본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

초록보기

Culture broth of an actinomycete isolate, Nocardia sp. CS682 showed specifically higher antibacterial activity against methicilin resistant Staphylococcus aureus (MRSA). Purified substance from the organism, CS-682, which is active against MRSA and Micrococcus leuteus, is a C28H37NO8 (M+H+, observed: 516.83) and identified as an unusual macrolide antibiotic, nargenicin. The chemical structure of CS-682 was identified by FT-IR, 1H-NMR, 13C-NMR, and (툵-툵 and 툵-13H) COSY. The anti-MRSA activity of CS-682 was stronger than that of oxacillin, vancomycin, monensin, erythromycin, and spiramycin. Phylogenetic analysis showed that strain CS682 is closely related to Nocardia tenerifensis DSM 44704T (98.7% sequence similarity), followed by N. brasiliensis ATCC 19296T (98.4% sequence similarity). The ability of Nocardia sp. CS682 to produce nargenicin was unique.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
(A)New stilbene glucoside gallate from the roots of Polygonum multiflorum Hyun Ki Kim ;Yeon Hee Choi ;Jae Seok Choi ;Sang Un Choi ;Young Sup Kim ;Kang Ro Lee ;Young-Kyoon Kim pp.1225-1229

(The)Synthesis and preliminary activity assay in vitro of peptide-like derivatives as APN inhibitors Shao-hua Li ;Gang Li ;Hui-ming Huang ;Fang Xiong ;Cheng-mei Liu ;Guo-gang Tu pp.1231-1239

Microbial metabolites of 8-prenylnaringenin, an estrogenic prenylflavanone Hyun Jung Kim ;So-Hyun Kim ;Bok Yun Kang ;Ik-Soo Lee pp.1241-1246

Rapid analysis of proteomic biomarkers expressed in human endometrial stromal cells during decidualization Kyoung-Jin Oh ;Hye-Jin Choi ;Mee-Sup Yoon ;Jung-Hye Hwang ;Sung Yeoul Chang ;Yong-Seok Kim ;Joong-So pp.1247-1255

(The)Mechanism of the late preconditioning effect of 3-nitropropionic acid Bilgen Basgut ;Eda Aypar ;Ertug Basgut ;K. Okhan Akın ;Nedret Kılıc ;Iclal Cakıcı pp.1257-1263

(The)Retention behavior of ginsenosides in HPLC and its application to quality assessment of radix ginseng Ping Hu ;Guo-An Luo ;Qing Wang ;Zhong-Zhen Zhao ;Wan Wang ;Zhi-Hong Jiang pp.1265-1273

Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol Hyun-Joo Jung ;Yun Seon Song ;Chang-Jin Lim ;Eun-Hee Park pp.1275-1279

Antiproliferative effects of quercetin through cell cycle arrest and apoptosis in human breast cancer MDA-MB-453 cells Eun Jeong Choi ;Su Mi Bae ;Woong Shick Ahn pp.1281-1285

Cytotoxic activities of diarylheptanoids from Alnus japonica Sun Eun Choi ;Kwang Ho Kim ;Joo Hee Kwon ;Seung Bum Kim ;Ha Won Kim ;Min Won Lee pp.1287-1289

APE1/Ref-1 promotes the effect of angiotensin Ⅱ on Ca^2+^-activated K^+^ channel in human endothelial cells via suppression of NADPH oxidase Won Sun Park ;Eun A Ko ;In Duk Jung ;Youn Kyoung Son ;Hyoung Kyu Kim ;Nari Kim ;So Youn Park ;Ki Wha pp.1291-1301

Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells Hyo-Hyun Park ;Soyoung Lee ;Hee-Young Son ;Seung-Bin Park ;Mi-Sun Kim ;Eun-Ju Choi ;Thoudam S.K. Sin pp.1303-1311

Norlignan derivatives from Curculigo crassifolia and their DPPH radical scavenging activity Kai-Jin Wang ;Ning Li pp.1313-1316

Identification of glutathione conjugates of 1-bromopentane and its hepatotoxicity in female BALB/c mice Sang Kyu Lee ;Dong Ju Lee ;Hye Hyun Yoo ;Ju Hyun Kim ;Young Min Seo ;Sil Shin ;Jae Ho Choi ;Tae Won pp.1317-1323

(A)New ferulic acid ester and other constituents from Dracocephalum peregrinum Li-Min Dai ;Chun-Chao Zhao ;Hui-zi Jin ;Jian Tang ;Yun-Heng Shen ;Hui-Liang Li ;Cai-Yun Peng ;Wei-Do pp.1325-1329

Regulation of lysophosphatidic acid-induced COX-2 expression by ERK1/2 activation in cultured feline esophageal epithelial cells Do Young Kim ;Hyun Ju Song ;Ji Hoon Jeong ;Jung Sook Suh ;Uy Dong Sohn pp.1331-1338

Production, isolation and biological activity of nargenicin from Nocardia sp. CS682 Jae Kyung Sohng ;Tokutaro Yamaguchi ;Chi Nam Seong ;Keun Sik Baik ;Seong Chan Park ;Hyo Jeong Lee ;S pp.1339-1345

Pharmacokinetics of guanosine in rats following intravenous or intramuscular administration of a 1:1 mixture of guanosine and acriflavine, a potential antitumor agent Dae Hwan Shin ;Kyu Seok Choi ;Byung Suk Cho ;Sukgil Song ;Dong-Cheul Moon ;Jin Tae Hong ;Chong-Kil L pp.1347-1353

