본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색
결과 내 검색 동의어 포함
결과 내 검색 동의어 포함

-

초록보기

Purpose: This study was conducted to investigate the immune responses of children with moderate and severe novel influenza A virus (H1N1) pneumonia, and to compare their clinical and immunological findings with those of control subjects. Methods: Thirty-two admitted patients with H1N1 pneumonia were enrolled in the study. The clinical profiles, humoral and cell-mediated immune responses of the 16 H1N1 pneumonia patients who were admitted to the pediatric intensive care unit (severe pneumonia group),16 H1N1 pneumonia patients admitted to the pediatric general ward (moderate pneumonia group) and 13 control subjects (control group)were measured. Results: Total lymphocyte counts were significantly lower in patients with H1N1 pneumonia than in the control group (P=0.02). The number of CD4+ T lymphocytes was significantly lower in the severe pneumonia group (411.5±253.5/μL) than in the moderate pneumonia (644.9±291.1/μL, P=0.04) and control (902.5±461.2/μL, P=0.01) groups. However, the number of CD8+ T lymphocytes was significantly higher in the severe pneumonia group (684.2±420.8/μL) than in the moderate pneumonia (319.7±176.6/μL, P=0.02) and control (407.2±309.3/μL, P=0.03) groups. The CD4+/CD8+ T lymphocytes ratio was significantly lower in the severe pneumonia group (0.86±0.24) than in the moderate pneumonia (1.57±0.41, P=0.01) and control (1.61±0.49, P=0.01) groups. The serum levels of immunoglobulin G, immunoglobulin M and immunoglobulin E were significantly higher in the severe pneumonia group than in the 2 other groups. Conclusion: The results of this study suggest that increased humoral immune responses and the differences in the CD4+ and CD8+ T lymphocyte profiles, and imbalance of their ratios may be related to the severity of H1N1 pneumonia in children.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Congenital heart disease in the newborn requiring early intervention Sin Weon Yun pp.183-191

Respiratory syncytial virus infection in children with congenital heart disease :global data and interim results of Korean RSV-CHD survey Jo Won Jung pp.192-196

Respiratory syncytial virus prevention in children with congenital heart disease :who and how? Nam Kyun Kim ,Jae Young Choi pp.197-200

(A)study on the menstruation of Korean adolescent girls in Seoul Jin Chul Lee ,Byung Keun Yu ,Jung Hye Byeon ,Kee-Hyoung Lee ,Jung Hye Min ,Sang Hee Park pp.201-206

CD4+/CD8+ T lymphocytes imbalance in children with severe 2009 pandemic influenza A(H1N1) pneumonia Ji Eun Kim ,Siegfried Bauer ,Kyong Suk La ,Kee Hyoung Lee ,Ji Tae Choung ,Kyoung Ho Roh ,Chang Kyu Lee ,Young Yoo pp.207-211

Discordant findings of dimercaptosuccinic acid scintigraphy in children with multi-detector row computed tomography-proven acute pyelonephritis Jeongmin Lee ,Duck Geun Kwon ,Se Jin Park ,Ki-Soo Pai pp.212-218

(A)case of McKusick-Kaufman syndrome Se-Hyung Son ,Yoon Joo Kim ,Eun Sun Kim ,Ee-Kyung Kim ,Han-Suk Kim ,Beyong Il Kim ,Jung-Hwan Choi pp.219-223

(A)sclerosing stromal tumor of the ovary with masculinization in a premenarchal girl Soo Min Park ,Young Nam Kim ,Young Jong Woo ,Ho Sun Choi ,Ji Shin Lee ,Suk Hee Heo ,Chan Jong Kim pp.224-227

참고문헌 (19건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Chan M. World now at the start of 2009 influenza pandemic [Internet]. Geneva: World Health Organization; c2011 [cited 2011 Mon Date]. Available from: http://www.who.int/mediacentre/news/statements/2009/ h1n1_pandemic_phase6_20090611/en/index.html. 미소장
2 Novel influenza A(H1N1) in a pediatric health care facility in New York City during the first wave of the 2009 pandemic. 네이버 미소장
3 Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans 네이버 미소장
4 Pneumonia and respiratory failure from swine-origin influenza A (H1N1) in Mexico. 네이버 미소장
5 Factors associated with death or hospitalization due to pandemic 2009 influenza A(H1N1) infection in California. 네이버 미소장
6 Cui W, Zhao H, Lu X, Wen Y, Zhou Y, Deng B, et al. Factors associated with death in hospitalized pneumonia patients with 2009 H1N1 influenza in Shenyang, China. BMC Infect Dis 2010;10:145. 미소장
7 Effect of the novel influenza A (H1N1) virus in the human immune system. 네이버 미소장
8 Development of Effective Vaccines against Pandemic Influenza 네이버 미소장
9 Cytotoxic T cell effector and memory function in viral immunity. 네이버 미소장
10 Lung pathology in fatal novel human influenza A (H1N1) infection. 네이버 미소장
11 Cellular immunity and lung injury in respiratory virus infection. 네이버 미소장
12 A practical guide for the diagnosis and treatment of pediatric pneumonia. 네이버 미소장
13 Human lymphocyte apoptosis after exposure to influenza A virus. 네이버 미소장
14 Avian influenza A (H5N1) in 10 patients in Vietnam. 네이버 미소장
15 Human disease from influenza A (H5N1), Thailand, 2004. 네이버 미소장
16 Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virus. 네이버 미소장
17 Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model. 네이버 미소장
18 An analysis of the normal ranges of lymphocyte subpopulations in children age 5-13 years 네이버 미소장
19 Pediatric hospitalizations associated with 2009 pandemic influenza A (H1N1) in Argentina. 네이버 미소장

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차