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Adhesion to the human gut epithelium is essential for the beneficial effects of probiotics.

A human organoid-derived intestinal epithelial cell (IEC) monolayer model recapitulateskey features of the gut epithelium and overcomes limitations of three-dimensionalcultures, providing a suitable platform for assessing bacterial adhesion. In this study, weevaluated the adhesion capacity of the probiotic strain Lactobacillus gasseri BNR17 to humanIECs using fluorescence-based analysis and colony-forming unit assays. BNR17 retainedhigh fluorescence intensity after washing and exhibited approximately 20-fold greaterviable adhesion than the control strain Limosilactobacillus fermentum ACE21. These resultsdemonstrate the strong adhesive capacity of L. gasseri BNR17, supporting its potential foreffective gut colonization and health promotion.

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권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Lactobacillus gasseri BNR17 exhibits superior adhesion in a human intestinal organoid-derived model Yu Mi Jo, Chang Won Ahn, Ji-Hyun Yun p. 1-10
Effects of the Weissella cibaria CXO-1 postbiotic and its mixture with peppermint oil powder on halitosis-causing bacteria Jungeun Kim, Yun-Ju Cho, Ji Hwan Jang p. 1-9
Antioxidant effects of Porphyra tenera extract on H2O2-induced oxidative stress in human epidermal keratinocytes Subin Park, Junho Yu, Miey Park, Hae-Jeung Lee p. 1-9
Effects of milk thistle intake on consumers’ health status Inbae Ji p. 1-10
Ginseng berry concentrate promotes a metabolic shift from anaerobic glycolysis to aerobic mitochondrial metabolism in C2C12 myocytes Su Hwan Kim, Hyun Woo Jeong, Jonghee Sohn, Byung-Fhy Suh, Chan Woong Park p. 1-12