한국학술지인용색인(NRF)
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목차
본태성 고혈압쥐(SHR)에서 현미 식물성스테롤의 혈압 및 지질 대사 개선 효과 / 홍경희 ; 김인환 ; 조은경 ; 안지윤 ; 하태열 1
Abstract 1
I. 서론 1
II. 연구 내용 및 방법 2
1. 실험재료 2
2. 실험동물 및 식이 2
3. 시료 채취 및 처리 2
4. 혈압 측정 3
5. 혈청 및 간조직의 지질 함량 측정 3
5. 혈청 중 AST, ALT 활성 측정 3
6. 간조직 및 신장의 과산화지질 함량 측정 3
7. 통계처리 3
III. 결과 및 고찰 3
1. 식이섭취량, 체중증가량 및 부고환지방 무게 3
2. 혈압의 변화 3
3. 혈청 및 간조직의 지질 함량 4
4. 혈청 AST 및 ALT의 활성 6
5. 간조직 및 신장의 TBARS 함량 6
IV. 요약 및 결론 7
감사의 글 7
■ 참고문헌 7
초록보기
This study was conducted to investigate the effects of brown rice and brown rice phytosterol on blood pressure and lipid levels in spontaneously hypertension rats (SHR). SHR were grouped according to blood pressure and fed either a control diet or experimental diets containing 50% brown rice powder or 5% brown rice phytosterol for 3 weeks. Body weight gain and epididymal fat weight were significantly reduced in the brown rice powder and brown rice phytosterol groups compared to control. Brown rice and brown rice phytosterol diets suppressed age-dependent increases in systolic blood pressure compared to control. In addition, brown rice and brown rice phytosterol diets decreased total lipid, triglyceride, and cholesterol levels in the liver, whereas serum HDL cholesterol increased. Lastly, brown rice phytosterol reduced TBARS contents in the kidney. These results suggest that brown rice and brown rice phytosterol exert antihypertensive effects that improve lipid metabolism in SHR.
권호기사
참고문헌 (42건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Rice bran fractions improve blood pressure, lipid profile, and glucose metabolism in stroke-prone spontaneously hypertensive rats.  |
미소장 |
| 2 | The Driselase-treated fraction of rice bran is a more effective dietary factor to improve hypertension, glucose and lipid metabolism in stroke-prone spontaneously hypertensive rats compared to ferulic acid. |
미소장 |
| 3 | Baker WL, Baker EL, Coleman CI. 2009. The effect of plant sterols or stanols on lipid parameters in patients with type 2 diabetes: a meta-analysis. Diabetes Res Clin Pract. 84(2):e33-37 | 미소장 |
| 4 | Changes in phytate content and phytase activity during the germination of some cereals |
미소장 |
| 5 | Billingsley M, Suria A. 1982. Effects of peripherally administered GABA and other amino acids on cardiopulmonary responses in anesthetized rats and dogs. Arch Int Pharmacod 255:131-140 | 미소장 |
| 6 | A rice bran oil diet increases LDL-receptor and HMG-CoA reductase mRNA expressions and insulin sensitivity in rats with streptozotocin/nicotinamide-induced type 2 diabetes. |
미소장 |
| 7 | Hypotensive Effect of Germinated Brown Rice on Spontaneously Hypertensive Rats | 소장 |
| 8 | Choi SW, Nam SH, Choi HC. 1996. Antioxidant activit of ethanolic extracts of rice brans. Food Biotechnol 5:305- 309 | 미소장 |
| 9 | Metabolic effects of plant sterols and stanols (Review) |
미소장 |
| 10 | Nitric oxide and its putative role in hypertension. |
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| 11 | High blood pressure-lowering and vasoprotective effects of milk products in experimental hypertension. |
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| 12 | Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). |
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| 13 | Plant stanol and sterol esters in prevention of cardiovascular diseases. |
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| 14 | A simple method for the isolation and purification of total lipides from animal tissues. |
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| 15 | Age-Related Changes in Blood Pressure, Hematological Values, Concentrations of Serum Biochemical Constituents and Weights of Organs in the SHR/Izm, SHRSP/Izm and WKY/Izm |
미소장 |
