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Contents

Effectiveness of drug-eluting stents versus bare-metal stents in large coronary arteries in patients with acute myocardial infarction / Doo Sun Sim ; Myung Ho Jeong ; Youngkeun Ahn ; Young Jo Kim ; Shung Chull Chae ; Taek Jong Hong ; In Whan Seong ; Jei Keon Chae ; Chong Jin Kim ; Myeong Chan Cho ; Ki Bae Seung ; Seung Jung Park 1

[요약] 1

Introduction 1

Materials and methods 2

Patient population 2

PCI procedure and medications 2

Study definitions and endpoints 2

Statistical analysis 2

Ethics statement 3

Results 3

Discussion 4

Acknowledgments 5

References 5

Author summary 7

초록보기

This study compared clinical outcomes of drug-eluting stents (DES) versus bare-metal stents (BMS) in large coronary arteries in patients with acute myocardial infarction (MI). A total of 985 patients who underwent single-vessel percutaneous coronary intervention (PCI) in large coronary arteries (≥ 3.5 mm) in lesions < 25 mm were divided into DES group (n = 841) and BMS group (n = 144). Clinical outcomes during 12 months were compared. In-hospital outcome was similar between the groups. At six months, death/MI rate was not different. However, DES group had significantly lower rates of target-lesion revascularization (TLR) (1.7% vs 5.6%, P= 0.021), target-vessel revascularization (TVR) (2.2% vs 5.6%, P= 0.032), and total major adverse cardiac events (MACE) (3.4% vs 11.9%, P= 0.025). At 12 months, the rates of TLR and TVR remained lower in the DES group (2.5% vs 5.9%, P= 0.032 and 5.9% vs 3.1%, P= 0.041), but the rates of death/MI and total MACE were not statistically different. The use of DES in large vessels in the setting of acute MI is associated with lower need for repeat revascularization compared to BMS without compromising the overall safety over the course of one-year follow-up.

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참고문헌 (30건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Predictive Factors of Restenosis After Coronary Stent Placement 네이버 미소장
2 Vessel size and long-term outcome after coronary stent placement. 네이버 미소장
3 Is bare-metal stenting superior to balloon angioplasty for small vessel coronary artery disease? Evidence from a meta-analysis of randomized trials 네이버 미소장
4 Angiographic Findings of the Multicenter Randomized Study With the Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent (RAVEL) 네이버 미소장
5 Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. 네이버 미소장
6 A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. 네이버 미소장
7 Clinical efficacy of polymer-based paclitaxel-eluting stents in the treatment of complex, long coronary artery lesions from a multicenter, randomized trial: support for the use of drug-eluting stents in contemporary clinical practice. 네이버 미소장
8 Comparison of a polymer-based paclitaxel-eluting stent with a bare metal stent in patients with complex coronary artery disease: a randomized controlled trial. 네이버 미소장
9 Malaria 네이버 미소장
10 Differences in Clinical Outcomes Between Patients With ST-Elevation Versus Non-ST-Elevation Acute Myocardial Infarction in Korea. 소장
11 Current management of acute myocardial infarction: experience from the Korea Acute Myocardial Infarction Registry. 네이버 미소장
12 Outcomes with the paclitaxel-eluting stent in patients with acute coronary syndromes: analysis from the TAXUS-IV trial. 네이버 미소장
13 Sirolimus-eluting versus uncoated stents in acute myocardial infarction. 네이버 미소장
14 Valgimigli M, Percoco G, Malagutti P, Campo G, Ferrari F, Barbieri D, Cicchitelli G, McFadden EP, Merlini F, Ansani L, Guardigli G, Bettini A, Parrinello G, Boersma E, Ferrari R; STRATEGY Investigators. Tirofiban and sirolimus-eluting stent vs. abciximab and bare-metal stent for acute myocardial infarction: a randomized trial. JAMA 2005; 293: 2109-17. 미소장
15 Randomized Trial of Sirolimus-Eluting Stent Versus Bare-Metal Stent in Acute Myocardial Infarction (SESAMI) 네이버 미소장
16 Drug-eluting versus bare metal stents in patients with st-segment-elevation myocardial infarction: eight-month follow-up in the Drug Elution and Distal Protection in Acute Myocardial Infarction (DEDICATION) trial. 네이버 미소장
17 Paclitaxel-eluting stents versus bare-metal stents in acute myocardial infarction. 네이버 미소장
18 Two-year clinical follow-up after sirolimus-eluting versus bare-metal stent implantation assisted by systematic glycoprotein IIb/IIIa Inhibitor Infusion in patients with myocardial infarction: results from the STRATEGY study. 네이버 미소장
19 Drug-eluting or bare-metal stents for acute myocardial infarction. 네이버 미소장
20 Long-Term outcome of drug-eluting stents compared with bare metal stents in ST-segment elevation myocardial infarction: results of the paclitaxel- or sirolimus-eluting stent versus bare metal stent in Primary Angioplasty (PASEO) Randomized Trial. 네이버 미소장
21 Drug-eluting stents for acute myocardial infarction. 네이버 미소장
22 Use of drug-eluting stents in acute myocardial infarction: a systematic review and meta-analysis. 네이버 미소장
23 Coronary in-stent restenosis—predictors, treatment and prevention 네이버 미소장
24 One-year clinical results with the slow-release, polymer-based, paclitaxel-eluting TAXUS stent: the TAXUS-IV trial. 네이버 미소장
25 Comparison of Effectiveness of Bare Metal Stents Versus Drug-Eluting Stents in Large (≥3.5 mm) Coronary Arteries 네이버 미소장
26 Quizhpe AR, Feres F, de Ribamar Costa J Jr, Abizaid A, Maldonado G, Costa R, Abizaid A, Cano M, Moreira AC, Staico R, Mattos LA, Tanajura LF, Chaves A, Centemero M, Sousa AM, Sousa JE. Drug-eluting stents vs. bare metal stents for the treatment of large coronary vessels. Am Heart J 2007; 154: 373-8. 미소장
27 Na JO, Kim JW, Choi CU, Choi UJ, Shin SY, Lim HE, Kim EJ, Rha SW, Park CG, Seo HS, Oh DJ. Bare-metal stents versus drug-eluting stents in large (≥ 3.5 mm) single coronary artery: Angiographic and clinical outcomes at 6 months. J Cardiol 2009; 54: 108-14. 미소장
28 Pfisterer M, Brunner-La Rocca HP, Rickenbacher P, Hunziker P, Mueller C, Nietlispach F, Leibundgut G, Bader F, Kaiser C; BASKET. Long-term benefit-risk balance of drug-eluting vs. bare-metal stents in daily practice: does stent diameter matter? Three-year follow-up of BASKET. Eur Heart J 2009; 30: 16-24. 미소장
29 Prevention of Restenosis by Systemic Drug Therapy 네이버 미소장
30 Effects of combined therapy with ezetimibe plus simvastatin after drug-eluting stent implantation in a porcine coronary restenosis model. 소장

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