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The antioxidative activity and prevention effect from gastric cancer of Korean folk plants (KFPs) were investigated. The radical scavenging activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radical (ㆍOH) were measured. Among 52 KFPs, 21 and 52 plants at 100μg/ml showed over 80% scavenging activity of DPPH and ㆍOH, respectively. In particular, Mukdenia rossi (Oliver) Koidzumi showed the strongest radical scavenging activity against DPPH and ㆍOH. In addition, microbial inhibition activity against Helicobacter pylori (H. pylori) and growth inhibitory effects in human gastric adenocarcinoma cells (AGS) were investigated. The treatment of MeOH extracts from 9 plants at the concentration of 10μg/30μl showed strong antimicrobial activity (clear zone >13 mm) against H. pylori and 8 plants inhibited over 60% growth of AGS cells at 100μg/ml. Especially, Hemistepta lyrata Bunge and Aster incisus Fisch scavenged radical and inhibited growth of gastric cancer cells the most effectively, suggesting the promising novel resources for the prevention of degenerative diseases including gastric cancer.

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참고문헌 (28건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
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17 Helicobacter pylori Infection in Pediatrics 네이버 미소장
18 Helicobacter pylori eradication for the gastric cancer prevention 소장
19 Euphorbiae Immifusae Sensitizes Apoptosis of TRAIL-resistant Human Gastric Adenocarcinoma AGS Cells 소장
20 Helicobacter pylori and Gastric Carcinogenesis 소장
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22 Induction of gastric epithelial apoptosis by Helicobacter pylori. 네이버 미소장
23 Anti-oxidant Property and Tyrosinase Inhibition Activity of Various Extracts from plants in Compositae plants 소장
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28 Studies on the Constituents from the Flowers of Hemisteptia lyrata (Bunge) (I) 소장