국내기사
Bone subtraction 3-dimension CT angiography using 64-slice multidetector CT for the evaluation of steno-occlusive intra- and extracranial vascular diseases : comparison with digital subtraction angiography
저자명
Sung Eun Park, Dae Seob Choi, Hwa Seon Shin, Jin Jong You, Mi Jung Park, Jae Min Cho, Ho Cheol Choi, Seungnam Son, Nack-Cheon Choi, Jae Wook Ryu
목적: 두개 내외의 협착과 폐쇄성 혈관질환의 평가에 있어 골감산 3차원 CT angiography (이하 CTA)의 유용성을 평가하고자 하였다. 대상과 방법: 64채널 다중검출기 CT를 이용한 CTA와 digital subtraction angiography (이하 DSA)를 모두 시행한 56명의 환자를 대상으로 하였다. 골감산 CTA (이하 BSCTA)를 위하여 조영 전 CT와 조영증강 CTA 데이터를 얻었다. 각 혈관분절의 협착 정도를 분석하여 5단계로 분류하였으며, DSA 결과를 기준으로 CTA 영상을 비교하였다. 결과: 두개 외 혈관의 경우 370개의 혈관분절을 분석하였고, 이 중 359(97.0%)개의 분절에서 CTA와 DSA 결과가 일치하였고 통계적으로 유의한 일치도를 보였다(Rs = 0.974). 50% 이상의 협착을 진단하는 데 있어 CTA는 100%, 98.2%, 98.6%의 민감도, 특이도, 진단적 정확도를 보였다. 두개 혈관의 경우 1029개의 분절을 분석하였는데, 이 중 966(93.9%)개의 분절에서 CTA와 DSA 결과가 일치하였고 통계적으로 유의하였다(Rs = 0.880). 50% 이상의 협착을 진단하는 데 있어 CTA의 민감도, 특이도, 진단적 정확도는 각각 100%, 95.8%, 96.0%였다. CTA와 DSA 결과가 일치하지 않았던 74개 분절은 모두 CTA에서 협착의 정도를 과대 평가하였다. 결론: 두개 내외의 협착과 폐쇄성 혈관질환의 평가에 있어 BSCTA는 DSA에 필적할만한 결과를 보였다. 그러나 석회화를 동반한 병변의 경우 협착 정도가 CTA에서 과대평가되는 경향을 보였다.
Purpose: To investigate the efficacy of bone subtraction CT angiography (BSCTA) for the evaluation of steno-occlusive intra- and extracranial vascular diseases. Materials and Methods: Fifty-six patients were examined using 64-slice multidetector CT and digital subtraction angiography (DSA). For BSCTA, both nonenhanced CT and enhanced CT angiography (CTA) data sets were obtained. The stenotic degree of each vascular segment was assessed and classified into 5 grades. With DSA as the standard, CTA images were compared. Results: For the evaluation of the extracranial vessels, 370 arterial segments were analyzed, and the stenotic degree revealed by CTA and DSA agreed in 359 (97.0%). There was a significant correlation between CTA and DSA (Rs = 0.974). For depiction of ≥ 50% stenosis, the sensitivity, specificity, and diagnostic accuracy of BSCTA were 100%, 98.2%, and 98.6%, respectively. For the intracranial arteries, 1029 segments were analyzed, and CTA agreed with DSA in 966 (93.9%). There was a significant correlation between CTA and DSA for stenotic degree (Rs = 0.880). For the depiction of ≥ 50% stenosis, the sensitivity, specificity, and diagnostic accuracy of CTA were 100%, 95.8%, and 96.0%, respectively. In all 74 segments of disagreement, the degree of stenosis was overestimated on CTA. Conclusion: BSCTA is comparable to DSA for the evaluation of steno-occlusive intra- and extracranial vascular diseases. However, the stenotic degree tends to be overestimated on BSCTA, especially in cases of wall calcifications.
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