본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

목차보기

Contents

Association between toll-like Receptors/CD14 gene polymorphisms and inflammatory bowel disease in korean population / Eun Jung Kim ; Woo Chul Chung ; Kang-Moon Lee ; Chang Nyol Paik ; Sung Hoon Jung ; Bo In Lee ; Hiun Suk Chae ; Kyu Yong Choi 1

[요약] 1

INTRODUCTION 1

MATERIALS AND METHODS 1

Subjects 1

Classification 2

Polymorphism analysis 2

Statistical analysis 2

Ethics statement 2

RESULTS 3

Demographic characteristics of patients 3

TLR polymorphisms 3

CD 14 polymorphisms 3

DISCUSSION 4

REFERENCES 5

초록보기

The innate immune response in patients who develop inflammatory bowel disease (IBD) may be abnormal. However, the exact role of Toll-like receptors (TLRs) / CD14 gene in the pathogenesis of IBD has not been fully elucidated. We aimed to investigate the association between polymorphisms of TLR1, 2, 4, 6, and CD14 gene and susceptibility to IBD in Korean population. A total 144 patients of IBD (99 patients with ulcerative colitis, 45 patients with Crohn’s disease) and 178 healthy controls were enrolled. Using a PCR-RFLP, we evaluated mutations of TLR1 (Arg80Thr), TLR2 (Arg753Gln and Arg677Trp), TLR4 (Asp299Gly and Thr399Ile), TLR6 (Ser249Pro) genes and the -159 C/T promoter polymorphism of CD14 gene. No TLR polymorphisms were detected in Korean subjects. T allele and TT genotype frequencies of CD14 gene were significantly higher in IBD patients than in healthy controls. In subgroup analysis, T allelic frequency was higher in pancolitis phenotype of ulcerative colitis. In Korean population, the promoter polymorphism at -159 C/T of the CD14 gene is positively associated with IBD, both ulcerative colitis and Crohn’s disease.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Cellular toxicity of surfactants used as herbicide additives Ho-Yeon Song, Young-Hee Kim, Su-Jin Seok, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong pp.3-9

보기
Real-time nucleic acid sequence-based amplification to predict the clinical outcome of invasive aspergillosis Si-Hyun Kim, Chulmin Park, Eun-Young Kwon, Na-Young Shin, Jae-Cheol Kwon, Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo pp.10-15

보기
Prevalence of widespread pain and its influence on quality of life : population study in Korea Nam Han Cho, Inje Kim, Seung Hun Lim, Hyun Ah Kim pp.16-21

보기
Induction of remission is difficult due to frequent relapse during tapering steroids in Korean patients with polymyalgia rheumatica Hyoun-Ah Kim, Jisoo Lee, You-Jung Ha, Sang-Hyon Kim, Chan-Hee Lee, Hyo-Jin Choi, Han-Joo Baek, Mie Jin Lim, Won Park, Sungiae Choi … [et al.] pp.22-26

보기
LPS-induced migration of peritoneal B-1 cells is associated with upregulation of CXCR4 and increased migratory sensitivity to CXCL12 Hana Moon, Jae-Ghi Lee, Sang Hyuck Shin, Tae Jin Kim pp.27-35

보기
Optimal number of endoscopic biopsies in diagnosis of advanced gastric and colorectal cancer Yeowon Choi, Hyo Sun Choi, Woo Kyu Jeon, Byung Ik Kim, Dong Il Park, Yong Kyun Cho, Hong Joo Kim, Jung Ho Park, Chong Il Sohn pp.36-39

보기
Optimal baseline prostate-specific antigen level to distinguish risk of prostate cancer in healthy men between 40 and 69 years of age Kyung Kgi Park, Seung Hwan Lee, Young Deuk Choi, Byung Ha Chung pp.40-45

보기
Nodal stations and diagnostic performances of endobronchial ultrasound-guided transbronchial needle aspiration in patients with non-small cell lung cancer Byung Woo Jhun, Hye Yun Park, Kyeongman Jeon, Won-Jung Koh, Gee Young Suh, Man Pyo Chung, Hojoong Kim, O Jung Kwon, Joungho Han, Sang-Won Um pp.46-51

보기
APACHE II score, rather than cardiac function, may predict poor prognosis in patients with stress-induced cardiomyopathy Byung-Hyun Joe, Uk Jo, Hyun-Soo Kim, Chang-Bum Park, Hui-Jeong Hwang, Il-Suk Sohn, Eun-Sun Jin, Jin-Man Cho, Jeong-Hwan Park, Chong-Jin Kim pp.52-57

보기
Low cholesterol is associated with mortality from cardiovascular diseases : a dynamic cohort study in Korean adults Jong-Myon Bae, Yeong-Ja Yang, Zhong-Min Li, Yoon-Ok Ahn pp.58-63

보기
Lower residual renal function is a risk factor for depression and impaired health-related quality of life in Korean peritoneal dialysis patients Hayne Cho Park, Hajeong Lee, Jung Pyo Lee, Dong Ki Kim, Kook-Hwan Oh, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Curie Ahn, Yun Kyu Oh pp.64-71

보기
Association between toll-like receptors/CD14 gene polymorphisms and inflammatory bowel disease in Korean population Eun Jung Kim, Woo Chul Chung, Kang-Moon Lee, Chang Nyol Paik, Sung Hoon Jung, Bo In Lee, Hiun Suk Chae, Kyu Yong Choi pp.72-77

보기
Assessment of serologic immunity to diphtheria-tetanus-pertussis after treatment of Korean pediatric hematology and oncology patients Hyo Jin Kwon, Jae-Wook Lee, Nak-Gyun Chung, Bin Cho, Hack-Ki Kim, Jin Han Kang pp.78-83