| 16 | Blood pressure reduced by whole grain diet containing barley or whole wheat and brown rice in moderately hypercholesterolemic men |
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| 17 | Endothelial function in hypercholesterolemic subjects: Effects of plant stanol and sterol esters |
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| 18 | Changes in nutraceutical lipid components of rice at different degrees of milling |
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| 19 | Angiotensin converting enzyme inhibitory activity in commercial fermented products. Formation of peptides under simulated gastrointestinal digestion. |
미소장 |
| 20 | Nutraceuticals, Vitamins, Antioxidants, and Minerals in the Prevention and Treatment of Hypertension |
미소장 |
| 21 | Blood-pressure-lowering effect of a novel fermented milk containing gamma-aminobutyric acid (GABA) in mild hypertensives. |
미소장 |
| 22 | Cardiovascular activity of milk casein-derived tripeptides and plant sterols in spontaneously hypertensive rats |
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| 23 | Modulation of plasma lipid levels and cholesterol kinetics by phytosterol versus phytostanol esters. |
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| 24 | Hypoglycemic effects of a phenolic acid fraction of rice bran and ferulic acid in C57BL/KsJ-db/db mice. |
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| 25 | Water-soluble rice bran enzymatic extract attenuates dyslipidemia, hypertension and insulin resistance in obese Zucker rats |
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| 26 | Components of blood pressure and risk of atherothrombotic brain infarction: the Framingham study. |
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| 27 | Dietary structured lipids and phytosteryl esters: blood lipids and cardiovascular status in spontaneously hypertensive rats. |
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| 28 | Koo BS, Lee JW. 2004. Effect of phytosterol treatment on plasma lipids and glucose in rats. Korean J Food Culture 19(4):429-434 | 미소장 |
| 29 | Effects of rice bran oil on the blood lipids profiles and insulin resistance in type 2 diabetes patients. |
미소장 |
| 30 | Lee MH, Son HS, Choi OK, OH SK, Kwon TB. 1994. Change physicochemical properties and mineral contents during buckwheat germination. Korean J Food Nutr 7:267-273 | 미소장 |
| 31 | Lee YR. 2004. Studies of functional foods using giant embryonic rice. Ph. D. degree thesis. Kyungpook National University. pp 159-164 | 미소장 |
| 32 | Supplementation of the black rice outer layer fraction to rabbits decreases atherosclerotic plaque formation and increases antioxidant status. |
미소장 |
| 33 | Plant stanol and sterol esters in prevention of cardiovascular diseases. |
미소장 |
| 34 | Miller NE. 1978. The evidence for the antiatherogenicity of high density lipoprotein in man. AOCS Annual Meeting st. Louis, Missouri | 미소장 |
| 35 | Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction |
미소장 |
| 36 | Interfacial oxidation of alpha-tocopherol and the surface properties of its oxidation products. |
미소장 |
| 37 | Rhee SJ, Choe WK. 1996. Effects of vitamin E and selenium on the antioxidantative defense system in STZ-induced diabetes rats. Korean J Nutr 29:22-31 | 미소장 |
| 38 | A Review on the Role of Phytosterols: New Insights Into Cardiovascular Risk |
미소장 |
| 39 | Short- and long-term effects of ferulic acid on blood pressure in spontaneously hypertensive rats |
미소장 |
| 40 | Factors related to the impact of antihypertensive treatment in antioxidant activities and oxidative stress by-products in human hypertension |
미소장 |
| 41 | Protective effect of colored rice over white rice on Fenton reaction-based renal lipid peroxidation in rats. |
미소장 |
| 42 | Anticancer effects of phytosterols |
미소장 |
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