본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

초록보기

In this study, we investigated the effect of methanolic extract isolated from the root of Lycoris aurea (LA) on the growth of cancer cells and the tube formation activity of endothelial cells. Various cancer cells were treated with LA at doses of 0.3, 1, 3, 10 or 30 μg/ml and LA significantly suppressed the growth of several cancer cell lines, including ACHN, HCT-15, K-562, MCF-7, PC-3 and SK-OV-3, in a dose-dependent manner. We also found that LA induced cell cycle arrest at G2/M phase in ACHN renal cell adenocarcinoma cells. Further study demonstrated that LA concentration-dependently inhibited the tube formation, which is a widely used in vitro model of reorganization stage of angiogenesis, in human umbilical vein endothelial cells. Collectively, these results show that LA inhibits the growth of cancer cells and tube formation of endothelial cells and the growth-inhibitory effect of LA might be mediated, at least in part, by blocking cell cycle progression.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Skin sensitization study of Bee Venom(Apis mellifera L.) in guinea pigs Sang Mi Han, Gwang Gill Lee, Kyun Kyu Park pp.1-4

Synthetic prion peptide 106-126 resulted in an increase matrix metalloproteinases and inflammatory cytokines from rat astrocytes and microglial cells Kibeum Song, Ji-Young Na, Myung-Hoon Oh, Sokho Kim, Young-Ha Kim, Byung-Yong Park, Gi-Wook Shin, Bumseok Kim, Myungjo You, Jungkee Kwon pp.5-9

Mouse single oral dose toxicity test of bupleuri radix aqueous extracts Kyung-Hu Kim, Cheol-Ou Gam, Seong-Hun Choi, Sae-Kwang Ku pp.11-18

Involvement of Caenohabditis elegans MAPK signaling pathways in oxidative stress response induced by silver nanoparticles exposure Ji-Yeon Roh, Hyun-Jeong Eom, Jinhee Choi pp.19-24

Acute pulmonary toxicity and body distribution of inhaled metallic silver nanoparticles Jung-Taek Kwon, Arash Minai-Tehrani, Soon-Kyung Hwang, Ji-Eun Kim, Ji-Young Shin, Kyeong-Nam Yu, Seung-Hee Chang, Dae-Seong Kim, Yong-Taek Kwon, In-Ja Choi … [et al.] pp.25-31

Methanolic extract isolated from root of Lycoris aurea inhibits cancer cell growth and endothelial cell tube formation in vitro Moo Rim Kang, Chang Woo Lee, Jieun Yun, Soo Jin Oh, Song-Kyu Park, Kiho Lee, Hwan Mook Kim, Sang-Bae Han, Hyoung-Chin Kim, Jong Soon Kang pp.33-38

Suppressive effect of zinc on the formation of colonic preneoplastic lesions in the mouse fed high levels of dietary iron Hyunji Park, Bong Su Kang, Dang Young Kim, Ja Seon Yoon, Jae-Hwang Jeong, Sang Yoon Nam, Young Won Yun, Jong-Soo Kim, Beom Jun Lee pp.39-49

Thesafety evaluation of a potent angiogenic activator, synthetic peptide(SFKLRY-NH₂) for the skin application Dong Ha Kim, Yun Young Lim, Hyeong Mi Kim, So Young Kim, Beom Joon Kim, Sung-Gil Park, Taehoon Lee, Soo-Muk Cho pp.51-56

Thetoxicity and anti-cancer activity of the hexane layer of Melia azedarach L. var. japonica Makino's bark extract Hyun Woo Kim, Se Chan Kang pp.57-65

Toxicological investigation of radioactive uranium in seawater Suw Young Ly, Jeong Mi Bae, Jin Kim pp.67-71

참고문헌 (20건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Anand, P., Kunnumakkara, A.B., Sundaram, C., Harikumar, K.B., Tharakan, S.T., Lai, O.S., Sung, B. and Aggarwal, B.B. (2008). Cancer is a preventable disease that requires major lifestyle changes. Pharm. Res., 25, 2097-2116. 미소장
2 Attenuation of multi-targeted proliferation-linked signaling by 3,3'-diindolylmethane (DIM): From bench to clinic 네이버 미소장
3 First report of a glutamine-rich antifungal peptide with immunomodulatory and antiproliferative activities from family Amaryllidaceae 네이버 미소장
4 Gastroenterologists Need to Address Anal Dysplasia Screening in High-Risk Populations 네이버 미소장
5 Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on the proliferation and cord formation of bovine capillary endothelial cells within collagen gels. 네이버 미소장
6 Lycorine sensitizes CD40 ligand-protected chronic lymphocytic leukemia cells to bezafibrate- and medroxyprogesterone acetate-induced apoptosis but dasatanib does not overcome reported CD40-mediated drug resistance. 네이버 미소장
7 Fibroblast growth factor signalling controls successive cell behaviours during mesoderm layer formation in Drosophila. 네이버 미소장
8 DNA damage-triggered apoptosis: critical role of DNA repair, double-strand breaks, cell proliferation and signaling 네이버 미소장
9 Rapid Flow Cytofluorometric Analysis of Mammalian Cell Cycle by Propidium Iodide Staining 네이버 미소장
10 Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an investigation of structure-activity relationship and mechanistic insight. 네이버 미소장
11 Apoptosis induced by lycorine in KM3 cells is associated with the G0/G1 cell cycle arrest. 네이버 미소장
12 Effects of lycorine on HL-60 cells via arresting cell cycle and inducing apoptosis 네이버 미소장
13 Apoptosis of HL-60 cells induced by extracts from Narcissus tazetta var. chinensis 네이버 미소장
14 Lycorine induces apoptosis and down-regulation of Mcl-1 in human leukemia cells 네이버 미소장
15 Malumbres, M. and Barbacid, M. (2009). Cell cycle, CDKs and cancer: a changing paradigm. Nat. Rev. Cancer, 9, 153-166 미소장
16 Mathematical modelling of dynamic adaptive tumour-induced angiogenesis: Clinical implications and therapeutic targeting strategies 네이버 미소장
17 Morales, C.P., Souza, R.F. and Spechler, S.J. (2002). Hallmarks of cancer progression in Barrett’s oesophagus. Lancet, 360, 1587- 1589. 미소장
18 Genetic instability in cancer cells by impaired cell cycle checkpoints. 네이버 미소장
19 Siegel, R., Ward, E., Brawley, O. and Jemal, A. (2011). Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA. Cancer J. Clin., 61, 212-236. 미소장
20 Tsuda, H., Ohshima, Y., Nomoto, H., Fujita, K., Matsuda, E., Iigo, M., Takasuka, N. and Moore, M.A. (2004). Cancer prevention by natural compounds. Drug Metab. Pharmacokinet., 19, 245- 263. 미소장

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기