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Purpose: Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of unknown etiology. The diagnosis of IGM requires that other granulomatous lesions in the breast be excluded. Tuberculous mastitis (TM) is also an uncommon disease that is often difficult to differentiate from IGM. The purpose of this study is to develop a new algorithm for the differential diagnosis and treatment of IGM and TM. Methods: Medical records of 68 patients (58 with IGM and 10 with TM) between July 1999 and February 2009 were retrospectively reviewed. Results: The mean age of the patients was 33.5 (IGM) and 40 (TM) years (p=0.018). The median follow-up was 84 months. Of the total 10 patients with TM, 5 patients had a history of pulmonary tuberculosis. The most common symptoms of the diseases were breast lump and pain. However, axillary lymphadenopathy was more seen in TM (50%) compared to IGM (20.6%) (p=0.048). TM showed more cancer-mimicking findings on radiologic study (p=0.028). In IGM, 48 patients (82.7%) underwent surgical wide excision and 21 patients (36.2%) were managed with corticosteroid therapy and antibiotics. All of the TM patients received antituberculosis medications and 9 patients (90%) underwent wide excision. The mean treatment duration was 2.8 months in IGM and 8.4 months in TM. Recurrence developed in 5 patients (8.6%) in IGM and 1 patient (10%) in TM. Conclusion: This study shows different characteristics between IGM and TM. The IGM patients were younger and had more mastalgia symptoms than the TM patients. Axillary lymphadenopathy was seen more often in TM patients. Half of the TM patients had pulmonary tuberculosis or tuberculosis lymphadenitis. Surgical wide excision might be both therapeutic and useful for providing an exact diagnosis.

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권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
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참고문헌 (27건) : 자료제공( 네이버학술정보 )

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번호 참고문헌 국회도서관 소장유무
1 Granulomatous mastitis: a lesion clinically simulating carcinoma. 네이버 미소장
2 Akcan A, Akyildiz H, Deneme MA, Akgun H, Aritas Y. Granulomatous lobular mastitis: a complex diagnostic and therapeutic problem. World J Surg 2006;30:1403-9. 미소장
3 Granulomatous mastitis: a report of seven cases. 네이버 미소장
4 Feasibility of Surgical Management in Patients with Granulomatous Mastitis 네이버 미소장
5 Elsiddig KE, Khalil EA, Elhag IA, Elsafi ME, Suleiman GM, Elkhidir IM, et al. Granulomatous mammary disease: ten years’ experience with fine needle aspiration cytology. Int J Tuberc Lung Dis 2003;7:365-9. 미소장
6 Granulomatous mastitis: mammographic and sonographic appearances. 네이버 미소장
7 Diagnosis and treatment of granulomatous mastitis. 네이버 미소장
8 Moore GE. Diagnosis and treatment of granulomatous mastitis. Br J Surg 1995;82:1002. 미소장
9 Ayeva-Derman M, Perrotin F, Lefrancq T, Roy F, Lansac J, Body G. Idiopathic granulomatous mastitis: review of the literature illustrated by 4 cases. J Gynecol Obstet Biol Reprod (Paris) 1999;28:800-7. 미소장
10 Belaabidia B, Essadki O, el Monsouri A, Squalli S. Idiopathic granulomatous mastitis: apropos of 8 cases and review of the literature. Gynecol Obstet Fertil 2002;30:383-9. 미소장
11 A clinicopthologic study of a rare clinical entity mimicking breast carcinoma: idiopathic granulomatous mastitis 네이버 미소장
12 The Role of Conservative Treatment in Idiopathic Granulomatous Mastitis 네이버 미소장
13 Idiopathic Granulomatous Mastitis: Case Report and Review of the Literature 네이버 미소장
14 Schelfout K, Tjalma WA, Cooremans ID, Coeman DC, Colpaert CG, Buytaert PM. Observations of an idiopathic granulomatous mastitis. Eur J Obstet Gynecol Peprod Biol 2001;97:260-2. 미소장
15 Granulomatous mastitis. 네이버 미소장
16 Idiopathic Granulomatous Mastitis: Time to Avoid Unnecessary Mastectomies 네이버 미소장
17 Diagnosis and treatment of granulomatous mastitis 네이버 미소장
18 Idiopathic granulomatous mastitis. A report of three cases and review of the literature. 네이버 미소장
19 Granulomatous mastitis: an uncommon cause of breast abscess. 네이버 미소장
20 Sakurai T, Oura S, Tanino H, Yoshimasu T, Kokawa Y, Kinoshita T, et al. A case of granulomatous mastitis mimicking breast carcinoma. Breast Cancer 2002;9:265-8. 미소장
21 The value of cytology in granulomatous mastitis: a report of 16 cases from Malaysia. 네이버 미소장
22 Granulomatous mastitis can mimic breast cancer on clinical, radiological or cytological examination: a cautionary tale 네이버 미소장
23 Cytology of Granulomatous Mastitis 네이버 미소장
24 Utility of fine‐needle aspiration in the diagnosis of granulomatous lesions of the breast 네이버 미소장
25 Granulomatous mastitis: a clinicopathological review of 26 cases 네이버 미소장
26 Idiopathic granulomatous mastitis masquerading as carcinoma of the breast: a case report and review of the literature. 네이버 미소장
27 Prednisone management of granulomatous mastitis. 네이버 미소장