보기
Ischemic stroke in rats enhances bone resorption in vitro Myung Eun Chung, Jong In Lee, Sun Im, Joo Hyun Park pp.84-88

보기
Collision of three histologically distinct endometrial cancers of the uterus Ki-Seok Jang, Won-Moo Lee, Young-Jae Kim, Sam-Hyun Cho pp.89-92

보기
Silicosis caused by chronic inhalation of snail shell powder Jae Woo Jung, Byung Ook Lee, Jae Hee Lee, Sung Woon Park, Bo Min Kim, Jae Chol Choi, Jong Wook Shin, In Won Park, Byoung Whui Choi, Jae Yeol Kim pp.93-95

보기
Early-onset childhood sarcoidosis with incidental multiple enchondromatosis Jong-Hwa Lee, Yeon-Jung Lim, Seunghun Lee, Kyung Bin Joo, Yun Young Choi, Chan-Kum Park, Young-Ho Lee pp.96-100

보기
Severe jaundice in two children with Kawasaki disease : a possible association with Gilbert syndrome Themistocles Karpathios, Maria Moustaki, Panagiotis Yiallouros, Fariba Sharifi, Achilleas Attilakos, Anna Papadopoulou, Andrew Fretzayas pp.101-103

보기
Migraine-like headache in a patient with complement 1 inhibitor deficient hereditary angioedema Jin-Young Chung, Manho Kim pp.104-106

보기
Correlation of DEFA1 gene copy number variation with intestinal involvement in Behcet's disease Joong Kyong Ahn, Hoon-Suk Cha, Jaejoon Lee, Chan Hong Jeon, Eun-Mi Koh pp.107-109

보기
Foodborne Eosinophilia due to Visceral Larva Migrans : A Disease Abandoned 임재훈 pp.1-2

참고문헌 (28건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Molecular epidemiology: recent advances and future directions 네이버 미소장
2 Familial Crohn's disease in single or multiple first-degree relatives. 네이버 미소장
3 The genetics of inflammatory bowel disease 네이버 미소장
4 Genome-Wide Scanning in Inflammatory Bowel Diseases 네이버 미소장
5 Toll-like receptors in the induction of the innate immune response. 네이버 미소장
6 Toll-like receptors and their signaling mechanisms. 네이버 미소장
7 Evaluation of CD14 in host defence 네이버 미소장
8 Effects of CD14-159 C/T polymorphism on CD14 expression and the balance between proinflammatory and anti-inflammatory cytokines in whole blood culture. 네이버 미소장
9 A polymorphism in the CD14 gene is associated with Crohn disease. 네이버 미소장
10 Gazouli M, Mantzaris G, Kotsinas A, Zacharatos P, Papalambros E, Archimandritis A, Ikonomopoulos J, Gorgoulis VG. Association between polymorphisms in the Toll-like receptor 4, CD14, and CARD15/NOD2 and inflammatory bowel disease in the Greek population. World J Gastroenterol 2005; 11: 681-5. 미소장
11 Polymorphisms of CARD15/NOD2 and CD14 genes in New Zealand Crohn's disease patients. 네이버 미소장
12 Ulcerative colitis is associated with a promoter polymorphism of lipopolysaccharide receptor gene, CD14. 네이버 미소장
13 Polymorphisms of CD14 gene and TLR4 gene are not associated with ulcerative colitis in Chinese patients. 네이버 미소장
14 Lack of association of the CD14 promoter polymorphism--159C/T with Caucasian inflammatory bowel disease. 네이버 미소장
15 Genetic polymorphisms of CD14 and Toll-like receptor-2 (TLR2) in patients with ulcerative colitis. 네이버 미소장
16 Incidence and prevalence of ulcerative colitis in the Songpa-Kangdong district, Seoul, Korea, 1986–1997 네이버 미소장
17 Gasche C, Scholmerich J, Brynskov J, D’Haens G, Hanauer SB, Irvine EJ, Jewell DP, Rachmilewitz D, Sachar DB, Sandborn WJ, Sutherland LR. A simple classification of Crohn’s disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998. Inflamm Bowel Dis 2000; 6: 8-15. 미소장
18 European evidence based consensus on the diagnosis and management of Crohn's disease: special situations. 네이버 미소장
19 The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. 네이버 미소장
20 European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis. 네이버 미소장
21 The role of bacterial infection in the pathogenesis of inflammatory bowel disease. 네이버 미소장
22 Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis 네이버 미소장
23 Lee J, Mo JH, Katakura K, Alkalay I, Rucker AN, Liu YT, Lee HK, Shen C, Cojocaru G, Shenouda S, Kagnoff M, Eckmann L, Ben-Neriah Y, Raz E. Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells. Nat Cell Biol 2006; 8: 1327-36. 미소장
24 Baumgart DC, Buning C, Geerdts L, Schmidt HH, Genschel J, Fiedler T, Gentz E, Molnar T, Nagy F, Lonovics J, Lochs H, Wiedenmann B, Nickel R, Witt H, Dignass A. The c.1-260C>T promoter variant of CD14 but not the c.896A>G (p.D299G) variant of toll-like receptor 4 (TLR4) genes is associated with inflammatory bowel disease. Digestion 2007; 76: 196-202. 미소장
25 Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. 네이버 미소장
26 Toll‐like receptor‐1, ‐2, and ‐6 polymorphisms influence disease extension in inflammatory bowel diseases 네이버 미소장
27 C(-260)-->T polymorphism in the promoter of the CD14 monocyte receptor gene as a risk factor for myocardial infarction. 네이버 미소장
28 Fighting infection: the role of lipopolysaccharide binding proteins CD14 and LBP. 네이버 미소장

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기