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Objective: The aim of this study is to elucidate the clinical characteristics of patients with spinal epidural abscess(SEA) and demonstrate the risk factors, treatments and neurologic outcomes.
Methods: We retrospectively reviewed the medical records and radiologic images of 35 patients admitted to our department with SEA between March 1987 and April 2011. While we performed decompressive laminectomy and abscess drainage on 19 patients (54.3%), and 16 patients (45.7%) initially received conservative therapy with antibiotics alone. Medical Research Council (MRC) scale was applied to estimate results objectively.
Results: The neurological outcome data showed improved MRC scale from 14 (40%) patients. 13 (37.1%) patients showed unchanged MRC scale and 8 (22.9%) patients revealed worsened MRC scale at the time of discharge. The patients with surgical treatment showed more improved MRC scale than the patients with conservative treatment and this was statistically significant (p=0.001) on univariate analysis. Initially, patients with decreased MRC scale and rapidly progressing neurological deficit underwent emergency surgery within 24 hours. Patients with intact MRC scale and minor neurological deficit received delayed surgery or conservative management with antibiotics. Among 19 patients those who experienced emergent operations within 24 hours showed better prognosis than those who underwent delayed operations after 24 hours.
Conclusion: Surgical treatment is the modality of choice in patients with SEA and urgent surgery especially is indicated in patients with neurological deficits. And early surgery is more effective in neurological improvements than delayed surgery and conservative management.| 번호 | 참고문헌 | 국회도서관 소장유무 |
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| 1 | Multilevel Epidural Abscess Formation with Paraplegia in a Healthy 33-Year-Old Man Caused by Staphylococcus aureus (MSSA) ![]() |
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| 2 | Ahl T, Hedstrom M, von Heijne A, Stiernstedt SH: Acute spinal epidural abscess without concurrent spondylodiscitis. Successful closed treatment in 10 cases. Acta Orthop Scand 70:199- 202, 1999 | 미소장 |
| 3 | Akalan N, lan T: Infection as a cause of spinal cord compression: A review of 36 spinal epidural abscess cases. Acta Neurochir (Wien) 142:17-23, 2000 | 미소장 |
| 4 | Curry WT Jr., Hoh BL, Amin-Hanjani S, Eskandar EN: Spinal epidural abscess: clinical presentation, management, and outcome. Surg Neurol 63:364-371, 2005 | 미소장 |
| 5 | Hadjipavlou AG, Katonis PK, Gaitanis IN, Muffoletto AJ, Tzermiadianos MN, Crow W: Percutaneous transpedicular disectomyand drainage in pyogenic spondylodiscitis. Eur Spine J 13:707-713, 2004 | 미소장 |
| 6 | Hematogenous pyogenic spinal infections and their surgical management. ![]() |
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| 7 | Surgical strategies for vertebral osteomyelitis and epidural abscess. ![]() |
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| 8 | Prognostic Factors of Pyogenic Spinal Infections | 소장 |
| 9 | Neurosurgery ![]() |
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| 10 | Title comparison of primary and secondary spinal epidural abscesses: a retrospective analysis of 29 cases ![]() |
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| 11 | Acute Panspinal Epidural Abscess | 소장 |
| 12 | Kim JS, Sung KH, Cho YW, Kim KH, Bae SD: Extensive Spinal Epidural Abscess: The Usefulness of Minimal Invasive Surgical Technique using Epidural Irrigation Catheter. Korean J Spine 8:221-224, 2011 | 미소장 |
| 13 | Kowalski TJ, Layton KF, Berbari EF, Steckelberg JM, Huddleston PM, Wald JT, et al: Follow-Up MR imaging in Patients with Pyogenic Spine Infections: Lack of Correlation with Clinical Features. A JNR Am J Neuroradiol 28:693-699, 2007 | 미소장 |
| 14 | Surgical Treatment of the Spontaneous Spinal Epidural Abscess | 소장 |
| 15 | Mann S, Schutze M, Sola S, Piek J: Nonspecific pyogenic spondylodiscitis: clinical manifestations, surgical treatment, and outcome in 24 patients. Neurosurg Focus 17:E3, 2004 | 미소장 |
| 16 | Muzii VF, Mariottini A, Zalaffi A, Carangelo BR, Palma L: Cervical spine epidural abscess: experience with microsurgical treatment in Eight cases. J Neurosurg Spine 5:392-397, 2006 | 미소장 |
| 17 | Two-stage Management for Vertebral Osteomyelitis and Epidural Abscess: Technical Note ![]() |
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| 18 | Nussbaum ES, Rigamonti D, Standiford H, Numaguchi Y, Wolf AL, Robinson WL: Spinal epidural abscess: a report of 40 cases and review. Surg Neurol 38:225-231, 1992 | 미소장 |
| 19 | Single-stage debridement and instrumentation for pyogenic spinal infections. ![]() |
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| 20 | Epidural Spinal Infection ![]() |
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| 21 | Pyogenic spondylitis and epidural abscess distant from the site of continuous epidural block in a patient with postherpetic neuralgia ![]() |
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| 22 | Review of 10 Cases of Pyogenic Epidural Abscess of the Spine | 소장 |
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