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Background: Scaffolds are one of the three most important elements constituting the basic concept of regenerative medicine, and are included in the core technology of regenerative medicine along with stem cells and tissue engineering. Stem cells are very important technology because they are directly responsible for the regenerative treatment of the disease and the damaged tissue, but with regards to the technology and the products that use stem cells exclusively, there is a technical limitation of limited survival rate and the engraftment rate of the transplanted cell, and rather than recovering the damaged tissue fundamentally, there is a limit that the concept is more of just another medicine treatment using cells. A scaffold is a natural or synthetic biocompatible material transplanted into a human body to be used as the exclusive treatment or as an assisted method of another treatment of a disease and for the recovery of damaged tissue. Therefore, according to the characteristics of the tissue to be applied, scaffolds must have the characteristics such as the excellent biocompatibility, biodegradability, minimum immunity and inflammation, proper mechanical strength and interaction between the material and the cells. Results: The world stem cell market was approximately 2.715 billion dollars in 2010, and with a growth rate of 16.8% annually, a market of 6.877 billion dollars will be formed in 2016. From 2017, the expected annual growth rate is 10.6%, which would expand the market to 11.38 billion dollars by 2021. Meanwhile, the world scaffold element technology market was approximately 4.57 million dollars in 2013, and by increasing 13.4% annually, it is estimated to expand to 10.63 million dollars by 2020. The Korean scaffold element technology market was about 22 million dollars in 2013, and with a steady growth of approximately 13.4% every year, it is prospected to be about 52 million dollars by 2020. Conclusions: In comparison to the medical material and medicine sales growth rate, the future scaffold element technology market is judged to be higher in growth possibility.
권호기사
참고문헌 (27건) : 자료제공( 네이버학술정보 )
| 번호 | 참고문헌 | 국회도서관 소장유무 |
|---|---|---|
| 1 | Visiongain: Stem Cell Technologies World Market Outlook 2011–2021. ; 2010. | 미소장 |
| 2 | Mano JF, Sousa RA, Boesel LF, Neves NM, Reis RL: Bioinert, biodegradable and injectable polymeric matrix composites for hard tissue replacement:state of the art and recent developments. Composites Sci Technol 2004, 64(6):789–817. | 미소장 |
| 3 | Biomimetic materials for tissue engineering  |
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| 4 | Engineering organs |
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| 5 | Regenerative Medicine and Tissue Engineering in Urology |
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| 6 | Atala A: Tissue engineering of reproductive tissues and organs. Fertil Steril 2012, 98(1):21–29. | 미소장 |
| 7 | Engineering Complex Tissues |
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| 8 | Current Status and Prospect of Biomaterials as Tissue Substitutes in Regenerative Medicine | 소장 |
| 9 | Acellular collagen matrix as a possible “off the shelf” biomaterial for urethral repair |
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| 10 | Identification and characterization of bioactive factors in bladder submucosa matrix |
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| 11 | Bladder augmentation using allogenic bladder submucosa seeded with cells |
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| 12 | A collagen matrix derived from bladder can be used to engineer smooth muscle tissue |
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| 13 | Korea Food and Drug Administration: A Study on Evaluation Criteria for Quality of Mesenchymal Stem Cell based Tissue Engineering Products:Searching for Molecular Biological Method. ; 2007. | 미소장 |
| 14 | Lee H, Khang G, Kim M, Rhee JM, Lee I, Min B: Scaffold for tissue engineering. Tissue Eng Regen Med 2006, 3(4):1738–2696. | 미소장 |
| 15 | LG Economic Research Institute: StemCell: Gap between Possibility and Reality. 2013. | 미소장 |
| 16 | Ehwa Womans University: Research on the Evaluation Method for Bioactive Medical Devices. ; 2009. | 미소장 |
| 17 | Current Status and Future Perspectives of Stem Cells and Regenerative Medicine | 소장 |
| 18 | TriMark Publication: Regenerative Medicine Markets. ; 2013. | 미소장 |
| 19 | Biomedical applications of collagen |
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| 20 | Job L, van Susante C, Jeroen P, Pieter B, van Kuppevelt TH, van Beuningen H, van der Kraan PM, Veerkamp JH, van den Berg WB, René P, Veth H:Linkage of chondroitin-sulfate to type I collagen scaffolds stimulates the bioactivity of seeded chondrocytes in vitro Biomaterials. Biomaterials 2001, 22(17):2359–2369. | 미소장 |
| 21 | The effect of selected growth factors on human anterior cruciate ligament cell interactions with a three‐dimensional collagen‐GAG scaffold |
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| 22 | Recent Applications of Polymeric Biomaterials and Stem Cells in Tissue Engineering and Regenerative Medicine | 소장 |
| 23 | Shinhan Investment Corp: Sector Report: Stem-Cell Theraphy Products. 2011. | 미소장 |
| 24 | 10 Growth Strategies for Stem Cell Industry. Korea Health Industry Development Institute; 2005. | 미소장 |
| 25 | Investment Strategies for Stem Cell Technology. Korean Ministry of Education, Korean Ministry of Health and Welfare, Korean Ministry of Knowledge Economy, Korean Ministry of Agriculture, Food and Rural Affairs. 2012. | 미소장 |
| 26 | HTStec: 3D Cell Culture Trends 2011. 2011. | 미소장 |
| 27 | Korea Health Industry Development Institute: Medical Resource Statistics Handbook. 2012. | 미소장 |
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