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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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국회도서관 홈으로 정보검색 소장정보 검색
결과 내 검색 동의어 포함
결과 내 검색 동의어 포함

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Background: Dengue virus (DENV) is transmitted by mosquitoes and is becoming a global threat owing to an increase in the number of cases and mortality, especially in low- and middle-income tropical countries. Rapid and easy-to-use diagnostic tests are required to differentiate dengue fever from other febrile illnesses.

Methods: We evaluated the clinical performance of the ImmuneMed Dengue NS1 Ag Rapid I test (ImmuneMed, Inc.) using positive and negative sera collected from patients with confirmed DENV infection and healthy individuals, respectively. The AccuPower® ZIKV (DENV, CHIKV) multiplex real-time reverse transcription polymerase chain reaction (RT-PCR) assay (Bioneer) was used as the reference standard to confirm DENV infection.

Results: One hundred DENV-positive and 161 DENV-negative samples were evaluated. Overall, the sensitivity and specificity were 100% (95% confidence interval [CI], 96%–100%) and 100% (95% CI, 98%–100%), respectively. The sensitivity and specificity were 100% for both DENV-1 and DENV- 2. The sensitivity was the same (100%) for sera collected ＜ 3 days and ≥ 3 days from symptom onset. The performance of the ImmuneMed Dengue NS1 Ag Rapid I and real-time RT-PCR tests showed strong overall agreement.

Conclusion: The ImmuneMed Dengue NS1 Ag Rapid I test was highly specific for DENV and as sensitive as RT-PCR. These findings suggest that the ImmuneMed Dengue NS1 Ag Rapid I test may be a useful point-of-care test for dengue fever.

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기사명 저자명 페이지 원문 목차
Malaria diagnostics : from traditional techniques to cutting-edge solutions Jin-Hee Han, Eun-Taek Han p. 155-170

Roles of clinical microbiology in hospital environmental cleaning and disinfection : a narrative review Young Ah Kim p. 171-177

Essential data for developing bacteriophage therapeutics Dongeun Yong p. 179-183

Seasonality and epidemiological trends in species distribution and antifungal susceptibility of Candida species isolated from various clinical specimens conducted during 2011–2022, Korea : a retrospective surveillance study Seo Young Hwang, Young Kwan Lim, Kye Won Choe, Young ho Choi, Mi-Kyung Lee p. 185-196

Clinical performance of the ImmuneMed Dengue NS1 Ag Rapid I test for the diagnosis of dengue fever : a diagnostic accuracy study Teddy Namirimu, Sunjoo Kim p. 197-204

Verification of the Mycoplasma IST3 for urogenital mycoplasma culture in comparison to the Mycoplasma IST2 Seungtaek Lim, Seunghwan Seol, Eun Jeong Won, Bosung Park, Heungsup Sung, Mi-Na Kim p. 205-214

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