본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

초록보기

Pyroptosis, apoptosis, necroptosis, and ferroptosis, which are the most well-studied regulated cell death (RCD) pathways, contribute to the clearance of infected or potentially neoplastic cells, highlighting their importance in homeostasis, host defense against pathogens, cancer, and a wide range of other pathologies. Although these four RCD pathways employ distinct molecular and cellular processes, emerging genetic and biochemical studies have suggested remarkable flexibility and crosstalk among them. The crosstalk among pyroptosis, apoptosis and necroptosis pathways is more evident in cellular responses to infection, which has led to the conceptualization of PANoptosis. In this review, we provide a brief overview of the molecular mechanisms of pyroptosis, apoptosis, necroptosis, and ferroptosis and their importance in maintaining homeostasis. We discuss the intricate crosstalk among these RCD pathways and the current evidence supporting PANoptosis, focusing on infectious diseases and cancer. Understanding the fundamental processes of various cell death pathways is crucial to inform the development of new therapeutics against many diseases, including infection, sterile inflammation, and cancer.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
AIVariant : a deep learning-based somatic variant detector for highly contaminated tumor samples Hyeonseong Jeon, Junhak Ahn, Byunggook Na, Soona Hong, Lee Sael, Sun Kim, Sungroh Yoon, Daehyun Baek p. 1-9

Dysregulation of the Wnt/β-catenin signaling pathway via Rnf146 upregulation in a VPA-induced mouse model of autism spectrum disorder Gaeun Park, Wooyoung Eric Jang, Seoyeon Kim, Edson Luck Gonzales, Jungeun Ji, Seunghwan Choi, Yujin Kim, Ji Hwan Park, Hazara Begum Mohammad, Geul Bang ... [et al.] p. 1-12

SLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAPK/ERK and PI3K/AKT pathways Xiaojuan Ren, Chao Feng, Yubo Wang, Pu Chen, Simeng Wang, Jianling Wang, Hongxin Cao, Yujun Li, Meiju Ji, Peng Hou p. 1-13

Reversing pancreatic β-cell dedifferentiation in the treatment of type 2 diabetes Jinsook Son, Domenico Accili p. 1-7

Phosphoinositides and intracellular calcium signaling : novel insights into phosphoinositides and calcium coupling as negative regulators of cellular signaling Byung-Chul Oh p. 1-11

Olfactory modulation of stress-response neural circuits Min-Gi Shin, Yiseul Bae, Ramsha Afzal, Kunio Kondoh, Eun Jeong Lee p. 1-13

Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair Eunhwan Kim, Seol Hwa Seo, Yumi Hwang, Yeong Chan Ryu, Heejene Kim, Kyoung-Mi Lee, Jin Woo Lee, Kwang Hwan Park, Kang-Yell Choi p. 1-13

Thrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy Hyun-Jun Jang, Yo Han Lee, Tam Dao, Yunju Jo, Keon Woo Khim, Hye-jin Eom, Ju Eun Lee, Yi Jin Song, Sun Sil Choi, Kieun Park ... [et al.] p. 1-14

ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression Guiwen Ye, Jinteng Li, Wenhui Yu, Zhongyu Xie, Guan Zheng, Wenjie Liu, Shan Wang, Qian Cao, Jiajie Lin, Zepeng Su ... [et al.] p. 1-14

Establishment of a humanized mouse model of keloid diseases following the migration of patient immune cells to the lesion : patient-derived keloid xenograft (PDKX) model A Ram Lee, Seon-Yeong Lee, Jeong Won Choi, In Gyu Um, Hyun Sik Na, Jung Ho Lee, Mi-La Cho p. 1-7

Impact of the circadian nuclear receptor REV-ERBα in dorsal raphe 5-HT neurons on social interaction behavior, especially social preference Sangwon Jang, Inah Park, Mijung Choi, Jihoon Kim, Seungeun Yeo, Sung-Oh Huh, Ji-Woong Choi, Cheil Moon, Han Kyoung Choe, Youngshik Choe, Kyungjin Kim p. 1-14

Microbiota influences host exercise capacity via modulation of skeletal muscle glucose metabolism in mice Hye Jin Kim, Youn Ju Kim, Yong Jae Kim, Ji Hyeon Baek, Hak Su Kim, Il Yong Kim, Je Kyung Seong p. 1-11

(A) single-cell atlas of in vitro multiculture systems uncovers the in vivo lineage trajectory and cell state in the human lung Woochan Lee, Seyoon Lee, Jung-Ki Yoon, Dakyung Lee, Yuri Kim, Yeon Bi Han, Rokhyun Kim, Sungji Moon, Young Jun Park, Kyunghyuk Park ... [et al.] p. 1831-1842

(An) integrated view of lipid metabolism in ferroptosis revisited via lipidomic analysis Jong Woo Kim, Ji-Yoon Lee, Mihee Oh, Eun-Woo Lee p. 1620-1631

Mitochondria-associated programmed cell death as a therapeutic target for age-related disease Thanh T. Nguyen, Shibo Wei, Thu Ha Nguyen, Yunju Jo, Yan Zhang, Wonyoung Park, Karim Gariani, Chang-Myung Oh, Hyeon Ho Kim, Ki-Tae Ha ... [et al.] p. 1595-1619

Regulated cell death pathways and their roles in homeostasis, infection, inflammation, and tumorigenesis Ein Lee, Chang-Hyun Song, Sung-Jin Bae, Ki-Tae Ha, Rajendra Karki p. 1632-1643

Diversity and complexity of cell death : a historical review Wonyoung Park, Shibo Wei, Bo-Sung Kim, Bosung Kim, Sung-Jin Bae, Young Chan Chae, Dongryeol Ryu, Ki-Tae Ha p. 1573-1594

After cell death : the molecular machinery of efferocytosis Byeongjin Moon, Susumin Yang, Hyunji Moon, Juyeon Lee, Daeho Park p. 1644-1651

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기