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미성숙 감(Diospyros kaki Thunb. Sangju-Dungsi) 에탄올 추출물의 항알레르기 생리활성 연구 ＝ Study on the anti-allergic effect using immature persimmon(Diospyros kaki thunb. Sangju-Dungsi) ethanol extract / 이명진 ; 김배환 1

Abstract 1

재료 및 방법 2

연구 결과 5

고찰 8

결론 12

인용문헌 12

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This study was conducted to verify the availability of immature persimmon ethanol extract (IPEE) as a natural and functional ingredient in protecting inflammation and allergy of skin based on the mechanism. The major content analysis, antioxidant activities, anti-allergic activity, anti-inflammatory effect, and safety related to irritation of IPEE were evaluated. The gallic acid content per 10 mg/mL of IPEE was 0.522% (5.22 mg/g). The total polyphenol and flavonoid contents were 428.3 mg/g and 31.1 mg/g, respectively. In ABTS+ activity, DPPH ability and SOD-like activity, it showed a concentration-dependent increase, which indicated IPEE has excellent antioxidant activities. As for the anti-allergy test in RBL-2H3 cells, the IPEE showed a decrease in β-hexosaminidase secretion as the concentration increases, and IPEE tended to decrease IL-4 secretion in all RBL-2H3 cells compared to the IgE + HSA group. IPEE showed good anti-inflammatory effect in RAW 264.7 cells by decrease of NO production and inflammation cytokines (TNF-α and IL-6). Also IPEE showed non-irritant in BCOP assay. By the results of this study, the IPEE containing high tannins, had good antioxidant, anti-allergic, and anti-inflammatory effects, which indicated that the immature persimmon is considered to be a useful for the development of related functional ingredients.

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기사명 저자명 페이지 원문 목차
금은화에서 분리한 luteolin의 신경세포보호 활성 = Neuroprotective activity of luteolin isolated from Lonicera japonica 김은서, 마충제 p. 1-7

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아까시나무 뿌리껍질의 항염증활성물질 = Anti-inflammatory constituents of Robinia pseudoacacia root bark 강동민, 박우성, 김혜진, 정우진, 강권규, 안미정 p. 8-15

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금불초 지상부의 Diterpene 배당체 성분 = Diterpene glycosides from the aerial parts of Inula britannica var. chinensis regel 김대근, 김준형 p. 16-20

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자궁경부암 줄기세포에 대한 꽃송이버섯 메탄올 추출물의 클로로포름 분획의 항암 활성 = Anticancer activity of chloroform fraction of methanol extract of Sparassis crispa in human cervical cancer stem cells 한장미, 김성민, 김혜영, 백승배, 정혜진 p. 21-28

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미성숙 감(Diospyros kaki Thunb. Sangju-Dungsi) 에탄올 추출물의 항알레르기 생리활성 연구 = Study on the anti-allergic effect using immature persimmon(Diospyros kaki thunb. Sangju-Dungsi) ethanol extract 이명진, 김배환 p. 29-41

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극지해면동물 Sphaerotylus antarcticus 추출물의 RANKL 유도 파골세포 분화 및 ROS 생성 억제 효과 = Inhibitory effect of RANKL-induced osteoclast differentiation and ROS generation by Sphaerotylus antarcticus extract 김은남, 강다연, 응웬민짱, 이준혁, 고영욱, 김상희, 나민균, 정길생 p. 42-48

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감태나무 에틸아세테이트 분획의 항염증 및 진통 효과 = Anti-inflammatory and anti-nociceptive effects of ethyl acetate fraction of Lindera glauca 김종수, 강보혜, 박승주, 양우인, 김명수, 이병수, 차동석, 이세연, 권진, 전훈 p. 49-56

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참고문헌 (50건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
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