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Nanomaterials such as hydroxyapatite have been extensively researched, thanks to their unsual properties, which are similar in chemical composition to bone tissue. In addition, hydroxyapatite nanoparticles offer a wide range of possibilities for functionalization which make it an interesting material for target drug delivery applications, showing strong potential for coupling natural substances such as curcumin to improve the antitumor effect of this substance in the fight against cancer. Curcumin has been researched over the years, thanks to its anticancer properties. Hydroxyapatite also allows the incorporation of paramagnetic elements into their structure, such as gadolinium (Gd), allowing the production of a probe for diagnostic imaging using nuclear magnetic resonance imaging systems. In this work, hydroxyapatite nanorods (HA) doped with Gd were synthesized to produce folic acid (FA) functionalized nanostructures for targeted delivery of curcumin (CM). The samples were characterized using various techniques, including Fourier transform infrared spectroscopy (FTIR), UV-visible spectroscopy (UV-Vis), X-ray diffraction (XRD), thermogravimetric analysis (TGA), zeta potential analysis (ζ), transmission electron microscopy (TEM), and vibrating samples magnetometry (VSM). The results indicated a successful obtaining of paramagnetic HA-Gd nanostructures functionalized with FA and CM, exhibiting characteristics that credit this system for future biological assays in order to evaluate their efficiency in the treatment and diagnosis of osteosarcoma

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권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Simulation testing of performance of cement-based high ductility nano-earthquake resistant materials and its application in housing structure Sicong Du, Zhenhua Fu, Hongyan Gu p. 921-925

Analysis of the surface characteristics of SiO2-Al2O3-CaO-ZnO-Na2O-based glass at heat-treatment temperature using Raman spectroscopy Dongchan Kim, Seunggu Kang p. 926-934

Forming a thick CdZnTe epitaxial film by sublimating closely spaced Xiang-Xiang Luo, Cheng-Fang Qiao, Simon R Hall, Chun-Sheng Zhou p. 935-940

Electrocaloric properties of BaTiO3/La0.7Sr0.3MnO3/BaTiO3 multilayer thin films prepared by chemical solution deposition Jae-Uk Lee, Jeong-Eun Lim, Ji-Soo Yuk, Sam-Haeng Yi, Myung-Gyu Lee, Joo-Seok Park, Young-Gon Kim, Sung-Gap Lee p. 941-946

Microstructure and wear behavior of WC-30WB-10Co cemented carbide coating sprayed by HVOF Baogang Liu, Sam Lu, Haifan Zhu p. 947-953

Investigation of the structural and optical properties of sol gel processed Ho-doped BaTiO3 ceramics Adil Moutaouaffiq, Ali Didi Seddik, Abdelilah Rjeb, Mohammed Naciri Bennani, Mohamed Naji, Salaheddine Sayouri p. 954-962

Synthesis of Ca14Zn6Al10O35:Mn4+, Nd3+ phosphor using starch as an impregnation medium Soo-Jong Kim p. 963-967

(The) influence of process parameters on the optical properties of seashell-added ceramic glazes, evaluated using a factorial design Ceren Peksen p. 968-976

Microwave dielectric properties of Li3Mg2SbO5F2 oxyfluorides ceramics produced by reaction-sintering method Pengshen Wu, Cuijin Pei, Miao Chen, Xu Gao, Weihong Liu, Guoguang Yao, Jin Liu p. 977-982

(A) dual-functional gadolinium-conjugated hydroxyapatite nanoparticle-containing curcumin as a potential nanoplatform for bioapplications Jéssica Pauline Nunes Marinho, Marcelo Fernandes Cipreste, Alisson Krohling, Edésia Martins Barros Sousa p. 983-991

(A) study on microstructural and dielectric properties of Ba0.5-xZnxSr0.45Ca0.05TiO3 ceramics Ying-Chieh Lee, Hui-Ju Hsu, I-Yu Huang, Huei-Jyun Shih, Christian Pithan p. 992-1000

Effects of ZnO and Al2O3 on optical properties of sanitary ware glazes without ZrSiO4 Yeonju Kim, Kangduk Kim, Kyu-sung Han p. 1001-1009

Crystallinity of silicon/carbon composite materials for rechargeable battery Jinsuk Lee, Yujeong Ahn, Sihyun Lee p. 1010-1024

Study on grinding mechanism and machining technology of Si3N4 ceramic spindle Songhua Li, Chuang Li, Minghe Liu, Yonghua Wang, Chuang Zuo, Hao Zhang, Yifeng Gao p. 1025-1036

Study on the influence of building materials processing technology on diversified artistic expression of architecture Zhongyu Liang, Yina Zhang, Taofeng Li p. 1037-1041

Mixed alkali effect on the thermal properties of SiO2-B2O3-ZnO-K2O-Na2O glass system Sungmin Son, Seunggu Kang p. 1042-1049

Optimization of welding parameters for better tensile strength through coupled genetic algorithm and firefly algorithm for AA7010-SiC-Al2O3 hybrid composite P. Gopi Krishnan, R. Srinivasan, D. Pritima, A. Bovas Herbert Bejaxhin p. 1050-1059

Wettability and corrosion of molten sodium carbonate on aluminum-silicon refractory Zhigang Xu, Yi Xia, Yizhao Mu p. 1060-1065

Synthesis of hydrophobically modified, rice husk-derived spherical silica particles Jin Hyung Lee, Ji Yeon Park, Jinyoung Chun, Byoung Seung Jeon, Hye Sun Lee, Byoung-In Sang p. 1066-1070

Optimization of heat transfer parameter in fractal tree microchannel with Al2O3 nano-fluids using Taguchi and GRA method E. Manikandan, K. Velmurugan, G.G. Sozhamannan, Balamuruga Mohan Raj.G, V.S.K. Venkatachalapathy p. 1071-1078