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Background: The objective of this study was to evaluate a newly-developed EASYPREP liquid-based cytology method in cervicovaginal specimens and compare it with SurePath. Methods: Cervicovaginal specimens were prospectively collected from 1,000 patients with EASYPREP and SurePath. The specimens were first collected by brushing for SurePath and second for EASYPREP. The specimens of both methods were diagnosed according to the Bethesda System. Additionally, we performed to REBA HPV-ID genotyping and sequencing analysis for human papillomavirus (HPV) on 249 specimens. Results: EASYPREP and SurePath showed even distribution of cells and were equal in cellularity and staining quality. The diagnostic agreement between the two methods was 96.5%. Based on the standard of SurePath, the sensitivity, specificity, positive predictive value, and negative predictive value of EASYPREP were 90.7%, 99.2%, 94.8%, and 98.5%, respectively. The positivity of REBA HPV-ID was 49.4% and 95.1% in normal and abnormal cytological samples, respectively. The result of REBA HPV-ID had high concordance with sequencing analysis. Conclusions: EASYPREP provided comparable results to SurePath in the diagnosis and staining quality of cytology examinations and in HPV testing with REBA HPV-ID. EASYPREP could be another LBC method choice for the cervicovaginal specimens. Additionally, REBA HPV-ID may be a useful method for HPV genotyping.

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기사명 저자명 페이지 원문 목차
Current concepts and occurrence of epithelial odontogenic tumors. 1, Ameloblastoma and adenomatoid odontogenic tumor Suk Keun Lee, Yeon Sook Kim pp.191-202

Histopathologic predictors of lymph node metastasis and prognosis in tonsillar squamous cell carcinoma Dong Jin Lee, Mi Jung Kwon, Eun Sook Nam, Ji Hyun Kwon, Jin Hwan Kim, Young-Soo Rho, Hyung Sik Shin, Seong Jin Cho pp.203-210

Naked cuticle drosophila 1 expression in histologic subtypes of small adenocarcinoma of the lung Sangjeong Ahn, Won Hwangbo, Hyunchul Kim, Chul Hwan Kim pp.211-218

Prognostic significance of heat shock protein 70 expression in early gastric carcinoma Youngran Kang, Woon Yong Jung, Hyunjoo Lee, Wonkyung Jung, Eunjung Lee, Bong Kyung Shin, Aeree Kim, Han Kyeom Kim, Baek-hui Kim pp.219-226

Proposal for a standardized pathology report of gastroenteropancreatic neuroendocrine tumors : prognostic significance of pathological parameters Gastrointestinal Pathology Study Group of Korean Society of Pathologists, Mee-Yon Cho, Jin Hee Sohn, So Young Jin, Hyunki Kim, Eun Sun Jung, Mi-Jung Kim, Kyoung-Mee Kim, Woo Ho Kim, Joon Mee Kim … [et al.] pp.227-237

In-house manual construction of high-density and high-quality tissue microarrays by using homemade recipient agarose-paraffin blocks Kyu Ho Kim, Suk Jin Choi, Yeon Il Choi, Lucia Kim, In Suh Park, Jee Young Han, Joon Mee Kim, Young Chae Chu pp.238-244

Early colorectal epithelial neoplasm in Korea : a multicenter survey of pathologic diagnosis Gastrointestinal Pathology Study Group of Korean Society of Pathologists, Yun Kyung Kang, So-Young Jin, Mee Soo Chang, Jung Yeon Kim, Gyeong Hoon Kang, Hye Seung Lee, Jin Hee Sohn, Ho Sung Park, Kye Won Kwon … [et al.] pp.245-251

Cytologic features of ALK-positive pulmonary adenocarcinoma Seung Yeon Ha, Jungsuk Ahn, Mee Sook Roh, Joungho Han, Jae Jun Lee, Boin Lee, Jun Yim pp.252-257

Aspiration cytopathology of peripancreatic space : a clinicoradiologic and cytopathologic analyses of 42 cases Justin Bishop, Wei Zhang, Olga B. Ioffe, Syed Z. Ali pp.258-264

