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한국학술지인용색인(NRF)
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Phyllostachys pubescens (Maengjong-Juk), a kind of the bamboo, was reported to have many beneficial pharmacological actions. In this study, of using 70% ethanol extract of Phyllostachys pubescens we investigated its efficacy on angiotensin converting enzyme (ACE) and antioxidant enzyme activities. In addition, vasorelaxant effect was examined in rat aortic rings. The inhibitory effect of ACE activity by Phyllostachys pubescens extract (PPE) was dose-dependently increased by 61.42% at 10㎎/㎖. PPE relaxed the pre-contracted rat aortic rings with 10⁻⁶M phenylephrine, showing about 88% at 4.0㎎/㎖. Sprague Dawley (SD) rats were given different concentrations of PPE mixed in the drinking water for 10 weeks. PPE did not show any difference with control group in blood pressure, body weight (BW) and food intake. However, it revealed the highest total antioxidative effect at dose of 1.0 g/100 g BW in plasma by TEAC assay. Thiobarbituric acid reactive substance (TBARS) and protein carbonyl levels which are markers of tissue peroxidation, were significantly lowed at the same dosage. Furthermore, hepatic antioxidant enzymes such as total superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and catalase activities were also significantly increased by PPE (1.0 g/100 g BW). In conclusion, we suggest that PPE might have antihypertensive effect through increasing antioxidant activities.
권호기사
참고문헌 (41건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Brewster, U.C., Setaro, J.F., Perazella, M.A. The renin- angiotensin-aldosterone system; cardiorenal effects and implications for renal and cardiovascular disease states: Am. J. Med. Sci., 326: 15-24, 2003 | 미소장 |
| 2 | Anti-hypertensive Effects of Pini Folium and Leonuri Herba Extract on Spontaneously Hypertensive Rat (SHR) | 소장 |
| 3 | Antioxidative Effects of Korean Bamboo Trees, Wang-dae, Som-dae, Maengjong-juk, Jolit-dae and O-juk | 소장 |
| 4 | Bradford, M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72: 248-254, 1976 | 미소장 |
| 5 | Soffer, R.L. Angiotensin-converting enzyme and the regulation of vasoactive peptides. Annu. Rev. Biochem. 45: 73-94, 1976 | 미소장 |
| 6 | Ohara, T., Ohinata, H., Muramatsu, N. Enzymatic degradation of rutin in processing of buckwheat noodles. Nippon Shokuhin Kogyo Gakkashi 36: 121, 1989 | 미소장 |
| 7 | 김현수, 인영민, 정석근, 함준상. 자연발증고혈압쥐에서 카제인 가수분해물의 혈압강하효과. 동물자원지 44: 483-490, 2002 | 미소장 |
| 8 | Physiological and Antibacterial Activity of Bamboo(Sasa coreana Nakai) Leaves | 소장 |
| 9 | Elena, M.V., Barbara, P., Cesar, G.F. Concerted action of the renin-angiotensin system, mitochondria, and antioxidant defenses in aging. Molecular Aspects of Medicine 25: 27-36, 2004 | 미소장 |
| 10 | Chemical Properties of Hot Water Extracts from Bamboos(Phyllostuhys sp.) | 소장 |
| 11 | Antimutagenic Effects of Korean Bamboo Trees and Inhibitory Effect of Hepatic Toxicity of Bamboo Extracts Coated Rice | 소장 |
| 12 | Oxidative Stress in Arterial Hypertension  |
미소장 |
| 13 | 이영노. 한국식물도감(FLORA of Korea). 교학사, pp 970-971, 2002 | 미소장 |
| 14 | Oliver, C.N., Ahn, B., Moerman, E.J., Goldstein, S., Stadtman, E.R.. Age-related changes in oxidized proteins. J. Biol. Chem. 262: 5483-5492, 1987 | 미소장 |
| 15 | Effect of Maengjong-Juk (Phyllostachys Pubescens) Extract Coated Rice Diet on Antioxidative System of C57BL/6 Mice Fed Atherogenic Diet | 소장 |
