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Apathy is a highly prevalent, disabling and treatment resistant syndrome. It is defined as a quantitative reduction of goal-directed activity in comparison to the patient’s previous level of in multiple dimensions including behavior/cognition, emotion and social interaction. It has been described in major depressive disorder, Alzheimer’s disease, frontotemporal dementia, Parkinson’s Disease, cerebrovascular disease, and vascular dementia, among others. This review will address the neuropsychology and associated neurobiological underpinnings of apathy in the above conditions, identify specific methods to assess apathy clinically, and review the literature on managing apathy across these various disorders.

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기사명 저자명 페이지 원문 목차
Apathy : neurobiology, assessment and treatment Mario Fahed, David C. Steffens p. 181-189

(An) overview of deep learning algorithms and their applications in neuropsychiatry Gokhan Guney, Busra Ozgode Yigin, Necdet Guven, Yasemin Hosgoren Alici, Burcin Colak, Gamze Erzin, Gorkem Saygili p. 206-219

Methyl jasmonate : behavioral and molecular implications in neurological disorders Oritoke Modupe Aluko, Joy Dubem Iroegbu, Omamuyovwi Meashack Ijomone, Solomon Umukoro p. 220-232

Clinical benefit and utility of switching to aripiprazole once monthly in patients with antipsychotic polypharmacy or long acting injectable antipsychotics for patients with schizophrenia in routine practice : a retrospective, observation study Chi-Un Pae, Changsu Han, Won-Myong Bahk, Soo-Jung Lee, Ashwin A. Patkar, Prakash S. Masand p. 233-242

Additional reduction of residual symptoms with aripiprazole augmentation in the patients with partially remitted major depressive disorder Cheolmin Shin, Chi-Un Pae, Kyung Phil Kwak, Sang Won Jeon, Hyun-Ghang Jeong, Jong-Woo Kim, Youn Jung Lee, Ashwin A. Patkar, Changsu Han p. 243-253

Does the loudness dependence of auditory evoked potential predict response to selective serotonin reuptake inhibitors? : a meta-analysis Sunkyung Yoon, Yourim Kim, Seung-Hwan Lee p. 254-261

MiR-132 and miR-942 expression levels in children with attention deficit and hyperactivity disorder : a controlled study Seyma Coskun, Mehmet Karadag, Cem Gokcen, Serdar Oztuzcu p. 262-268

Are mannan-binding lectine serin protease-2 and alpha-1-microglobulin and bukinin precursor the potential biomarkers of manic episode? A study via urinary proetomic analysis Cem Cerit, Mehmet Sarıhan, Ömer Nart, Murat Kasap, Hilmi Yaşar, Gürler Akpınar p. 269-281

Effectiveness of N-acetylcysteine in treating clinical symptoms of substance abuse and dependence : a meta-analysis of randomized controlled trials Chung-Ting Chang, Pei-Ju Hsieh, Hsin-Chien Lee, Chun-Hong Lo, Ka-Wai Tam, El-Wui Loh p. 282-293

Pre-transplant dementia is associated with poor survival after hematopoietic stem cell transplantation : a nationwide cohort study with propensity score matched control Sheng-Min Wang, Sung-Soo Park, See Hyun Park, Nak-Young Kim, Dong Woo Kang, Hae-Ran Na, Young-Yi Bae, Jong Wook Lee, Seunghoon Han, Hyun Kook Lim p. 294-302

Prediction of locomotor activity by infrared motion detector on sleep-wake state in mice Jeonghyun Park, Min Soo Jung, Eun Soo Moon, Hyun Ju Lim, Chi Eun Oh, Jung Hyun Lee p. 303-312

Quantitative resting state electroencephalography in patients with schizophrenia spectrum disorders treated with strict monotherapy using atypical antipsychotics Takashi Ozaki, Atsuhito Toyomaki, Naoki Hashimoto, Ichiro Kusumi p. 313-322

Relationship between the loudness dependence of the auditory evoked potential and the severity of suicidal ideation in patients with major depressive disorder Mingyu Hwang, Yeon Jung Lee, Minji Lee, Byungjoo Kang, Yun Sung Lee, Jaeuk Hwang, Sung-il Woo, Sang-Woo Hahn p. 323-333

(The) relationship between plasma erythropoietin levels and symptoms of attention deficit hyperactivity disorder Se-Hoon Shim, Yong-Ku Kim, Young Hwangbo, Hee-jung Yoon, Ji Sun Kim, Youn Jung Lee, Young Sup Woo, Won-Myong Bahk p. 334-340

Rapid onset of intranasal esketamine in patients with treatment resistant depression and major depression with suicide ideation : a meta-analysis Sheng-Min Wang, Nak-Young Kim, Hae-Ran Na, Hyun Kook Lim, Young Sup Woo, Chi-Un Pae, Won-Myong Bahk p. 341-354

Effect of varenicline on tardive dyskinesia : a pilot study Stanley N. Caroff, Alisa R. Gutman, John Northrop, Shirley H. Leong, Rosalind M. Berkowitz, E. Cabrina Campbell p. 355-360

Body mass index and somatic symptom severity in patients with somatic symptom disorder : the mediating role of working memory Hee Jin Kim, Hye Ri Kim, Jae-Chan Jin, Doug Hyun Han, Sun Mi Kim p. 361-366

'Z-trip'? A comprehensive overview and a case-series of zolpidem misuse Laura Orsolini, Stefania Chiappini, Paolo Grandinetti, Angelo Bruschi, Roberta Testa, Alessandra Provenzano, Domenico De Berardis, Umberto Volpe p. 367-387

Psychoses of epilepsy in pregnancy : a case report Mario Fahed, Seethalakshmi Ramanathan p. 388-390

Personalization of repetitive transcranial magnetic stimulation for the treatment of major depressive disorder according to the existing psychiatric comorbidity Po-Han Chou, Yen-Feng Lin, Ming-Kuei Lu, Hsin-An Chang, Che-Sheng Chu, Wei Hung Chang, Taishiro Kishimoto, Alexander T. Sack, Kuan-Pin Su p. 190-205

참고문헌 (56건) : 자료제공( 네이버학술정보 )

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번호 참고문헌 국회도서관 소장유무
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37 Liu J, Cooper CA, Weintraub D, Dahodwala N. Pharmacological treatment of apathy in Lewy body disorders: a systematic review. Parkinsonism Relat Disord 2019;60:14-24. 미소장
38 Pagonabarraga J, Kulisevsky J, Strafella AP, Krack P. Apathy in Parkinson’s disease: clinical features, neural substrates, diagnosis, and treatment. Lancet Neurol 2015;14:518-531. 미소장
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40 Sockeel P, Dujardin K, Devos D, Denève C, Destée A, Defebvre L. The Lille apathy rating scale (LARS), a new instrument for detecting and quantifying apathy: validation in Parkinson’s disease. J Neurol Neurosurg Psychiatry 2006;77:579-584. 미소장
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