Cytological evaluation and REBA HPV-ID HPV testing of newly developed liquid-based cytology, EASYPREP : comparison with SurePath Youn Soo Lee, Gyungyub Gong, Jin Hee Sohn, Ki Sung Ryu, Jung Hun Lee, Shin Kwang Khang, Kyung-Ja Cho, Yong-Man Kim, Chang Suk Kang pp.265-274

Multicystic biliary hamartoma of the liver Ji Soo Song, Sang Jae Noh, Baik Hwan Cho, Woo Sung Moon pp.275-278

Heterotopic intestinal cyst of the submandibular gland : a case study Mi Jung Kwon, Dong Hoon Kim, Hye-Rim Park, Soo Kee Min, Jinwon Seo, Eun Soo Kim, Si Whan Kim, Bumjung Park pp.279-283

Myxoid liposarcoma with cartilaginous differentiation : a case study with cytogenetical analysis Hyunchul Kim, Won Hwangbo, Sangjeong Ahn, Suhjin Kim, Insun Kim, Chul Hwan Kim pp.284-288

Colonic adenocarcinoma arising from gastric heterotopia : a case study Hyoungsuk Ko, Shin Young Park, Eun Jung Cha, Jang Sihn Sohn pp.289-292

A case of multifocal papillary thyroid carcinoma consisting of one encapsulated follicular variant with BRAF K601E mutation and three conventional types with BRAF V600E mutation Wook Youn Kim, Young Sin Ko, Tae Sook Hwang, Hye Seung Han, So Dug Lim, Wan Seop Kim, Seo Young Oh pp.293-298

Imprint cytology of soft tissue myoepithelioma : a case study Seok Ju Park, Ae Ri Kim, Mi Jin Gu, Joon Hyuk Choi, Duk Seop Shin pp.299-303

Ovarian Remnant Syndrome at the Trochar Site : A Report of a Rare Complication Following Laparoscopic Ovarian Surgery 나기영, 성지윤, 원규연, 김교영, 임성직, 이석환 pp.304-306

참고문헌 (16건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 National Cancer Statistics, Seoul, Korea [Internet]. Goyang: National Cancer Information Center, 2012 [cited Jun 1]. Available from: http://www.cancer.go.kr/ncic/. 미소장
2 Liquid‐based cytology improves productivity in cervical cytology screening 네이버 미소장
3 Liquid-based cytology versus conventional Papanicolaou smear in an organized screening program : a prospective randomized study. 네이버 미소장
4 Improvement of diagnostic accuracy and screening conditions with liquid‐based cytology 네이버 미소장
5 A randomized, controlled trial of financial incentives for smoking cessation. 네이버 미소장
6 Immunocytochemistry in liquid-based cervical cytology: analysis of clinical use following a cross-sectional study. 네이버 미소장
7 The evaluation of human papillomavirus genotyping in cervical liquid-based cytology specimens; using the Roche Linear Array HPV genotyping assay. 네이버 미소장
8 Comparison of performance of conventional and ThinPrep gynecologic preparations in the College of American Pathologists Gynecologic Cytology Program. 네이버 미소장
9 Comparison of the Surepath™ liquid‐based Papanicolaou smear with the conventional Papanicolaou smear in a multisite direct‐to‐vial study 네이버 미소장
10 Gynecologic cytology on conventional and liquid‐based preparations: A comprehensive review of similarities and differences 네이버 미소장
11 Effect of Cellularity on the Sensitivity of Detecting Squamous Lesions in Liquid-Based Cervical Cytology 네이버 미소장
12 Cervical cytologic smears in pap solution vs ThinPrep : smear characteristics and diagnostic agreement 소장
13 Liquid Compared With Conventional Cervical Cytology: A Systematic Review and Meta-analysis 네이버 미소장
14 A randomized, controlled trial of financial incentives for smoking cessation. 네이버 미소장
15 Liquid‐based cytology can improve efficiency of cervical smear readers: evidence from timing surveys in two NHS cytology laboratories 네이버 미소장
16 REBA HPV‐ID® for efficient genotyping of human papillomavirus in clinical samples from Korean patients 네이버 미소장

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