Extensive intracellular accumulation of ID-6105, a novel anthracycline, in SK-OV-3 ovarian cancer cells Dae Hwan Shin ;Kyu Seok Choi ;Sang-Ae Park ;Byung Suk Cho ;Hong-Sub Lee ;Jung-Su Ryu ;Tae-Yong Kim ; pp.1355-1361

Physicochemical studies of a newly synthesized molecule, 6-methyl-3-phenethyl-3,4-dihydro-1H-quinazoline-2-thione (JSH18) for topical formulations Sujin Kim ;Sang-Hun Jung ;Cheong-Weon Cho pp.1363-1368

In vitro and in vivo evaluation of ranitidine hydrochloride loaded hollow microspheres in rabbits Yu-meng Wei ;Ling Zhao pp.1369-1377

참고문헌 (29건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Celmer, W. D., (1980) Structure of natural antibiotic CP-47,444, J. Am. Chem. Soc 미소장
2 Chadwick, P. R., (1996) Glycopeptide-resistant enterococci isolated from uncooked meat, J. Antimicrob. Chemother 미소장
3 Chun, J., (1995) A phylogenetic analysis of the genus Nocardia with 16S rRNA gene sequences, Int. J. Syst. Bacteriol 미소장
4 Chun, J., (2000) Nocardiopsis kunsanensis sp. nov., a moderately halophilic actinomycete isolated from a saltern, Int. J. Syst. Evol. Microbiol 미소장
5 Clinical and Laboratory Standards Institute (CLSI), (2003) Performance Standards for Antimicrobial Disk Susceptibility Tests - Eighth Edition. Approved Standard (M2-A8), Wayne, PA, 미소장
6 Coque, T. M., (1996) Vancomycin-resistant enterococci from nosocomial, community, and animal sources in the United States, Antimicrob. Agents Chemother 미소장
7 Felsenstein, J., (1981) Evolutionary trees from DNA sequences: a maximum likelihood approach, J. Mol. Evol 미소장
8 Franciolli, M., (1991) Beta-lactam resistance mechanism of methicillin-resistance Staphylococus aureus, J. Infect. Dis 미소장
9 Gordon, R. E., (1974) Nocardia coeliaca, Nocardia autotrophica, and the Nocardin strain, Int. J. Syst. Bacteriol 미소장
10 Hasegawa, T., (1983) A rapid analysis for chemical grouping of aerobic actinomycetes, J. Gen. Appl. Microbiol 미소장
11 Hayakawa, M., (1996) Combined use of trimethoprim with nalidixic acid for the selective isolation and enumeration of actinomycetes from soil, Actinomycetol 미소장
12 Isik, K., (1999) Nocardia salmonicida nom. rev., a fish pathogen, Int. J. Syst. Bacteriol 미소장
13 Jukes, T. H., (1969) Evolution of protein molecules, Mammalian Protein Metabolism, Academic Press 미소장
14 Kämpfer, P., (2004) Nocardia tenerifensis sp. nov, Int. J. Syst. Evol. Microbiol 미소장
15 Kim, D., (1996) Analysis of thermophilic clades within the genus Streptomyces by 16S ribosomal DNA sequence comparisons, Int. J. Syst. Bacteriol 미소장
16 Kim, S. A., (2004) Molecular genotyping and antibiotic susceptibility of methicillin-resistant Staphylococcus aureus isolated from patients specimen, 미소장
17 Kim, S. H., (1995) Four cases of vancomycin-resistant enterococci infection, Kor. J. Clin. Pathol 미소장
18 MIDI, Inc., (1999) Sherlock Microbial Identification System Operating Manual, MIDI, Inc. 미소장
19 Murray, B. E., (1995) What can we do about vancomycin-resistant enterococci?, Clin. Infect. Dis 미소장
20 Noble, W. C., (1992) Co-transfer of vancomycin and other resistance genes from Enerococcus faecalis NCTC 12201 to Staphylococcus aureus, FEMS Microbiol. Lett 미소장
21 Pieters, R., (1988) Adaptation of the rapid automated tetrazolium dye based (MTT) assay for chemosensitivity testing in childhood leukemia, Cancer Lett 미소장
22 Saitou, N., (1987) The neighbor-joining method: a new method for reconstructing phylogenetic trees, Mol. Biol. Evol 미소장
23 성치남, (2004) Prevalence and characterization of vancomycin-resistant enterococci in chicken intestines and humans of Korea, Archives of Pharmacol Research 미소장
24 Shirling, E. B., (1966) Methods for characterization of Streptomyces species, Int. J. Syst. Bacteriol 미소장
25 Swofford, D. L., (1998) Phylogenetic analysis using parsimony (PAUP), Sinauer Associates 미소장
26 Van Horn, K. G., (1996) Selective isolation of vancomycin-resistant enterococci, J. Clin. Microbiol 미소장
27 Wampler, J. L., (1998) Effects of laidlomycin propionate and monensin on glucose utilization and nutrient transport by Streptococcus bovis and Selenomonas ruminantium, J. Anim. Sci 미소장
28 Yamamura, H., (2005) Nocardia takedensis sp. nov., isolated from moat sediment and scumming activated sludge, Int. J. Syst. Evol. Microbiol 미소장
29 Jin-cheolYoo ; 한지만 ; Seung-KwanNam ; Keun-shikBaik ; Jung-sunJo ; Chi-namSeong, (2002) Characterization of a Streptomycete Isolate Producing the Potent Cytotoxic Substance, Nonadecanoic Acid, The Journal of Microbiology 미소장

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기