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Background/Aims: There is an ongoing debate on the relationship between gastric fundic gland polyps and increased incidence of colorectal neoplasia in Caucasians. However, there was no report on the relationship between gastric fundic gland polyp and colorectal neoplasia in Korea. The aim of this study was to identify the characteristics of gastric fundic gland polyps and whether a relationship exists between fundic gland polyps and colorectal neoplasia in Korean population.

Methods: Persons who underwent an esophagogastroduodenoscopy and colonoscopy from 1992 to 2007 at the Health Promotion Center of Incheon St. Mary’s Hospital, The Catholic University of Korea were reviewed retrospectively. The relationship between gastric fundic gland polyps and colorectal neoplasia were analyzed.

Results: Among 22,451 subjects, fundic gland polyps were found in 328 subjects (1.5%). Fundic gland polyps were more common in women than in men (odds ratio of 6.25; 95% CI of 4.68-8.34). The odds ratios for colorectal neoplasia in all subjects with gastric fundic gland polyps were 0.56 (95% CI of 0.33-0.95) and men who were 50 years of age or older had an odds ratio of 2.81 (95% CI of 1.03-7.66) as compared to the control group. However, age and sex-adjusted odds ratios for all gastric fundic gland polyps were 0.73 (95% CI of 0.42-1.26), for men 1.78 (95% CI of 0.80-3.98), and for women 0.37 (95% CI of 0.16-0.87).

Conclusions: Surveillance colonoscopy in patients with fundic gland polyps can be performed in the same manner as general population in Korea.

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노화와 소화기 질환 :위장관 기능 변화를 중심으로 박경식 pp.3-8

노인 위암 환자의 임상적 및 병리적 특징과 수술 시행에 따른 생존율 차이 최주영 ,심기남 ,노선희 ,태정현 ,김성은 ,정혜경 ,김태헌 ,정성애 ,유권 ,문일환 pp.9-19

Gastric fundic gland polyps and their relationship to colorectal neoplasia in Koreans :a 16-year retrospective study Sun-Mee Hwang ,Byung-Wook Kim ,Hiun-Suk Chae ,Bo-In Lee ,Hwang Choi ,Jeong-Seon Ji ,Kyu-Yong Choi ,In-Sik Chung ,Lee-So Maeng pp.20-24

HBA DNA loss within 24 weeks predicts late viral breakthrough in chronic hepatitis B Seong Ran Jeon ,Jae Young Jang ,Soung Won Jeong ,Seung Hoon Park ,Sae Hwan Lee ,Sang Gyune Kim ,Young Koog Cheon ,Young Seok Kim ,Young Deok Cho ,Jong Ho Moon ,Hong Soo Kim ,Joon Seong Lee ,Boo Sung Kim pp.25-30

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췌장 종괴를 형성하고 스테로이드에 호전을 보인 2형 자가면역 췌장염 전연주 ,장재혁 ,이인석 ,이장은 ,정문경 ,정찬권 ,최명규 ,정인식 pp.53-57

폐 침범이 의심되는 자가면역 췌장염 방승민 ,박정엽 pp.58-60

염증성 장질환 환자에서 임신 중 Thiopurine 치료의 안전성 예병덕 pp.61-63

참고문헌 (17건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Carmack SW, Genta RM, Schuler CM, Saboorian MH. The current spectrum of gastric polyps: a 1-year national study of over 120,000 patients. Am J Gastroenterol 2009;104:1524-1532. 미소장
2 Gastric polyps: a retrospective analysis of 26,000 digestive endoscopies 네이버 미소장
3 Sporadic fundic gland polyps: common gastric polyps arising through activating mutations in the beta-catenin gene. 네이버 미소장
4 Gastric fundic gland polyps 네이버 미소장
5 Gastric glandular cysts--investigations into their genesis and relationship to colorectal epithelial tumors. 네이버 미소장
6 Jung A, Vieth M, Maier O, Stolte M. Fundic gland polyps (Elster's cysts) of the gastric mucosa. A marker for colorectal epithelial neoplasia? Pathol Res Pract 2002;198:731-734. 미소장
7 No Association Between Gastric Fundic Gland Polyps and Gastrointestinal Neoplasia in a Study of Over 100,000 Patients 네이버 미소장
8 Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: A risk factor for colon cancer 네이버 미소장
9 American College of Gastroenterology guidelines for colorectal cancer screening 2009 [corrected]. 네이버 미소장
10 Epidemiology of colorectal cancer in Asia. 네이버 미소장
11 Teichmann J, Weickert U, Riemann JF. Gastric fundic gland polyps and colonic polyps - is there a link, really? Eur J Med Res 2008;13:192-195. 미소장
12 Colorectal Neoplasm in Asymptomatic Average-risk Koreans: The KASID Prospective Multicenter Colonoscopy Survey. 소장
13 Prevalence of polyps in an autopsy series from areas with varying incidence of large-bowel cancer. 네이버 미소장
14 Gastric fundic gland polyps: a clinico-pathological study from North West Tasmania. 네이버 미소장
15 Gastric polyposis: onset during long-term therapy with omeprazole. 네이버 미소장
16 Torbenson M, Lee JH, Cruz-Correa M, et al. Sporadic fundic gland polyposis: a clinical, histological, and molecular analysis. Mod Pathol 2002;15:718-723. 미소장
17 Sporadic fundic gland polyps: clinico-pathologic features and associated diseases. 네이버 미소장

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