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Root extract of Lythrum salicaria reported a hepato-protective effect on CCl4-induced liver toxicity of rat was

prepared into fractions such as n-hexane up layer (HA), n-hexane down layer (HB), diethyl ether (E), ethylacetate (EA), nbutanol

(B) and water (W). Fractions prepared were tested their activities in vitro and in vivo condition. All of the fractions

showed effective antioxidant asctivities on DPPH radical and CuSO4-induced oxidation of human low density lipoprotein

and E fraction showed the highest inhibitory effect (98.1% at 50 ㎍/㎖) on linoleic acid autoxidation at 40℃, which was

more effective than α-tocopherol (82.4%). Five fractions (H = HA plus HB, E, EA, B, and W, 150 ㎎/㎏/day) were fed into

Sprague Dawley, male rats for 4 days, which were intoxicated with intra-peritoneal injection of carbon tetrachloride

(1 ㎖/㎏ in corn oil) at the 4th day and were sacrificed in 24 hrs. Serum tumor necrosis factor-alpha (TNF-α), a proinflammatory

cytokine, elevated with CCl4-intoxication in negative control group (83 pg/㎖) was significantly decreased in E fraction-

supplemented group (18 pg/㎖). Cu, Zn-superoxide dismutase (SOD) activity increased in negative control group

(0.12 U/㎎ protein) was decreased in E fraction (0.07 U/㎎ protein). From the results, it is suggested that ether fraction from

root extract of L. salicaria would be a potent antioxidant candidate for ameliorating liver injury induced by chemical intoxicant.

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맥문동 유수추출물이 NGF의 mRNA발현과 단백질 분비에 미치는 영향 최선일 ;박지희 ;허윤경 ;이연경 ;김지은 ;남소희 ;구준서 ;장민주 ;이희섭 ; pp.291-297

털부처꽃의 채취부위 및 채취시기에 따른 일반성분 함량 및 생리활성 이승은 ;박춘근 ;김선림 ;서진숙 ;김금숙 ;이정훈 ;박충범 ;김영철 pp.298-304

Inhibitory effect of quercetin-3-0-α-L-rhamnopyranoside from Chamaecyparis obtuse on aldose reductase and sorbitol accumulation Seon Ha Kim ;Jin Kyu Kim ;Yeon Sil Lee ;Young Soo Bae ;Soon Sung Lim pp.305-310

Determination of luteolin in the different parts of lithospermum erythrorhizon by HPLC Saem Han ;Jun Yeon Park ;Sul Lim Lee ;So Youn Mok ;Hye Min Kim ;Jeong Min Lee ;Young Hee Ahn ;Sang H pp.311-314

측백나무 열매 추출물의 항균활성 염태현 ;임흥빈 pp.315-322

털부처꽃 뿌리로부터 조제된 분획물의 생리활성 이승은 ;김금숙 ;한희선 ;이은숙 ;김영옥 ;이정훈 ;성낙술 ;이상원 ;김영철 pp.323-328

Multiplex PCR을 이용한 독활 류 식물로부터 Aralia continentalis 감별 이권진 ;도의정 ;고병섭 ;이미영 ;오승은 pp.329-337

