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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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Biofilms are microbial communities that form on a surface and are surrounded by extracellular polymeric substances. Candida biofilms are a cause of infections associated with medical devices. In the present study, an attempt was made to evaluate a significance of biofilm formation ability (BF) in virulence of C. albicans. C. albicans of 98 isolates, 24 commensal strains obtained from the oral cavities of healthy volunteers, 29 from blood culture, 25 from urine culture, and 20 from vaginal candidiasis, were assayed for BF, an ability to adhere to epithelial cells (ADH), cell surface hydrophobicity (CSH), and germ tube forming rate (GT). The relationships of BF with CSH, ADH, and GT were statistically examined. A positive correlation between BF and ADH was obtained, but the correlation (r=0.326) was relatively low. To assess BF as a factor contributing for candidiasis, mice lethality test was performed. The 10 isolates with the highest BF (mean survival rate, 24%) allow to kill mice more than those with the 10 lowest BF (mean survival rate, 47%). In addition, clinical strains isolated from blood culture, urine culture, and vaginal candidiasis showed higher BF than oral commensal strains. These results suggest BF may represent a virulent characteristic of C. albicans.

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Correlation between staphylococcal cassette chromosome mec type and coagulase serotype of methicillin-resistant Staphylococcus aureus Eui Kyung Cha ;Kyung Soo Chang ;Soo Myung Hwang pp.71-78

Molecular genetic characterization of shiga toxin-producing E. coli isolated from diarrhea patients and cattle in Gwangju area, Korea Min Ji Kim ;Sun Hee Kim ;Tae Sun Kim ;Hye-young Kee ;Jin-jong Seo ;Eun-Sun Kim ;Jong-Tae Park ;Jae K pp.79-95

Antimicrobial activity of methanol extract from Ficus carica leaves against oral bacteria Mi-Ran Jeong ;Hye-Young Kim ;Jeong-Dan Cha pp.97-102

The bacterial surface expression of SARS viral epitope using Salmonella typhi cytolysin A Hong Hua Piao ;Jihyoun Seong ;Man Ki Song ;Youn Uck Kim ;Dong-Jun Shin ;Hyon E Choy ;Yeongjin Hong pp.103-112

Protective effect of Ginsan against Vibrio vulnificus infection Hee Sam Na ;You-Jin Lim ;Yeon Sook Yun ;Yoon Hee Choi ;Jong Suk Oh ;Joon Haeng Rhee ;Hyun Chul Lee pp.113-118

Relationship between biofilm formation ability and virulence of Candida albicans Su Jung Park ;Sun Ju Choi ;Woon-Seob Shin ;Hyuk Min Lee ;Kkot Sil Lee ;Kyoung-Ho Lee pp.119-124

Genetic characteristics and phylogenetic analysis of influenza type B viruses isolated from Nasopharyngeal suction samples of Korean patients Yun Hee Baek ;Young Jun Song ;Min-Suk Song ;Philippe Noriel Q. Pascua ;Jun Han Lee ;Heon-Seok Han ;S pp.125-136

Construction of the porcine endogenous retrovirus envelope Glycoprotein A and B specific antibody Jung Eun Lee ;Gye-Woong Kim ;Young Bong Kim ;Hong Yang Park pp.137-143

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