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Filamentous fungi are important cell factories for the production of high-value enzymes and chemicals for the food, chemical, and pharmaceutical industries. Under submerged fermentation, filamentous fungi exhibit diverse fungal morphologies that are influenced by environmental factors, which in turn affect the rheological properties and mass transfer of the fermentation system, and ultimately the synthesis of products. In this review, we first summarize the mechanisms of mycelial morphogenesis and then provide an overview of current developments in methods and strategies for morphological regulation, including physicochemical and metabolic engineering approaches. We also anticipate that rapid developments in synthetic biology and genetic manipulation tools will accelerate morphological engineering in the future.

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권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Research progress on strategies for improving the enzyme properties of bacteriophage endolysins Yulu Wang, Xue Wang, Xin Liu, Bokun Lin p. 1189-1196

Morphological engineering of filamentous fungi : research progress and perspectives Zhengwu Lu, Zhiqun Chen, Yunguo Liu, Xuexue Hua, Cuijuan Gao, Jingjing Liu p. 1197-1205

Evaluating the nutritional composition of unripe citrus and its effect on inhibiting adipogenesis and adipocyte differentiation Sunghee Kim, Eunbi Lee, Juhye Park, Ju-Ock Nam, Soo Rin Kim p. 1206-1213

(The) metabolic functional feature of gut microbiota in mongolian patients with type 2 diabetes Yanchao Liu, Hui Pang, Na Li, Yang Jiao, Zexu Zhang, Qin Zhu p. 1214-1221

(A) small epitope tagging on the C-terminus of a target protein requires extra amino acids to enhance the immune responses of the corresponding antibody Kyungha Lee, Man-Ho Cho, Mi-Ju Kim, Seong-Hee Bhoo p. 1222-1228

Preparation and performance evaluation of a zinc oxide-graphene oxideloaded chitosan-based thermosensitive gel Hao Huang, Rui Han, Ping-Ping Huang, Chuan-Yue Qiao, Shuang Bian, Han Xiao, Lei Ma p. 1229-1238

Production of exopolysaccharides and İndole acetic acid (IAA) by rhizobacteria and their potential against drought stress in upland rice Tetty Marta Linda, Jusinta Aliska, Nita Feronika, Ineiga Melisa, Erwina Juliantari p. 1239-1248

Diverse mycena fungi and their potential for gastrodia elata germination Xiao-Han Jin, Yu-Chuan Wang, Dong Li, Yu Li, Hai-Yan He, Han-Bo Zhang p. 1249-1259

Unveiling the bacterial community across the stomach, hepatopancreas, anterior intestine, and posterior intestine of pacific whiteleg shrimp Dhiraj Kumar Chaudhary, Sang-Eon Kim, Hye-Jin Park, Kyoung-Ho Kim p. 1260-1269

Flavonoids biotransformation by human gut bacterium Dorea sp. MRG-IFC3 cell-free extract Huynh Thi Ngoc Mi, Heji Kim, Jong Suk Lee, Bekir Engin Eser, Jaehong Han p. 1270-1275

Novel Qnr families as conserved and intrinsic quinolone resistance determinants in Aeromonas spp. Sang-Gyu Kim, Bo-Eun Kim, Jung Hun Lee, Dae-Wi Kim p. 1276-1286

(The) combination of Bacillus natto JLCC513 and ginseng soluble dietary fiber attenuates ulcerative colitis by modulating the LPS/TLR4/NF-κB pathway and gut microbiota Mingyue Ma, Yueqiao Li, Yuguang He, Da Li, Honghong Niu, Mubai Sun, Xinyu Miao, Ying Su, Hua Zhang, Mei Hua, Jinghui Wang p. 1287-1298

Fermented milk containing Lacticaseibacillus rhamnosus SNU50430 modulates immune responses and gut microbiota in antibiotic-treated mice Sunghyun Yoon, SungJun Park, Seong Eun Jung, Cheonghoon Lee, Woon-Ki Kim, Il-Dong Choi, GwangPyo Ko p. 1299-1306