| 16 | Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. |
미소장 |
| 17 | Food Nutrients Dictionary. J. Korean Soc. Food Sci. Nutr., p 821, 1998 | 미소장 |
| 18 | Re, R., Pellegrini, N., Proteggente, A., Pannala, A., Yang, M., Rice-Evans, C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free radical biology & Medicine 26: 1231-1237, 1999 | 미소장 |
| 19 | Yannik, M., Robert, B. Repression of gene expession by oxidative stress. Biochem. J. 342: 481-496, 1999 | 미소장 |
| 20 | Free radicals as mediators of tissue injury and disease. |
미소장 |
| 21 | Inger, C., Bengt, M. Methods in enzymology. Academic press. Inc. 113: 484-490, 1985 | 미소장 |
| 22 | Catalase in vitro. |
미소장 |
| 23 | Lee, S.K. Antimicrobial Activity of Bamboo (Phyllostachys bambusoides) Essential Oil. J. Fd Hyg. Safety.15(1):55-59, 2000 | 미소장 |
| 24 | Effect of Maengjong - Juk Extract Coated Rice Supplementation on Antioxidative System in Rabbit Fed High Cholesterol Diet | 소장 |
| 25 | Stewart, J.M., Ferreira, S.H., Greene, L.J. Bradykinin potentiating peptide PCA-Lys-Trp-Ala-Pro. An inhibitor of the pulmonary inactivation of bradykinin and conversion of angiotensin I to II. Biochem. Pharmacol. 20(7):15557-15567, 1971 | 미소장 |
| 26 | Cushman, D.W., Cheung, H.S. Spectrophotometric assay and properties of angiotensin converting enzyme of rabbit lung. Biochem. Pharm. 20: 1637-1647, 1971 | 미소장 |
| 27 | The Effect of Pear Pectin on Blood Pressure, Plasma Renin, ANP and Cardiac Hypertrophy in Hypertensive Rat Induced by 2K1C | 소장 |
| 28 | Hara, Y., Matsuzaki, T., Suzuki, T. Angiotensin I converting enzyme inhibiting activity of tea components. Nippon Shokuhin Kogyo Gakkashi, 61: 803-808, 1987 | 미소장 |
| 29 | 백종원. 국내산 대나무의 항균활성과 식품보존효과. 이학석사학위논문, 2003 | 미소장 |
| 30 | Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide |
미소장 |
| 31 | Lawrence, R.A., Burk, F. Glutathione peroxidase activity in selenium-deficient rat liver. Biochem. Biophys. Res. Commun. 71: 952-958, 1976 | 미소장 |
| 32 | Interactions between NO and reactive oxygen species: pathophysiological importance in atherosclerosis, hypertension, diabetes and heart failure. |
미소장 |
| 33 | Vascular Superoxide Production by NAD(P)H Oxidase : Association With Endothelial Dysfunction and Clinical Risk Factors |
미소장 |
| 34 | Neuroinflammatory processes are important in neurodegenerative diseases: an hypothesis to explain the increased formation of reactive oxygen and nitrogen species as major factors involved in neurodegenerative disease development |
미소장 |
| 35 | Angiotensin II induces vascular cell adhesion molecule-1 expression in rat vasculature: A potential link between the renin-angiotensin system and atherosclerosis. |
미소장 |
| 36 | 홍남두, 김종우, 최승기, 김남재, 손정곤. 죽력의 약리작용에 관한 연구 (제1보). 경희약대논문집, 10: 69-75, 1982 | 미소장 |
| 37 | Ohkawa, H., Ohishi, N., Yagi, K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95: 351, 1979 | 미소장 |
| 38 | 김영국. 식이에 의한 간지질 및 효소 활성 변화에 관한 연구. 한국영양학회지 6(1):15-29, 1973 | 미소장 |
| 39 | Samy, I.M., Ashok, K., James, R.S. Mechanisms by Which Angiotensin-Converting Enzyme Inhibitors Prevent Diabetes and Cardiovascular Disease, Am. J. Cardiol., 91: 30H-37H, 2003 | 미소장 |
| 40 | ACE Inhibitory and Antihypertensive Effect of Chitosan Oligosaccharides in SHR |
미소장 |
| 41 | Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. |
미소장 |
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