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Contents
The first case of antibiotic-associated colitis by Clostridium difficile PCR ribotype 027 in Korea / Chung Hyun Tae ; Sung-Ae Jung ; Hyun Joo Song ; Seong-Eun Kim ; Hee Jung Choi ; Miae Lee ; Yusun Hwang ; Heejung Kim ; Kyungwon Lee 1
[요약] 1
Introduction 1
Case report 1
Discussion 4
REFERENCES 4
초록보기
Clostridium difficile (C. difficile) is a common causative agent of pseudomembranous
colitis (PMC). C. difficile-associated diarrhea (CDAD) ranges from mild diarrhea to
life threatening PMC. Recently, a highly virulent strain of C. difficile polymerase chain
reaction ribotype 027 was found in North America, Europe, and Japan. A 52-yr-old
woman with anti-tuberculosis medication and neurogenic bladder due to traffic accident
experienced five episodes of C. difficile PMC after taking antibiotics for pneumonia
along with septic shock and acute renal failure. She was readmitted to the
intensive care unit and treated with oral vancomycin with refractory of oral metronidazole,
inotropics and probiotics for over 60 days. C. difficile isolated both at the
first and the last admission was identified as C. difficile ribotype 027 by ribotyping,
toxinotyping, and tcdC gene sequencing, which turned out the same pathogen as
the epidemic hypervirulent B1/NAP1 strain. This is the first case of C. difficile PCR
ribotype 027 in Korea. After discharge, she was maintained on probiotics and rifaximin
for 3 weeks. She had no relapse for 6 months.권호기사
참고문헌 (25건) : 자료제공( 네이버학술정보 )
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| 1 | Clostridium difficile–Associated Diarrhea  |
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| 2 | Treatment of Clostridium difficile-associated disease: old therapies and new strategies |
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| 3 | Narrative Review: The New Epidemic of Clostridium difficile-Associated Enteric Disease |
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| 5 | Clinical aspects of rifampicin-associated pseudomembranous colitis. |
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| 6 | First isolation of Clostridium difficile 027 in Japan. |
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| 7 | PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. |
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| 8 | A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates. |
미소장 |
| 9 | Comparative analysis of Clostridium difficile clinical isolates belonging to different genetic lineages and time periods. |
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| 10 | tcdC genotypes associated with severe TcdC truncation in an epidemic clone and other strains of Clostridium difficile. |
미소장 |
| 11 | Antibiotic-associated pseudomembranous colitis due to toxin-producing clostridia. |
미소장 |
| 12 | Antibiotic-Associated Diarrhea |
미소장 |
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미소장 |
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미소장 |
| 17 | Successful Treatment of Fulminant Clostridium difficile Infection with Fecal Bacteriotherapy |
미소장 |
| 18 | Mortality attributable to nosocomial Clostridium difficile-associated disease during an epidemic caused by a hypervirulent strain in Quebec. |
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| 19 | Treatment of Clostridium difficile Infection |
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| 21 | Detection of Toxigenic Clostridium difficile in Stool Specimens by the Polymerase Chain Reaction |
미소장 |
| 22 | Laboratory diagnosis of toxigenic Clostridium difficile by polymerase chain reaction: presence of toxin genes and their stable expression in toxigenic isolates from Japanese individuals. |
미소장 |
| 23 | Comparison of PCR-ribotyping, arbitrarily primed PCR, and pulsed-field gel electrophoresis for typing Clostridium difficile. |
미소장 |
| 24 | Measures to Control and Prevent Clostridium difficile Infection |
미소장 |
| 25 | Clinical Recognition and Diagnosis of Clostridium difficile Infection |
미소장 |
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