Red pine bark extract alleviates akt/GSK-3β signaling disruption in the hippocampus of streptozotocin-induced diabetic Sprague-Dawley rats Kwan Joong Kim, Zukhra Akhmedova, Ho Jin Heo, Dae-Ok Kim p. 1307-1313

Bacterial growth modulatory effects of two branched-chain hydroxy acids and their production level by gut microbiota Chan Hyuk Hwang, Su-Hyun Kim, Choong Hwan Lee p. 1314-1321

Target recognition triggered split DNAzyme based colorimetric assay for direct and sensitive methicillin-resistance analysis of Staphylococcus aureus Jin Xu, Dandan Jin, Zhengwei Wang p. 1322-1327

Potential protective effect of selenium-enriched Lactobacillus plantarum on cadmium-induced liver injury in mice Yanyan Song, Jing Zhang, Yidan Li, Yuxuan Wang, Yingxin Wan p. 1328-1339

Anti-inflammatory effects of hydroethanolic extract from Ehretia asperula on lipopolysaccharide-stimulated RAW264.7 macrophages Bao Le, Vo Thi Kim Hong, Seung Hwan Yang p. 1340-1347

(A) novel inhibitor of translation initiation factor eIF5B in Saccharomyces cerevisiae Ah-Ra Goh, Yi-Na Kim, Jae Hyeun Oh, Sang Ki Choi p. 1348-1355

Synthesis of isoamyl fatty acid ester, a flavor compound, by immobilized Rhodococcus Cutinase Ye Won Jeon, Ha Min Song, Ka Yeong Lee, Yeong A Kim, Hyung Kwoun Kim p. 1356-1364

