대표어
한국학술지인용색인(NRF)
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초록보기
This study investigated the cognition-related effects on antioxidant activities, γ-aminobutyric acid (GABA) contents, and AChE inhibitory activities in ethanol extracts from Zingiber officinale Rosc. (Korea), Curcuma longa L. (Korea), Curcuma longa L. (Myanmar), and Curcuma aromatica Salisb. (India). These extracts were investigated to determine the relationships among total polyphenols as well as DPPH and ABTS radical scavenging activities, GABA contents, and acetylcholinestrase (AChE) inhibitory activity. For the results, C. longa L. from Myanmar exhibited the highest contents of curcumin (97.1 μg/mg), total polyphenols (98.4 μg/mg), and GABA (1.31 μg/mg), as well as the strongest radical scavenging activities and AChE inhibitory activity. In addition, C. aromatica Salisb from India, which had the highest total polyphenol content (98.4 μg/mg) and strongest radical scavenging activities, exhibited relatively high AChE inhibitory activity similar to that of C. longa L. from Myanmar. On the other hand, Z. officinale Rosc. and C. longa L. from Korea showed low contents of curcumin (12.2 μg/mg) and polyphenols (85.7 μg/mg), as well as low AChE inhibitory activities. However, we could detect 1.11 μg/mg of GABA in these extracts, which was similar to that of C. longa L. from Myanmar. Therefore, GABA content was not correlated with AChE inhibitory activity. Based on the results, AChE inhibitory activity is highly correlated with polyphenol contents in Zingibearceae family. Overall, among the Zingiberaceae tested, C. longa L. from Myanmar might be a strong candidate as a cognitive-enhancing ingredient.
권호기사
참고문헌 (44건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Biochemical and neurobehavioral profile of CHF2819, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease.  |
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| 2 | Oh SK. 2005. Neurotransmetters and Brain Disease. Shinil Books company, Seoul, Korea. p 345-364. | 미소장 |
| 3 | Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa. |
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| 4 | Inhibitory effect of ursolic acid purified from Origanum majorana L on the acetylcholinesterase. | 소장 |
| 5 | Effect of a polyphenol-rich wild blueberry extract on cognitive performance of mice, brain antioxidant markers and acetylcholinesterase activity. |
미소장 |
| 6 | Amenta F, Parnetti L, Gallai V, Wallin A. 2001. Treatment of cognitive dysfunction associated with Alzheimer’s disease with cholinergic precursors. Ineffective treatments or inappropriate approaches? Mech Ageing Dev 122: 2025- 2040. | 미소장 |
| 7 | Regulation of nicotinic acetylcholine receptor channel function by acetylcholinesterase inhibitors in rat hippocampal CA1 interneurons. |
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| 8 | Nicotine attenuates β -amyloid peptide-induced neurotoxicity, free radical and calcium accumulation in hippocampal neuronal cultures |
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| 9 | Oh SH, Kim SH, Moon YJ, Choi WG. 2002. Changes in the levels of γ-aminobutyric acid and some amino acids by application of a glutamic acid solution for the germination of brown rices. Korea J Biotechnol Bioeng 17: 49-53. | 미소장 |
| 10 | Higher accumulation of γ-aminobutyric acid induced by salt stress through stimulating the activity of diamine oxidases in Glycine max (L.) Merr. roots |
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| 11 | Lim SD, Kim KS. 2009. Effects and utilization of GABA. Korean J Dairy Sci Technol 27: 45-51. | 미소장 |
| 12 | Metabolism and functions of gamma-aminobutyric acid |
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| 13 | Ahn DG. 2000. Korean herbal flora. Kyohak Publishing Co., Seoul, Korea. p 568-569. | 미소장 |
| 14 | Effect of dietary curcumin and dibenzoylmethane on formation of 7,12-dimethylbenz[a]anthracene-induced mammary tumors and lymphomas/leukemias in Sencar mice. |
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| 15 | Chainani-Wu N. 2003. Safety and anti-inflammatory activity of curcumin: a component of turmeric (Curcuma longa). J Altern Complement Med 9: 161-168. | 미소장 |
