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Background and Objectives: Left ventricular hypertrophy (LVH) is a major cardiovascular complication and an
important predictor of mortality in patients with end stage renal disease. Some studies have shown that the serum
aldosterone levels are correlated with LVH in non-diabetic patients undergoing hemodialysis. The objective of this
study was to elucidate the relationships between serum biomarkers, including aldosterone, and echocardiographic
findings, such as LVH, in patients on peritoneal dialysis. Subjects and Methods: Thirty patients on continuous
ambulatory peritoneal dialysis (CAPD) for >12 months at Soonchunhyang University Cheonan Hospital were
included. Transthoracic echocardiography was performed and the left ventricular mass index (LVMI) was calculated
using the Devereux formula. Serum biomarkers {N-terminal pro B-type natriuretic peptide (NT-proBNP),
troponin T, C-reactive protein, renin, and aldosterone} were measured. Results: Sixteen of 30 patients had LVH
on the basis of the LVMI. The mean serum aldosterone level was 62.53?0.73 pg/mL (range, 5.03-250.68 pg/mL).
LVH, on the basis of the LVMI, was not correlated with the serum aldosterone level. The serum aldosterone levels
were not associated with echocardiographic findings, even with co-existing diabetes mellitus. The LVMI had a negative
correlation with the hemoglobin (r=-0.405, p=0.029) and hematocrit (r=-0.374, p=0.042), and a positive
correlation with NT-proBNP (r=0.560, p=0.002). The other biomarkers (renin, aldosterone, troponin T, and Creactive
protein) were not correlated with the LVMI. The LVMI was correlated with the left atrium volume index
(r=0.675, p<0.001). Conclusion: NT-proBNP is a good marker to predict LVH in patients undergoing CAPD. The
serum aldosterone level is not correlated with LVMI, even with co-existing diabetes mellitus.| 번호 | 참고문헌 | 국회도서관 소장유무 |
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| 1 | Clinical and echocardiographic disease in patients starting end-stage renal disease therapy. ![]() |
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| 2 | Impact of left ventricular hypertrophy on survival in end-stage renal disease. ![]() |
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| 3 | Inflammation, residual kidney function, and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and cardiovascular death risk of peritoneal dialysis patients. ![]() |
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| 4 | Impaired renal clearance explains elevated troponin T fragments in hemodialysis patients. ![]() |
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| 5 | Prognostic value of troponin T in hemodialysis patients is independent of comorbidity. ![]() |
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| 6 | Cardiac troponin T and C-reactive protein for predicting prognosis, coronary atherosclerosis, and cardiomyopathy in patients undergoing long-term hemodialysis. ![]() |
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| 7 | Diagnostic value of troponin T for alterations in left ventricular mass and function in dialysis patients. ![]() |
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| 8 | N-terminal pro-brain natriuretic peptide: an independent risk predictor of cardiovascular congestion, mortality, and adverse cardiovascular outcomes in chronic peritoneal dialysis patients. ![]() |
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| 9 | Changes in left ventricular anatomy and function in hypertension and primary aldosteronism. ![]() |
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| 10 | Left ventricular mass and geometry before and after etiologic treatment in renovascular hypertension, aldosterone-producing adenoma, and pheochromocytoma. ![]() |
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| 11 | Role of aldosterone in left ventricular hypertrophy among African-American patients with end-stage renal disease on hemodialysis. ![]() |
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| 12 | Involvement of aldosterone in left ventricular hypertrophy of patients with end-stage renal failure treated with hemodialysis ![]() |
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| 13 | Left ventricular mass as a predictor of development of hypertension. ![]() |
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| 14 | The spectrum of left ventricular hypertrophy in a general population sample: the Framingham Study. ![]() |
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| 15 | Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. ![]() |
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| 16 | Recommendations for chamber quantification ![]() |
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| 17 | Functional Relevance of Aldosterone for the Determination of Left Ventricular Mass ![]() |
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| 18 | Studies on Plasma Renin and Aldosterone in Essential Hypertension ![]() |
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| 19 | Catecholamines, renin, aldosterone and arterial pressure in patients on chronic hemodialysis treatment. ![]() |
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| 20 | Associations between Sympathetic Activity, Plasma Concentrations of Renin, Aldosterone, and Parathyroid Hormone, and the Degree of Intractability of Blood Pressure Control in Hemodialysis Patients | 소장 |
| 21 | Relationships between left ventricular mass and the renin-angiotensin system, catecholamines, insulin and leptin. ![]() |
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| 22 | Plasma Renin Activity and Clinical Implication in Korean Hypertensive Patients | 소장 |
| 23 | Relation of arterial structure and function to left ventricular geometric patterns in hypertensive adults ![]() |
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| 24 | Cardiac and arterial interactions in end-stage renal disease. ![]() |
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| 25 | Adverse prognostic significance of concentric remodeling of the left ventricle in hypertensive patients with normal left ventricular mass ![]() |
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| 26 | Preload dependence of doppler-derived indexes of left ventricular diastolic function in humans ![]() |
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| 27 | Left atrial volume as a morphophysiologic expression of left ventricular diastolic dysfunction and relation to cardiovascular risk burden ![]() |
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| 28 | The Influence of the Left Ventricular Geometry on the Left Atrial Size and Left Ventricular Filling Pressure in Hypertensive Patients, as Assessed by Echocardiography | 소장 |
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