참고문헌 (93건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Cell Polarity in Filamentous Fungi: Shaping the Mold 미소장
2 Morphological development of Aspergillus niger in submerged citric acid fermentation as a function of the spore inoculum level. Application of neural network and cluster analysis for characterization of mycelial morphology 미소장
3 Improved lipid accumulation by morphology engineering of oleaginous fungus Mortierella isabellina 미소장
4 Morphology and productivity of filamentous fungi 미소장
5 Studying pellet formation of a filamentous fungus Rhizopus oryzae to enhance organic acid production 미소장
6 Pellet morphology, culture rheology and lovastatin production in cultures of Aspergillus terreus 미소장
7 Genomic analysis of the aconidial and high-performance protein producer, industrially relevant Aspergillus niger SH2 strain 미소장
8 Effect of volumetric power input by aeration and agitation on pellet morphology and product formation of Aspergillus niger 미소장
9 Enhanced cellulase production by Trichoderma viride in a rotating fibrous bed bioreactor 미소장
10 Scale up and design of processes in aerated-stirred fermenters for the industrial production of vinegar 미소장
11 Optimization of biomass, pellet size and polygalacturonase production by Aspergillus sojae ATCC 20235 using response surface methodology 미소장
12 Effect of pellet size and stimulating factor on the glucosamine production using Aspergillus sp. BCRC 31742 미소장
13 Metabolic Engineering of the Morphology of Aspergillus 미소장
14 Relationship between morphology and citric acid production in submerged Aspergillus niger fermentations 미소장
15 Approaches to functional genomics in filamentous fungi 미소장
16 Effect of branch frequency inAspergillus oryzae on protein secretion and culture viscosity 미소장
17 Two zinc finger transcription factors, CrzA and SltA, are involved in cation homoeostasis and detoxification in Aspergillus nidulans 미소장
18 Effects of soybean meal hydrolysate as the nitrogen source on seed culture morphology and fumaric acid production by Rhizopus oryzae 미소장
19 Change in hyphal morphology of Aspergillus oryzae during fed-batch cultivation 미소장
20 Fungal morphology and metabolite production in submerged mycelial processes 미소장
21 Taxonomy and significance of black aspergilli 미소장
22 Effect of the aeration rate and agitation speed on β-carotene production and morphology of Blakeslea trispora in a stirred tank reactor: mathematical modeling 미소장
23 Characterization and control of fungal morphology for improved production performance in biotechnology 미소장
24 Hydrodynamic and kinetic study of cellulase production by Trichoderma reesei with pellet morphology 미소장
25 Customization of <em>Aspergillus niger</em> Morphology Through Addition of Talc Micro Particles 미소장
26 Morphological changes induced by class III chitin synthase gene silencing could enhance penicillin production of Penicillium chrysogenum 미소장
27 Culture-Based Strategies for Reduction of Protease Activity in Filtrates from Aspergillus niger NRRL-3 미소장
28 Production of recombinant proteins by filamentous fungi 미소장
29 G‐protein signalling mediates differential production of toxic secondary metabolites 미소장
30 Tip Growth in Filamentous Fungi: A Road Trip to the Apex 미소장
31 The capacity of Aspergillus niger to sense and respond to cell wall stress requires at least three transcription factors: RlmA, MsnA and CrzA 미소장
32 SclR, a Basic Helix-Loop-Helix Transcription Factor, Regulates Hyphal Morphology and Promotes Sclerotial Formation in Aspergillus oryzae 미소장
33 Reconstruction of Signaling Networks Regulating Fungal Morphogenesis by Transcriptomics 미소장
34 Morphology engineering of Aspergillus niger for improved enzyme production 미소장
35 Metabolic Engineering of the Morphology of Aspergillus oryzae by Altering Chitin Synthesis 미소장
36 Genetically shaping morphology of the filamentous fungus Aspergillus glaucus for production of antitumor polyketide aspergiolide A 미소장
37 Improved enzyme production by bio-pellets of Aspergillus niger: Targeted morphology engineering using titanate microparticles 미소장
38 Regulation of Secondary Metabolism in Filamentous Fungi 미소장
39 The Morphology of Filamentous Fungi 미소장
40 Microparticle‐enhanced cultivation of filamentous microorganisms: Increased chloroperoxidase formation by Caldariomyces fumago as an example 미소장
41 Characterization and overexpression of the Aspergillus niger gene encoding the cAMP-dependent protein kinase catalytic subunit 미소장
42 Morphology engineering - Osmolality and its effect on Aspergillus niger morphology and productivity 미소장
43 Morphology and physiology of an α-amylase producing strain of Aspergillus oryzae during batch cultivations 미소장
44 The filamentous fungal pellet and forces driving its formation 미소장
45 Roles of Protein Kinase A and Adenylate Cyclase in Light-Modulated Cellulase Regulation in Trichoderma reesei 미소장
46 VelB/VeA/LaeA Complex Coordinates Light Signal with Fungal Development and Secondary Metabolism 미소장
47 Genome sequencing and analysis of the filamentous fungus Penicillium chrysogenum 미소장
