystem conditions. Urol Radiol 1992;14:13-17 미소장
9 Renal and extrarenal manifestations of autosomal dominant polycystic kidney disease 네이버 미소장
10 Reduction of Cyst Volume for Symptomatic Management of Autosomal Dominant Polycystic Kidney Disease 네이버 미소장
11 Cyst decompression surgery for autosomal dominant polycystic kidney disease. 네이버 미소장
12 Recent advances in the clinical management of autosomal-dominant polycystic kidney disease. 네이버 미소장
13 Pain management in polycystic kidney disease 네이버 미소장
14 Pathophysiology and clinical management of polycystic kidney disease in women. 네이버 미소장
15 Cyst infection in polycystic kidney disease: a clinical challenge. 네이버 미소장
16 Chapman AB, Thickman D, Gabow PA. Percutaneous cyst puncture in the treatment of cyst infection in autosomal dominant polycystic kidney disease. Am J Kidney Dis 1996;16:252-255 미소장
17 Aspiration and sclerotherapy of symptomatic simple renal cysts: value of two injections of a sclerosing agent. 네이버 미소장
18 Treatment of simple renal cysts by percutaneous drainage with three repeated alcohol injections 네이버 미소장
19 Comparison of single and multiple sessions of percutaneous sclerotherapy for simple renal cyst 네이버 미소장
20 Seo TS, Oh JH, Yoon Y, Lim JW, Park SJ, Chang SG, et al. Acetic acid as a sclerosing agent for renal cysts: comparison with ethanol in follow-up results. Cardiovasc Intervent Radiol 2000;23:177-181 미소장
21 Cyst sclerotherapy with minocycline hydrochloride in patients with autosomal dominant polycystic kidney disease 네이버 미소장
22 Peyromaure M, Debre B, Flam TA. Sclerotherapy of a giant renal cyst with povidone-iodine. J Urol 2002;168:2525 미소장
23 Percutaneous Sclerotherapy of Renal Cysts with a Beta-Emitting Radionuclide, Holmium-166-chitosan Complex 소장
24 Renal cysts: treatment with alcohol. 네이버 미소장
25 Ethanol sclerotherapy for symptomatic simple renal cysts. 네이버 미소장
26 Percutaneous sclerotherapy of a giant benign renal cyst with alcohol 네이버 미소장
27 Ablation of Symptomatic Cysts Using Absolute Ethanol in 11 Patients with Autosomal-Dominant Polycystic Kidney Disease 소장
28 Change of spontaneous reaction of glue and lipiodol mixture during embolization after the addition of tungsten powder: in vitro study. 네이버 미소장
29 Renal cyst ablation with n-butyl cyanoacrylate and iodized oil in symptomatic patients with autosomal dominant polycystic kidney disease: preliminary report. 네이버 미소장