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The objective of this study was to determine the anti-atherosclerotic effects of pine nut oil in rats fed a high-cholesterol and high-fat diet (HCHF). Using a randomized block design, Sprague-Dawley rats were divided into 5 groups and fed experimental diets for 6 weeks (normal diet, HCHF, HCHF+7 or 15% pine nut oil, HCHF+simvastatin). This study shows that markers of atherosclerosis, such as increased liver thiobarbituric acid reactive substance levels, aortic fatty streak area, and low-density lipoprotein cholesterol concentrations, were lower in the HCHF plus pine nut oil groups than in the HCHF group. Conversely, positive cardiovascular indicators, such as increased paraoxonase activity and high-density lipoprotein cholesterol concentrations, were higher in HCHF plus pine nut oil groups than in the HCHF group. This study suggests that pine nut oil improves atherosclerotic markers and could be used as a functional ingredient in the food industry to promote cardiovascular health.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
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Anti-atherosclerosis Effect of Pine Nut Oil in High-cholesterol and High-fat Diet Fed Rats and Its Mechanism Studies in Human Umbilical Vein Endothelial Cells 강윤환, 김경곤, 김태우, 최면 pp.323-332
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Antioxidant Activity of Water Extracts of Persimmon Flower Buds 윤운영, 최소연, 김시경, 김진우, 곽연식, 이승철 pp.281-286
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Quality Evaluation of Fresh Tomato Juices Prepared Using High-speed Centrifugal and Low-speed Masticating Household Juicers 김민주, 김정인, 강민정, 권보경, 전정규, 최지혜, Myo-Jeong Kim pp.61-66
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Comparison of Soy Protein Concentrates Produced Using Membrane Ultrafiltration and Acid Precipitation 김현정, 김병기 pp.67-73
Microbial Inhibition in Mozzarella Cheese Using Rosemary and Thyme Oils in Combination with Sodium Diacetate 한정훈, Dhaval Patel, 김정은, 민세철 pp.75-84
A Functional Egg Yolk Powder Containing an Antibody against Niemann-Pick C1-Like1(NPC1L1) Lowers Cholesterol Levels in High Cholesterol Diet Induced Hypercholesterolemic SD Rats 김대환, 최미란, 홍지은, 이재용, 권혁세, 장상호, Eun Ji Kim pp.217-223
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참고문헌 (32건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Anderson TJ. Arterial stiffness or endothelial dysfunction as a surrogate marker of vascular risk. Can. J. Cardiol. 22 (Suppl. B):72B-80B (2006) 미소장
2 Atherosclerosis: humoral and cellular factors of inflammation 네이버 미소장
3 Badimon L, Vilahur G. LDL-cholesterol versus HDL-cholesterol in the atherosclerotic plaque: Inflammatory resolution versus thrombotic chaos. Ann. NY Acad. Sci. 1254: 18-32 (2012) 미소장
4 Atheroprotective effect of oleoylethanolamide (OEA) targeting oxidized LDL. 네이버 미소장
5 Singh V, Sharma R, Kumar A, Deedwania P. Low high-density lipoprotein cholesterol: Current status and future strategies for management. Vasc. Health Risk Manag. 6: 979-996 (2010) 미소장
6 Aortic antioxidant defence mechanisms: time-related changes in cholesterol-fed rabbits 네이버 미소장
7 Kim JK, Kim SH, Noh KH, Jang JH, Song YS. Effects of green tea seed oil on the cholesterol, TBARS, and inflammatory responses in C57BL/6 mice fed high cholesterol diet. J. Korean Soc. Food Sci. Nutr. 36: 284-290 (2007) 미소장
8 Dietary Therapy for Prevention of Atherosclerosis 소장
9 Lee SH, Jang MS. Physicochemical properties of jatjook as influenced by various levels of pinenut. Korean J. Soc. Food Sci. 10: 99-103 (1994) 미소장
10 Park YS, Chung MS. Cholesterol-lowering effect of pine nut in plasma of rats. Korean J. Food Sci. Technol. 37: 702-708 (2005) 미소장
11 Yoon TH, Lee SM. Effect on blood lipids and lipoproteins of a supplement of Korean pinenut oil, rich in 5-Olefinic acids, in normocholesterolemic New Zealand white rabbits. Korean J. Nutr. 27: 323-335 (1994) 미소장
12 Aceampong A, Leveque N, Tchapla A, Heron S. Simple complementary liquid chromatography and mass spectrometry approaches for the characterization of triacylglycerols in Pinus koraiensis seed oil. J. Chromatogr. A 1218: 5087-5100 (2011) 미소장
13 Kamal-Eldin A, Mreau RA. Tree nut oils. pp. 127-149. In: Gourmet and Health Promoting Specialty Oils. Moreau RA, Kamal-Eldin A (eds). AOCS Press, Urbana, IL, USA (2009) 미소장
14 Impact of Korean pine nut oil on weight gain and immune responses in high-fat diet-induced obese mice. 소장
15 Lee KW, Yu KW, Kim KM, Suh HJ, Lee SW, Rhee C. Effect of pine (Pinus koraiensis)-seed oil supplementation on serum lipid composition in rats and immune response in mice. Food Sci. Biotechnol. 13: 358-361 (2004) 미소장
16 Wolff RL, Bayard CC. Fatty acid composition of some pine seed oils. J. Am. Oil. Chem. Soc. 72: 1043-1046 (1995) 미소장
17 Linoleic acid and coronary heart disease 네이버 미소장
18 Effects of oleic acid rich oils on aorta lipids and lipoprotein lipase activity of spontaneously hypertensive rats. 네이버 미소장
19 Leanness and heightened nonresting energy expenditure: role of skeletal muscle activity thermogenesis. 네이버 미소장
20 Individual differences in physical activity are closely associated with changes in body weight in adult female rhesus monkeys (Macaca mulatta). 네이버 미소장
21 Jung JH, Kim HS. The inhibitory effect of black soybean on hepatic cholesterol accumulation in high cholesterol and high fat dietinduced non-alcoholic fatty liver disease. Food Chem. Toxicol. 60:404-412 (2013) 미소장
22 Lu B, Xia D, Huang W, Wu X, Zhang Y, Yao Y. Hypolipidemic effect of bamboo shoot oil (P. pubescens) in Sprague-Dawley rats. J. Food Sci. 75: H205-H211 (2010) 미소장
23 Anti-atherosclerotic potential of gossypetin via inhibiting LDL oxidation and foam cell formation 네이버 미소장
24 Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver. 네이버 미소장
25 Lipid Peroxidation and Its Toxicological Implications 소장
26 Multiple actions of high-density lipoprotein 네이버 미소장
27 Watson AD, Berliner JA, Hama SY, La Du BN, Faull KF, Fogelman AM, Navab M. Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein. J. Clin. Invest. 96:2882-2891 (1995) 미소장
28 Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio. 네이버 미소장
29 Diet enriched with korean pine nut oil improves mitochondrial oxidative metabolism in skeletal muscle and brown adipose tissue in diet-induced obesity. 네이버 미소장
30 Selective increase in pinolenic acid (all-cis-5,9,12-18:3) in Korean pine nut oil by crystallization and its effect on LDL-receptor activity. 네이버 미소장
31 Luteolin Inhibits Angiotensin II-Induced Human Umbilical Vein Endothelial Cell Proliferation and Migration Through Downregulation of Src and Akt Phosphorylation 네이버 미소장
32 The endothelium in atherogenesis. 네이버 미소장