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Aim of this study was to determine the effect of hydrocolloid membrane containing Styela clava tunic (HCM-SCT) on acute wound of skin. To achieve this, HCM-SCT was developed using the mixture dispersed SCT powder in hydrocolloid (HC), and an alteration on the histology and physiology of wound skin were observed in SD rats after the treatment of HCM-SCT for 11 days. Absorptiveness of HCM-SCT was rapidly increased by 430% at day 1 and then their level was maintained for a period of 4 days, while the surface roughness was higher in HCM-SCT than that of HCM.In animals study, SD rats treated with HCM-SCT did not induce any specific toxicity on the body weight, and the physical function of liver and kidney. The diameter of wound area was shorter in HCM-SCT treated group than these in Gauze (GZ) or HCM treated group. Especially, the group treated with HCM-SCT showed a significantly faster re-epithelization and decrease of epidermis thickness than those treated with HCM alone although a large amount of HC was remained in dermis region of both rats. Furthermore, the level of collagen and tumor growth factor-β1 (TGF-β1) were greatly increased in HCM-SCT treated group, while the level of angiogenesis-related proteins were significantly recovered to normal level in the same group. Therefore, these results indicate that HCM-SCT having high absorptiveness and tensile strength could accelerate the repair process of acute wound in SD rats through the stimulation of re-epithelization, collagen deposition and angiogenesis.

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참고문헌 (26건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Crystal Structure and Hydrogen-Bonding System in Cellulose Iβ from Synchrotron X-ray and Neutron Fiber Diffraction 네이버 미소장
2 Semimicro determination of cellulose inbiological materials 네이버 미소장
3 M. S. Kim and S. M. Kang, “The effect analysis on middle-aged women’s facial wrinkles improvement of shaking neck exercise and collagen,” Diet. J. Kor. Soc. Cosm., 18(6), 1223-1234 (2012). 미소장
4 Development of a bioactive cellulose membrane from sea squirt skin for bone regeneration - a preliminary research 소장
5 Chondroitin sulfate extracted from the Styela clava tunic suppresses TNF-α-induced expression of inflammatory factors, VCAM-1 and iNOS by blocking Akt/NF-κB signal in JB6 cells 네이버 미소장
6 Properties of Regenerated Cellulose Films Prepared from the Tunicate Styela clava 소장
7 Y. J. Jung, B. J. An, D. Y. Hwang, H. D. Kim, S. M. Park, H. Cho and H. S. Kim, “Preparation and properties of regenerated cellulosic biomaterial made from Styela clava tunics,” J. Biomed. Mater. Res., 12(2), 71-76 (2008). 미소장
8 Preparation and Quality Analysis of Fish Paste Containing Styela clava Tunic 소장
9 Wound coverage using advanced technology in Korea 소장
10 A comparative investigation of re-epithelialisation of split skin graft donor areas after application of hydrocolloid and alginate dressings 네이버 미소장
11 Evaluation of three new hydrocolloid dressings: retention of dressing integrity and biodegradability of absorbent components attenuate inflammation. 네이버 미소장
12 Preparation and Swelling Properties of Poly(potassium acrylate-co-acrylamide) Superabsorbent Particles 소장
13 Alginate based bilayer hydrocolloid films as potential slow-release modern wound dressing 네이버 미소장
14 Biocompatibility and growth of human keratinocytes and fibroblasts on biosynthesized cellulose-chitosan film. 네이버 미소장
15 The human type I collagen mutation database. 네이버 미소장
16 S. W. Lee, J. T. Oh, S. L. Shon and Y. S. Kim, “Monitoring of wound healing using polarization sensitive optical coherence tomography,” J. Opt. Soc. Korea, 2, 17-18 (2005) 미소장
17 Matrix Metalloproteinases (MMPs) and Their Physiological Inhibitors (TIMPs) Are Differentially Expressed during Excisional Skin Wound Repair 네이버 미소장
18 Effects of TGF-βs on the growth, collagen synthesis and collagen lattice contraction of human dental pulp fibroblasts in vitro 네이버 미소장
19 Immunopathology of human inflammatory bowel disease 네이버 미소장
20 A. Pivarcsi, I. Nagy, and L. Kemeny, “Innate immunity in the skin: how keratinocytes fight against pathogens,” Curr. Immunol. Rev., 1, 24-42 (2005). 미소장
21 R. Jayakumar, M. Prabaharan, P. T. Sudheesh Kumar, S. V. Nair, and H. Tamura, “Biomaterials based on chitin and chitosan in wound dressing applications,” Biotechnol. Adv., 29, 322-337 (2011). 미소장
22 Pulmonary fibrosis: pathogenesis, etiology and regulation. 네이버 미소장
23 Effect of oxidized regenerated cellulose/collagen matrix on dermal and epidermal healing and growth factors in an acute wound 네이버 미소장
24 The role of vascular endothelial growth factor in wound healing. 네이버 미소장
25 The Role of Vascular Endothelial Growth Factor in Wound Healing 네이버 미소장
26 NF-κB: linking inflammation and immunity to cancer development and progression 네이버 미소장

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