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Infections after living donor liver transplantation in children / Jeong Eun Kim ; Seak Hee Oh ; Kyung Mo Kim ; Bo Hwa Choi ; Dae Yeon Kim ; Hyung Rae Cho ; Yeoun Joo Lee ; Kang Won Rhee ; Seong Jong Park ; Young Joo Lee ; Sung Gyu Lee 1
[요약] 1
Introduction 1
Materials and methods 1
Patients 1
Perioperative management 2
Immunsuppression 2
Diagnosis of infection 2
Results 2
Overall incidence of infections 2
Bacterial infections 3
Fungal and parasitic infections 3
Viral infections 3
Cause of death after LDLT 4
Discussion 4
Acknowledgement 4
References 4
The aim of this study was to evaluate the infectious complications after living donor
liver transplantation (LDLT) in children. We enrolled 95 children (38 boys and 57
girls) who underwent LDLT from 1994 to 2004. The median age was 22 months
(range, 6 months to 15 yr). We retrospectively investigated the proven episodes of
bacterial, viral, and fungal infection. There occurred 150 infections in 67 (70%) of
95 patients (1.49 infections/patient); 74 in 43 patients were bacterial, 2 in 2 were
fungal, and 74 in 42 were viral. The most common sites of bacterial infection were
the bloodstream (33%) and abdomen (25%). Most of the bacterial infections occurred
within the first month after LDLT. Bacterial and fungal infections did not result in any
deaths. The most common causes of viral infection were Epstein-Barr virus in 37
patients and cytomegalovirus in 18. Seven of the 14 deaths after LDLT were associated
with viral infection. Our study suggests that infection is one of the important
causes of morbidity and mortality after LDLT. Especially careful monitoring and management
of viral infections is crucial for improving the outcome of LDLT in children.*표시는 필수 입력사항입니다.
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도서위치안내: 정기간행물실(524호) / 서가번호: 국내17
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