대표어
한국학술지인용색인(NRF)
권호기사보기
| 기사명 | 저자명 | 페이지 | 원문 | 기사목차 |
|---|
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정보검색
소장정보 검색
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동의어 포함
초록보기
Background/Aims: This study assessed the antibiotic resistance organisms isolated from the blood and bile of acute cholangitis and evaluated risk factors associated with them and their impact on clinical outcomes.
Methods: The identities and antibiotic resistance profiles of bacteria isolated from 433 cases of acute cholangitis from 346 patients were analyzed. Risk factors and the outcomes of patients infected with them were assessed.
Results: Microorganisms were isolated from 266 of 419 blood cultures and 256 of 260 bile cultures. Isolates from bile and blood were identical in 71% of the cases. A total of 20 extended spectrum-β-lactamase (ESBL)-producers and 4 carbapenemase-producing organisms were isolated from blood, and 34 ESBL-producers and 13 carbapenemase-producers were isolated from bile. Sixty-four (14.8%) cases were infected with any one of these bacteria isolated from blood or bile. Risk factors associated with them in blood were nosocomial infection and prior biliary intervention. In bile, indwelling biliary device was a risk factor associated with them. Antibiotic-resistant bacteria were associated with mortality, independent of other prognostic factors.
Conclusions: ESBL or carbapenemase-producing bacteria were frequently isolated in acute cholangitis patients especially with prior biliary intervention and nosocomial infection. Isolation of antibiotic-resistant bacteria was an independent risk factor of mortality.권호기사
참고문헌 (25건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Ascending infection of the biliary tract after surgical sphincterotomy and biliary stenting  |
미소장 |
| 2 | Bornman PC, van Beljon JI, Krige JE. Management of cholangitis. J Hepatobiliary Pancreat Surg 2003;10:406-414. | 미소장 |
| 3 | Microbiology of bile in patients with cholangitis or cholestasis with and without plastic biliary endoprosthesis |
미소장 |
| 4 | Emergence of antibiotic resistance during therapy for infections caused by Enterobacteriaceae producing AmpC beta-lactamase: implications for antibiotic use. |
미소장 |
| 5 | Emergence of Enterobacteriaceae producing extended-spectrum beta-lactamases (ESBLs) in the community. |
미소장 |
| 6 | Community infections caused by extended-spectrum beta-lactamase-producing Escherichia coli. |
미소장 |
| 7 | Hawkey PM. Prevalence and clonality of extended-spectrum beta-lactamases in Asia. Clin Microbiol Infect 2008;14 Suppl 1:159-165. | 미소장 |
| 8 | Predictors of mortality in patients with bloodstream infections caused by extended-spectrum-beta-lactamase-producing Enterobacteriaceae: importance of inadequate initial antimicrobial treatment. |
미소장 |
| 9 | Risk factors of carbapenem-resistant Klebsiella pneumoniae infections: a matched case control study. |
미소장 |
| 10 | Heo JH, Lee JH, Lee MY, et al. Bacterial identification in bile and blood of patients with acute cholangitis from benign and malignant bile duct obstruction. Korean J Gastroenterol 2002;40:53-59. | 미소장 |
| 11 | Microbiology of choledochal bile in patients with choledocholithiasis admitted to a tertiary hospital. |
미소장 |
| 12 | Resistant pathogens in biliary obstruction: importance of cultures to guide antibiotic therapy. |
미소장 |
| 13 | Biliary tract infection and bacteraemia: presentation, structural abnormalities, causative organisms and clinical outcomes. |
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| 14 | Multidrug resistance of isolated microorganisms in occluded bile duct stents. |
미소장 |
| 15 | Microbiologic Study of the Bile Culture and Antimicrobial Susceptibility in Patients with Biliary Tract Infection | 소장 |
| 16 | Wada K, Takada T, Kawarada Y, et al. Diagnostic criteria and severity assessment of acute cholangitis: Tokyo guidelines. J Hepatobiliary Pancreat Surg 2007;14:52-58. | 미소장 |
| 17 | Wikler MA; Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing. Sixteenth Informational Supplement. Wayne: Clinical and Laboratory Standards Institute; 2006. | 미소장 |
| 18 | Sung JY, Costerton JW, Shaffer EA. Defense system in the biliary tract against bacterial infection. Dig Dis Sci 1992;37:689-696. | 미소장 |
| 19 | Routine bile collection for microbiological analysis during cholangiography and its impact on the management of cholangitis |
미소장 |
| 20 | Tanaka A, Takada T, Kawarada Y, et al. Antimicrobial therapy for acute cholangitis: Tokyo guidelines. J Hepatobiliary Pancreat Surg 2007;14: 59-67. | 미소장 |
| 21 | Hawkey PM, Jones AM. The changing epidemiology of resistance. J Antimicrob Chemother 2009;64 Suppl 1:i3-i10. | 미소장 |
| 22 | Evolution of antimicrobial susceptibility patterns of aerobic and facultative gram-negative bacilli causing intra-abdominal infections: results from the SMART studies 2003-2007. |
미소장 |
| 23 | Risk factors for the acquisition of carbapenem-resistant Escherichia coli among hospitalized patients |
미소장 |
| 24 | Extended-spectrum beta-lactamase-producing organisms. |
미소장 |
| 25 | Mortality and delay in effective therapy associated with extended-spectrum beta-lactamase production in Enterobacteriaceae bacteraemia: a systematic review and meta-analysis. |
미소장 |
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