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Herein we investigate the influence of hydrophilic polymers on the buccal permeability of collagen hydrolysate (CGH) by performing in vitro buccal permeation test and viscosity measurements. After we demonstrated that CGH (2000-3000 Da) could be delivered across the reconstructed human buccal tissue as evaluated by hydroxyproline assay, the effects of different hydrophilic polymers, varying amounts of CGH, and hydration methods were examined to elucidate the relationship with buccal permeation behavior of CGH. The percentage of CGH permeated was found to be highest in HPMC E5 solution and greater when the viscosity of test solutions was low. Using commercially obtained CGH-loaded buccal films, the films under higher hydration condition exhibited greater CGH permeation. This study demonstrates that CGH can be delivered via the human buccal tissue and viscosity of the solution significantly affects the CGH permeation. These findings are valuable for designing hydrophilic polymer-based buccal film formulations for peptides like CGH.

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기사명 저자명 페이지 원문 목차
Droplet-based continuous flow synthesis of palladium supported on reduced graphene oxide Yea Seul Jang, Su Min Nam, Go Eun Son, Jihoon Lee, Chan Pil Park p. 374-377

Formation of cytosine and uracil from cyanoacetylaldehyde and guanidine : a computational study Joong Chul Choe p. 382-384

Diastereoselective synthesis of phosphorodiamidate morpholino dimers So Jeong Min, Na Young Kim, Hyun Young Chae, Keun Ho Chun p. 252-253

Fabrication and characterization of MWCNTs by syngas and temperature conditions Suyoung Park, Sangwoo Kim, Han Gil Na, Sun-Woo Choi, Changhyun Jin p. 279-283

Identification of the geographical origin of Asian red pepper (Capsicum annuum L.) powders using 1H NMR spectroscopy Dongwon Lee, Miso Kim, Byung Hee Kim, Sangdoo Ahn p. 317-322

Copper-promoted synthesis of β-selenylated cyclopentanones via selenylation and 1,2-alkyl migration sequences of alkenyl cyclobutanols Yubin Kim, Dae Young Kim p. 378-381

Effect of operational parameters on the degradation of methylene blue using visible light active BiVO4 photocatalyst Malathi Arumugam, Myong Yong Choi p. 304-309

Dye adsorption on plate-like nanocrystalline Bi2WO6 synthesized by microwave hydrothermal methods Young-Jin Kim, Chunghee Nam p. 332-335

An invariable temperature during the phase transition of W doped VO2 film Seong-Cheol Hong, Myeongsoon Lee, Don Kim p. 323-331

Colorimetric probe coupled to dispersive liquid-liquid microextraction for determination of dopamine in serum Zhi-gang Tai, Yi-ren Zhu, Yi-bo Yuan, Jin Liu, Zhen-jie Li, Zhi-hua Liu, Kun-miao Wang p. 284-289

Viscosity effects of hydrophilic polymers on transport of collagen hydrolysate across reconstructed human buccal tissue Jain Koo, Seohyun Lee, Sooho Yeo, Dohyun Kim, Minwoo Park, Tack Soo Nam, Jaehwi Lee p. 290-295

Electrodeposition of zinc oxide nanowires as a counter electrode in electrochromic devices Hong Chul Lim, Eunji Park, Ik-Soo Shin, Jong-In Hong p. 358-361

High-performance microbial fuel cell using metal ion complexes as electron acceptors Guorong Xie, Chansoo Choi p. 348-357

Identification of a novel oxadiazole inhibitor of mammalian target of rapamycin Sunwoo Lim, Hyomin Lee, Euijung Kim, Wooyoung Hur p. 296-303

The structural effect of benzoate surfactant tails on the activity of lipoprotein lipase in organic solvent Yeonock Oh p. 366-369

Simultaneous determination of hydroquinone and catechol by N-doped porous biochar-modified electrode Yue-Xin Liu, Shi-Man Du, Jie Cao, Wen-sheng Huang, Xiao-Ru Zhang, Bao-Ping Qi, Sheng-Hui Zhang p. 261-265

Amyloid fibril formation of α-synuclein is modulated via the estrogen receptor ligand binding domain of estrogen receptor α bound with tamoxifen-based small molecules Dawon Lee, Soyoung Yoon, Jinwoo Lee, Dongyeol Lim, Chun Yoon, Hana Im, Kyunghee Lee p. 274-278

Transition metal-free phosphorylation of vinyl azides : a convenient synthesis of β-ketophosphine oxides Jihoon Jang, Dae Young Kim p. 370-373

Obscurin and clusterin elevation in serum of acute myocardial infarction patients Min-Jung Kang, Yunseo Seong, Joyeta Mahmud, Binh Thanh Nguyen p. 266-273

Synthesis of porous carbon-coated cobalt catalyst through pyrolyzing metal-organic framework and their bifunctional OER/ORR catalytic activity for Zn-air rechargeable batteries Yunseung Kuk, Sheraz Ahmed, Ho-Jung Sun, Joongpyo Shim, Gyungse Park p. 310-316

Calculating hermitian forms : the importance of considering singular points Somnath Bhowmick, Denis Hagebaum-Reignier, Gwang-Hi Jeung p. 254-260

A study on transparent electrode properties of indium tin oxide thin films deposited from recycled target Ki-Seong Lee, Yeong Jun Mo, Ik Keun Park, Tae-Sung Park, Young Sung Kim p. 341-347

Tranexamic acid analysis as ethoxycarbonyl-tert-butyldimethylsilyl derivatives by gas chromatography-tandem mass spectrometry Hyung-Jin Park, Hyeon-Seong Lee, Chan Seo, Jeuk Min, Moongi Ji, Youngbae Kim, Subin Choi, Doo-Young Kim, Jung Dong Kim, Do Hyeon Jeong, Wonjae Lee, Man-Jeong Paik p. 336-340

Diffusion and kinetic-controlled electrochemical reactions for improving the performance of solution-based electrochemiluminescence devices Hong Chul Lim, Ji-Eun Park, Jong-In Hong, Ik-Soo Shin p. 362-365

참고문헌 (26건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
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