| 16 | Antioxidative Property of Turmeric (Curcumae Rhizoma) Ethanol Extract | 소장 |
| 17 | Enhancement of Liver Function by Curcuma Extract on Acute Hepatotoxicity in Rat | 소장 |
| 18 | Jeong SH, CHang KS, Kim YJ. 2004. Optimization of curcumin extraction from turmeric (Curcuma longa L.) using supercritical fluid CO2. Food Engineering Progress 8: 47-52. | 미소장 |
| 19 | Physiological Effects of Curcumin Extracted by Supercritical Fluid from Turmeric (Curcuma longa L.) | 소장 |
| 20 | Inhibitory Effects of Some Herbal Extracts on the Acetylcholinesterase (AChE) In Vitro | 소장 |
| 21 | Folin O, Denis W. 1912. Phosphotungastic-phospho-molybdic compounds as color reagents. J Biol Chem 12: 239- 249. | 미소장 |
| 22 | Antioxidant Determinations by the Use of a Stable Free Radical |
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| 23 | Antioxidant activity applying an improved ABTS radical cation decolorization assay. |
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| 24 | Zhang G, Bown AW. 1996. The rapid determination of γ- aminobutyric acid. Phytochemistry 44: 1007-1009. | 미소장 |
| 25 | A new and rapid colorimetric determination of acetylcholinesterase activity. |
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| 26 | PACIFIC STEELHEAD (ONCORHYNCHUS MYKISS) EXPOSED TO CHLORPYRIFOS: BENCHMARK CONCENTRATION ESTIMATES FOR ACETYLCHOLINESTERASE INHIBITION |
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| 27 | Lee TY, Lee KC, Chen SY, Chang HH. 2009. 6-Gingerol inhibits ROS and iNOS through the suppression of PKC-α and NF-κB pathways in lipopolysaccharide-stimulated mouse macrophages. Biochem Biophys Res Commun 382: 134-139. | 미소장 |
| 28 | Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol |
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| 29 | Wu H, Hsieh MC, Lo CY, Liu CB, Sang S, Ho CT, Pan MH.2010. 6-Shogaol is more effective than 6-gingerol and curcuminin inhibiting 12-O-tetradecanoylphorbol 13-acetateinducedtumor promotion in mice. Mol Nutr Food Res 54:1296-12306. | 미소장 |
| 30 | Jeong SH, Chang KS, Kim YJ. 2004. Optimization of curcumin extraction from turmeric (Curcuma longa L.) using supercritical fluid CO2. Food Eng Progress 8: 47-52. | 미소장 |
| 31 | Choi HS. 1994. Lipid peroxidation and its nutritional significance. J Korean Soc Food Nutr 23: 867-878. | 미소장 |
| 32 | Pratt DE. 1992. Natural antioxidant from plant material. In Phenolic Compounds in Food and Their Effects on Health. American Chemical Society, Washington, DC, USA. p 54- 71. | 미소장 |
| 33 | Higasi GS. 2000. Appraisement of antioxidative activity from vegetables. J ap J Food Ind 57: 56-64. | 미소장 |
| 34 | Curcumin as "Curecumin": From kitchen to clinic |
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| 35 | Lipid peroxidation in aging brain and Alzheimer's disease. |
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| 36 | Oxidative stress in brain aging: Implications for therapeutics of neurodegenerative diseases |
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| 37 | Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials. |
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| 38 | Kang YH, Park YK, Oh SR, Moon KD. 1995. Studies on the physiological functionality of pine needle and mugwort extracts. Korean J Food Sci Technol 27: 978-984. | 미소장 |
| 39 | Total Polyphenol Contents and Antioxidant Activities of Methanol Extracts from Vegetables produced in Ullung Island | 소장 |
| 40 | The Antioxidant Activities of the Some Commercial Teas | 소장 |
| 41 | The Metabolism and Functions of γ-Aminobutyric Acid |
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| 42 | Synaptic interactions between GABAergic neurons and trigeminothalamic cells in the rat trigeminal nucleus caudalis. |
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| 43 | Continuous Production of γ-aminobutyric Acid by Immobilization of Lactobacillus brevis | 소장 |
| 44 | Acetylcholinesterase in Alzheimer's disease. |
미소장 |
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