48 Chemoattractive Mechanisms in Filamentous Fungi 미소장
49 Characterization of the Ca2+-responsive signaling pathway in regulating the expression and secretion of cellulases inTrichoderma reeseiRut-C30 미소장
50 Controlling filamentous fungi morphology with microparticles to enhanced β-mannanase production 미소장
51 Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper 미소장
52 Natural products from filamentous fungi and production by heterologous expression 미소장
53 Comparative genomics and transcriptome analysis of Aspergillus niger and metabolic engineering for citrate production 미소장
54 Transcriptome analysis of the two unrelated fungal β-lactam producers Acremonium chrysogenum and Penicillium chrysogenum: Velvet-regulated genes are major targets during conventional strain improvement programs 미소장
55 (Reference title not available) 미소장
56 Molecular tools for gene manipulation in filamentous fungi 미소장
57 The filamentous fungal pellet—relationship between morphology and productivity 미소장
58 Morphological regulation of Aspergillus niger to improve citric acid production by chsC gene silencing 미소장
59 Fungal Morphogenesis, from the Polarized Growth of Hyphae to Complex Reproduction and Infection Structures 미소장
60 5S rRNA Promoter for Guide RNA Expression Enabled Highly Efficient CRISPR/Cas9 Genome Editing in Aspergillus niger 미소장
61 How a fungus shapes biotechnology: 100 years of Aspergillus niger research 미소장
62 A Consensus Ochratoxin A Biosynthetic Pathway: Insights from the Genome Sequence of Aspergillus ochraceus and a Comparative Genomic Analysis 미소장
63 Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast 미소장
64 Creating a functional single-chromosome yeast 미소장
65 Rocking Aspergillus: morphology-controlled cultivation of Aspergillus niger in a wave-mixed bioreactor for the production of secondary metabolites 미소장
66 Enhancement of Monascus pigment productivity via a simultaneous fermentation process and separation system using immobilized-cell fermentation 미소장
67 Engineering of filamentous fungi for efficient conversion of lignocellulose: Tools, recent advances and prospects 미소장
68 Induction of pigment production through media composition, abiotic and biotic factors in two filamentous fungi 미소장
69 Filamentous fungi for the production of enzymes, chemicals and materials 미소장
70 Moulding the mould: understanding and reprogramming filamentous fungal growth and morphogenesis for next generation cell factories 미소장
71 New insights on yeast and filamentous fungus adhesion in a natural co-immobilization system: proposed advances and applications in wine industry 미소장
72 Filamentous fungi in biological control: current status and future perspectives 미소장
73 Morphology engineering of Aspergillus oryzae for l‐malate production 미소장
74 A quantitative image analysis pipeline for the characterization of filamentous fungal morphologies as a tool to uncover targets for morphology engineering: a case study using aplD in Aspergillus niger 미소장
75 Members of chitin synthase family in Metarhizium acridum differentially affect fungal growth, stress tolerances, cell wall integrity and virulence 미소장
76 Status of filamentous fungi in integrated biorefineries 미소장
77 Sustainable and Effective Chitosan Production by Dimorphic Fungus Mucor rouxii via Replacing Yeast Extract with Fungal Extract 미소장
78 Control of Actin and Calcium for Chitin Synthase Delivery to the Hyphal Tip of Aspergillus 미소장
79 Monitoring of Aspergillus terreus morphology for the lovastatin production in submerge culture by impedimetry 미소장
80 Fungi as a Potential Source of Pigments: Harnessing Filamentous Fungi 미소장
81 The mechanisms of hyphal pellet formation mediated by polysaccharides, α-1,3-glucan and galactosaminogalactan, in Aspergillus species 미소장
82 Regulating Strategies for Producing Carbohydrate Active Enzymes by Filamentous Fungal Cell Factories 미소장
83 Clustering analysis of large-scale phenotypic data in the model filamentous fungus Neurospora crassa 미소장
84 Disruption of the Trichoderma reesei gul1 gene stimulates hyphal branching and reduces broth viscosity in cellulase production 미소장
85 Applications of CRISPR/Cas9 in the Synthesis of Secondary Metabolites in Filamentous Fungi 미소장
86 Orchestration an extracellular lipase production from Aspergillus niger MYA 135: biomass morphology and fungal physiology 미소장
87 Modular Synthetic Biology Toolkit for Filamentous Fungi 미소장
88 Customization of <em>Aspergillus niger</em> Morphology Through Addition of Talc Micro Particles 미소장
89 Cell Biology of Hyphal Growth 미소장
90 Studying Pellet Formation of a Filamentous Fungus Rhizopus oryzae to Enhance Organic Acid Production 미소장
91 Bioreactors and engineering of filamentous fungi cultivation 미소장
92 Recent Advances in Chitin Biosynthesis Associated with the Morphology and Secondary Metabolite Synthesis of Filamentous Fungi in Submerged Fermentation 미소장
93 Engineering the metabolism and morphology of the filamentous fungus Trichoderma reesei for efficient L-malic acid production 미소장

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