한약재 중 아플라톡신 Monitoring 이성득 ;김연선 ;윤용태 ;박애숙 ;신영 ;김화순 ;김유경 ;최병현 pp.338-344

2009년 서울지역 유통 한약재의 이산화황 잔류실태 분석 윤용태 ;이성득 ;박애숙 ;신영 ;김화순 ;김유경 ;최병현 pp.345-360

참고문헌 (29건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Antilisterial Activity of Some Plants Used in Folk Medicine 네이버 미소장
2 Bioactivity guided isolation of antimicrobial compounds from Lythrum salicaria 네이버 미소장
3 Antioxidant Determinations by the Use of a Stable Free Radical 네이버 미소장
4 Antioxidant and antimicrobial activity of seed from plants of the Mississippi river basin 네이버 미소장
5 Prevention of hepatic cirrhosis in rats by hydroxyl radical scavengers 네이버 미소장
6 Csonka C, Pataki T, Kovacs P, Muller SL, Schroeter ML, Tosaki A and Blasig IE. (2000). Effects of oxidative stress on the expression of antioxidative defense enzymes in spontaneously hypertensive rat hearts. Free Radical Biological Medicine. 29:612-619. 미소장
7 Superoxide dismutase assays. 네이버 미소장
8 Oxidative stress as a major culprit in kidney disease in diabetes. 네이버 미소장
9 Frei B. (1994). Natural antioxidants in human health and disease. Academic Press, Boston, Messachusets, USA. p. 25-55. 미소장
10 Habig WH, Pabst MJ and Jakoby WB. (1974). Glutathione-Stransferase: the first enzymatic step in mercapturic acid formation. Journal of Biological. Chemistry. 249:7130-7139. 미소장
11 Humadi SS and Istudor V. (2009). Lythrum salicaria (purple loosetrife) medicinal use, extraction and identification of its total phenolic compounds. Farmacia. 57:192-200. 미소장
12 Jeong HG, You HJ, Park SJ, Moon AR, Chung YC, Kang SK and Chun HK. (2002). Hepatoprotective effects of 18β- glycyrrhetinic acid on carbon tetrachloride-induced liver injury: inhibition of cytochrome P4502E1 expression. Pharmacological Research. 46:221-227. 미소장
13 Jung BS and Shin MG. (1990). Hyangyak-Seangyak Great Encyclopedia. Young-Lim Publishing Co., Seoul. p. 730-731. 미소장
14 Effects of Lythrum salicaria in normoglycemic rats 네이버 미소장
15 Effects of Lythrum salicaria extracts on hyperglycemic rats and mice 네이버 미소장
16 Antioxidant Activity of Ulmus davidiana var. japonica N. and Hemipteleae davidii P. 소장
17 털부처꽃의 항산화 및 간장보호활성 네이버 미소장
18 Antioxidant and anti-fibrotic properties of root extract of Lythrumsalicaria L. in CCL₄-induced liver fibrosis rat model 네이버 미소장
19 Lee WC. (1996). Lineamenta florae Korea. Academy Publishing Company, Seoul. p. 748. 미소장
20 Liber CS and DeCarli LM. (1970). Hepatic microsomal ethanoloxidizing system. Journal of Biological Chemistry. 245:2505- 2512. 미소장
21 In vitro antioxidant effects of estrogens with a hindered 3-OH function on the copper-induced oxidation of low density lipoprotein 네이버 미소장
22 Effects of Ginsenoside Rb2 on the Antioxidants in SAM - R / 1 Mice 네이버 미소장
23 Rauha JP, Remes S, Heinonen M, Hopia A, Kahkonene M, Kujala T, Pihlaja K, Vuorela H and Vuorela P. (2000). Antimicrobial effects of finnish plant extracts containing flavonoids and other phenolic compounds. International Journal of Food Microbiology. 56:3-12. 미소장
24 Lipid peroxidation in human proteinuric disease 네이버 미소장
25 A Simple Screening Method for Antioxidants and Isolation of Several Antioxidants Produced by Marine Bacteria from Fish and Shellfish. 네이버 미소장
26 Antioxidant, anti-inflammatory, anti-nociceptive activities and composition of Lythrum salicaria L. extracts 네이버 미소장
27 Plant Flavonoids, Especially Tea Flavonols, Are Powerful Antioxidants Using an in Vitro Oxidation Model for Heart Disease 네이버 미소장
28 Protective effects of dehydrocavidine on carbon tetrachloride-induced acute hepatotoxicity in rats 네이버 미소장
29 Yoshida T, Mori K, Hatano T, Okumura T, Uehara I, Komagoe K, Fujita Y and Okuda T. (1989). Studies on inhibition mechanism of autoxidation by tannin and flavonoids. v. radical-scavenging effects of tannins and related polyphenols on 1,1-diphenyl-2-picrylhydrazyl radical. Chemical Pharmaceutical Bulletin. 37:1919-1921. 미소장

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