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Background: Psychological factors are increasingly recognized for their influence on the course of asthma, on a worldwide basis. The aim of this study was to assess the presence of depression, anxiety, and asthma-related quality of life in patients with asthma and to evaluate their impact on severity and control of asthma.

Methods: We assessed the severity of asthma by comparing patients’ current medications to GINA guideline. The patients were classified into the controlled group (asthma patients with controlled disease) or into the uncontrolled group (asthma patients with uncontrolled disease), which included partly controlled and uncontrolled patients, again based on GINA guideline 2004. Patient-reported depressive symptoms, anxiety, and asthma-related quality of life were evaluated using the Beck Depression Inventory (BDI), the State-Trait Anxiety Inventory (STAI), and Korean asthma quality of life (KAQLQ).

Results: One hundred and twenty patients were enrolled (mean age, 55±1 years; 65% women). Among the 120 patients, 14 (12%) patients were classified as having mild asthma, 88 (73%) as having moderate asthma, and 18 (15%) as having severe asthma. Eighty-one (67%) of the 120 patients were controlled. The asthma-related quality of life showed the difference according to severity of asthma (p=0.002). The prevalence of depression was lower (10% vs 26%, p=0.024) and the asthma-related quality of life was higher (59.951 (29∼75) vs 35.103 (18∼72), p≤0.001) in the controlled group. Higher trait anxiety score and lower asthma-related quality of life were associated with depression (p＜0.001, p=0.002, respectively).

Conclusion: Psychological factors, such as anxiety and depression, are strongly associated with asthma control. Therefore, screening and management of depression is needed in patients with asthma.

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참고문헌 (26건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Cho SH, Park HW, Rosenberg DM The current status of asthma in Korea. J Korean Med Sci 2006;21:181-7. 미소장
2 Global Initiative for Asthma (GINA). 2006 revision:global strategy for asthma management and prevention [Internet]. GINA; 2006 [cited 2010 Oct 14]. Available from: http://ginasthma.org. 미소장
3 Characteristics of the Elderly Asthma 소장
4 Depression and Anxiety in Outpatients with Chronic Obstructive Pulmonary Disease 소장
5 Asthma and Serious Psychological Distress 네이버 미소장
6 Strine TW, Mokdad AH, Balluz LS, Berry JT, Gonzalez O. Impact of depression and anxiety on quality of life,health behaviors, and asthma control among adults in the United States with asthma, 2006. J Asthma 2008;45:123-33. 미소장
7 Hahn HM, Yum TH, Shin YW, Kim KH, Yoon DJ,Chung KJ. A standardization study of Beck depression inventory in Korea. J Korean Neuropsychiatr Assoc 1986;25:487-502. 미소장
8 Spielberger CD, Gorsuch RL, Lushene RE. Manual for the State-Trait Anxiety Inventory (Form X). Palo Alto:Consulting Psychologists Press; 1970. 미소장
9 Multi-center study for the utilization of quality of life questionnaire for adult Korean asthmatics (QLQAKA) 소장
10 Clinical predictors of health-related quality of life depend on asthma severity. 네이버 미소장
11 Association of asthma control with health care utilization and quality of life. 네이버 미소장
12 Correlation between the Korean Version of Asthma Control Test and Health-Related Quality of Life in Adult Asthmatics 소장
13 Nonalcoholic fatty liver disease. 네이버 미소장
14 Korea Pharmaceutical Manufacturers Association. Drug market statistics in 2004 [Internet]. Seoul: Korea Pharmaceutical Manufactures Association; c2009 [cited 2005 Jan 23]. Available from: http://www.kpma.or.kr 미소장
15 Prevalence of Depression and Anxiety in Outpatients with Chronic Airway Lung Disease 소장
16 Depression and anxiety in elderly outpatients with chronic obstructive pulmonary disease: prevalence, and validation of the BASDEC screening questionnaire 네이버 미소장
17 Asthma symptoms associated with depression and lower quality of life: a population survey. 네이버 미소장
18 Asthma and depression: a pragmatic review of the literature and recommendations for future research. 네이버 미소장
19 The Asthma/Mental Health Nexus in a Population-Based Sample of the United States 네이버 미소장
20 Psychobiological aspects of asthma and the consequent research implications. 네이버 미소장
21 Clinical predictors of health-related quality of life depend on asthma severity. 네이버 미소장
22 The impact of uncontrolled asthma on absenteeism and health-related quality of life. 네이버 미소장
23 Mancuso CA, Peterson MG, Charlson ME. Effects of depressive symptoms on health-related quality of life in asthma patients. J Gen Intern Med 2000;15:301-10. 미소장
24 The association of comorbid anxiety and depression with asthma‐related quality of life and symptom perception in adults 네이버 미소장
25 Kim JT, Shin DK. A Study based on the standardization of the STAI for Korea. New Med J 1978;21:69-75. 미소장
26 Patient-Reported and Physician-Reported Depressive Conditions in Relation to Asthma Severity and Control 네이버 미소장

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