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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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Objectives. This study was conducted to compare clinicopathologic and radiologic factors between benign and malignant thyroid nodules and to evaluate the diagnostic performance of shear wave elastography (SWE) combined with B-mode ultrasonography (US) in differentiating malignant from benign thyroid nodules.

Methods. This retrospective study included 92 consecutive patients with 95 thyroid nodules examined on B-mode US and SWE before US-guided fine-needle aspiration biopsy or surgical excision. B-mode US findings (composition, echogenicity, margin, shape, and calcification) and SWE elasticity parameters (maximum [Emax], mean, minimum, and nodule-to-normal parenchymal ratio of elasticity) were reviewed and compared between benign and malignant thyroid nodules. The diagnostic performance of B-mode US and SWE for predicting malignant thyroid nodules was analyzed. The optimal cutoff values of elasticity parameters for identifying malignancy were determined. Diagnostic performance was compared between B-mode US only, SWE only, and the combination of B-mode US with SWE.

Results. On multivariate logistic regression analysis, age (odds ratio [OR], 0.90; P=0.028), a taller-than-wide shape (OR, 11.3; P=0.040), the presence of calcifications (OR, 15.0; P=0.021), and Emax (OR, 1.22; P=0.021) were independent predictors of malignancy in thyroid nodules. The combined use of B-mode US findings and SWE yielded improvements in sensitivity, the positive predictive value, the negative predictive value, and accuracy compared with the use of B-mode US findings only, but with no statistical significance.

Conclusion. When SWE was combined with B-mode US, the diagnostic performance was better than when only B-mode US was used, although the difference was not statistically significant.

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참고문헌 (28건) : 자료제공( 네이버학술정보 )

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번호 참고문헌 국회도서관 소장유무
1 New sonographic criteria for recommending fine-needle aspiration biopsy of nonpalpable solid nodules of the thyroid. 네이버 미소장
2 Ha EJ, Moon WJ, Na DG, Lee YH, Choi N, Kim SJ, et al. A multicenter prospective validation study for the Korean thyroid imaging reporting and data system in patients with thyroid nodules. Korean J Radiol. 2016 Sep-Oct;17(5):811-21. 미소장
3 US Features of thyroid malignancy: pearls and pitfalls. 네이버 미소장
4 Risk for malignancy of thyroid nodules as assessed by sonographic criteria: the need for biopsy. 네이버 미소장
5 Approach to the patient with a cytologically indeterminate thyroid nodule. 네이버 미소장
6 Thyroid Fine-Needle Aspiration Biopsy: Progress, Practice, and Pitfalls 네이버 미소장
7 WFUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography: Part 4. Thyroid 네이버 미소장
8 Elastography: A quantitative method for imaging the elasticity of biological tissues 네이버 미소장
9 Nell S, Kist JW, Debray TP, de Keizer B, van Oostenbrugge TJ, Borel Rinkes IH, et al. Qualitative elastography can replace thyroid nodule fine-needle aspiration in patients with soft thyroid nodules: a systematic review and meta-analysis. Eur J Radiol. 2015 Apr;84(4): 652-61. 미소장
10 US-elastography in the differential diagnosis of benign and malignant thyroid nodules. 네이버 미소장
11 Monpeyssen H, Tramalloni J, Poiree S, Helenon O, Correas JM. Elastography of the thyroid. Diagn Interv Imaging. 2013 May;94(5):535-44. 미소장
12 Quantitative Assessment of Breast Lesion Viscoelasticity: Initial Clinical Results Using Supersonic Shear Imaging 네이버 미소장
13 Breast lesions: quantitative elastography with supersonic shear imaging--preliminary results. 네이버 미소장
14 Shear wave elastography versus real-time elastography on evaluation thyroid nodules: A preliminary study 네이버 미소장
15 Prospective evaluation of multiparametric ultrasound and quantitative elastosonography in the differential diagnosis of benign and malignant thyroid nodules: Preliminary experience 네이버 미소장
16 Comparison analysis between conventional ultrasonography and ultrasound elastography of thyroid nodules 네이버 미소장
17 Elastography in Distinguishing Benign from Malignant Thyroid Nodules. 네이버 미소장
18 Shear wave elastography of thyroid nodules for the prediction of malignancy in a large scale study 네이버 미소장
19 Veyrieres JB, Albarel F, Lombard JV, Berbis J, Sebag F, Oliver C, et al. A threshold value in Shear Wave elastography to rule out malignant thyroid nodules: a reality? Eur J Radiol. 2012 Dec;81(12):3965-72. 미소장
20 Shear wave elastography and contrast-enhanced ultrasonography in the diagnosis of thyroid malignant nodules. 네이버 미소장
21 Shear wave elastography combined with the thyroid imaging reporting and data system for malignancy risk stratification in thyroid nodules. 네이버 미소장
22 Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016 Jan;26(1):1-133. 미소장
23 Azizi G, Keller JM, Mayo ML, Piper K, Puett D, Earp KM, et al. Thyroid nodules and shear wave elastography: a new tool in thyroid cancer detection. Ultrasound Med Biol. 2015 Nov;41(11):2855-65. 미소장
24 Thyroid imaging reporting and data system for US features of nodules: a step in establishing better stratification of cancer risk. 네이버 미소장
25 Thyroid Imaging Reporting and Data System Risk Stratification of Thyroid Nodules: Categorization Based on Solidity and Echogenicity 네이버 미소장
26 Shin JH, Baek JH, Chung J, Ha EJ, Kim JH, Lee YH, et al. Ultrasonography diagnosis and imaging-based management of thyroid nodules: revised Korean Society of Thyroid Radiology consensus statement and recommendations. Korean J Radiol. 2016 May-Jun;17(3): 370-95. 미소장
27 The diagnostic performance of shear wave speed (SWS) imaging for thyroid nodules with elasticity modulus and SWS measurement. 네이버 미소장
28 Shear wave elastography of thyroid nodules in routine clinical practice: preliminary observations and utility for detecting malignancy 네이버 미소장

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