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국회도서관 홈으로 정보검색 소장정보 검색

초록보기

Objective: This study was conducted to investigate the differential expression of the major histocompatibility complex (MHC) gene region in Eimeria-infected broiler.

Methods: We profiled gene expression of Eimeria-infected and uninfected ceca of broilers sampled at 4, 7, and 21 days post-infection (dpi) using RNA sequencing. Differentially expressed genes (DEGs) between two sample groups were identified at each time point. DEGs located on chicken chromosome 16 were used for further analysis. Kyoto encyclopedia of genes and genomes (KEGG) pathway analysis was conducted for the functional annotation of DEGs.

Results: Fourteen significant (false discovery rate 〈0.1) DEGs were identified at 4 and 7 dpi and categorized into three groups: MHC-Y class I genes, MHC-B region genes, and non-MHC genes. In Eimeria-infected broilers, MHC-Y class I genes were upregulated at 4 dpi but downregulated at 7 dpi. This result implies that MHC-Y class I genes initially activated an immune response, which was then suppressed by Eimeria. Of the MHC-B region genes, the DMB1 gene was upregulated, and TAP-related genes significantly implemented antigen processing for MHC class I at 4 dpi, which was supported by KEGG pathway analysis.

Conclusion: This study is the first to investigate MHC gene responses to coccidia infection in chickens using RNA sequencing. MHC-B and MHC-Y genes showed their immune responses in reaction to Eimeria infection. These findings are valuable for understanding chicken MHC gene function.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Comparison of miR-106b, miR-191, and miR-30d expression dynamics in milk with regard to its composition in Holstein and Ayrshire cows Marina V. Pozovnikova, Viktoria B. Leibova, Olga V. Tulinova, Elena A. Romanova, Artem P. Dysin, Natalia V. Dementieva, Anastasiia I. Azovtseva, Sergey E. Sedykh p. 965-981

Multiomics analyses of Jining Grey goat and Boer goat reveal genomic regions associated with fatty acid and amino acid metabolism and muscle development Zhaohua Liu, Xiuwen Tan, Qing Jin, Wangtao Zhan, Gang Liu, Xukui Cui, Jianying Wang, Xianfeng Meng, Rongsheng Zhu, Ke Wang p. 982-992

Major histocompatibility complex genes exhibit a potential immunological role in mixed Eimeria-infected broiler cecum analyzed using RNA sequencing Minjun Kim, Thisarani Kalhari Ediriweera, Eunjin Cho, Yoonji Chung, Prabuddha Manjula, Myunghwan Yu, John Kariuki Macharia, Seonju Nam, Jun Heon Lee p. 993-1000

Effect of Codonopsis pilosula polysaccharide on the quality of sheep semen preservation at 4°C Yuqin Wang, Yanhong Zhao, Hua Chen, Tingting Lu, Rujie Yang, Xiuxiu Weng, Wanhong Li p. 1001-1006

Improving the meiotic competence of small antral follicle-derived porcine oocytes by using dibutyryl-cAMP and melatonin Jakree Jitjumnong, Pin-Chi Tang p. 1007-1020

RNA helicase DEAD-box-5 is involved in R-loop dynamics of preimplantation embryos Hyeonji Lee, Dong Wook Han, Seonho Yoo, Ohbeom Kwon, Hyeonwoo La, Chanhyeok Park, Heeji Lee, Kiye Kang, Sang Jun Uhm, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong p. 1021-1030

Impact of different levels of lactose and total solids of the liquid diet on calf performance, health, and blood metabolites Gercino Ferreira Virgínio Júnior, Cécile Anna Jeanne Duranton, Marilia Ribeiro de Paula, Carla Maris Machado Bittar p. 1031-1040

Bacillus subtilis improves antioxidant capacity and optimizes inflammatory state in broilers Yu Zhang, Junyan Zhou, Linbao Ji, Lian Zhang, Liying Zhao, Yubing Guo, Haitao Wei, Lin Lu p. 1041-1052

Interaction effects of glycine equivalent and standardized ileal digestible threonine in low protein diets for broiler grower chickens Paschal Chukwudi Aguihe, Amanda Barroso Castelani, Camilo Ivan Ospina-Rojas, Eustace Ayemere Iyayi, Paulo Cesar Pozza, Alice Eiko Murakami p. 1053-1064

Effects of dietary mulberry leaves on growth, production performance, gut microbiota, and immunological parameters in poultry and livestock : a systematic review and meta-analysis Bing Geng, Jinbo Gao, Hongbing Cheng, Guang Guo, Zhaohong Wang p. 1065-1076

Predicting standardized ileal digestibility of lysine in full-fat soybeans using chemical composition and physical characteristics Chanwit Kaewtapee, Rainer Mosenthin p. 1077-1084

Effect of extrusion on available energy and amino acid digestibility of barley, wheat, sorghum, and broken rice in growing pigs Ge Zhang, Gang Zhang, Jinbiao Zhao, Ling Liu, Zeyu Zhang p. 1085-1095

Exploration of nutritional and bioactive peptide properties in goat meat from various primal cuts during in vitro gastrointestinal digestion and absorption Pichitpon Luasiri, Papungkorn Sangsawad, Jaksuma Pongsetkul, Pramote Paengkoum, Chatsirin Nakharuthai, Saranya Suwanangul, Sasikan Katemala, Narathip Sujinda, Jukkrapong Pinyo, Jarunan Chainam, Chompoonuch Khongla, Supaluk Sorapukdee p. 1096-1109

Welfare assessment traits, milk quantity and quality, and profitability of Anatolian buffalo cows confined in closed-tied or semi-open free-stall barns can be affected by supplementary feeding at milking İbrahim Cihangir Okuyucu, Ahmet Akdağ, Hüseyin Erdem, Canan Kop-Bozbay, Samet Hasan Abacı, Ali Vaiz Garipoğlu, Esin Hazneci, Nuh Ocak p. 1110-1120

Does calf-mother contact during heat stress period affect physiology and performance in buffaloes? Nripendra Pratap Singh, Madan Lal Kamboj p. 1121-1129

Heat tolerance of goats to increased daily maximum temperature and low salinity of drinking water in tropical humid regions Asep Indra Munawar Ali, Sofia Sandi, Lili Warly, Armina Fariani, Anggriawan Naidilah Tetra Pratama, Abdullah Darussalam p. 1130-1139

참고문헌 (32건) : 자료제공( 네이버학술정보 )

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번호 참고문헌 국회도서관 소장유무
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