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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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In this study, we evaluated the inhibitory activity of the postbiotic derived from Weissella cibaria CXO-1, obtained by heat treatment, against the halitosis-causing strains Fusobacterium nucleatum KCTC 2640 and Porphyromonas gingivalis KCTC 5352, and assessed its antibacterial synergy when combined with peppermint oil powder, a widely used oral-malodor control agent. The postbiotic showed the minimum inhibitory concentration (MIC) values of 9.4 mg/mL against F. nucleatum KCTC 2640 and 37.5 mg/mL against P. gingivalis KCTC 5352, and began to inhibit the production of hydrogen sulfide/methyl mercaptan from 4.7/9.4 mg/mL, and 37.5/37.5 mg/mL, respectively, demonstrating intrinsic antibacterial action. Peppermint oil powder alone also exhibited antibacterial activity, with MICs of 12.5 mg/mL against F. nucleatum KCTC 2640 and 1.6 mg/mL against P. gingivalis KCTC 5352. When combined, MIC was substantially lowered: the postbiotic decreased to 1.2 mg/mL against F. nucleatum KCTC 2640 and 4.7 mg/mL against P. gingivalis KCTC 5352, while peppermint oil powder decreased to 6.3 mg/mL and 0.8 mg/mL, respectively, indicating 2- to 8-fold enhanced potency. Collectively, these data confirm that the W. cibaria CXO-1 postbiotic has an antibacterial efficacy, that is further amplified by co-formulation with peppermint oil powder, supporting its potential as a novel functional oral-care ingredient for halitosis management.

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기사명 저자명 페이지 원문 목차
Lactobacillus gasseri BNR17 exhibits superior adhesion in a human intestinal organoid-derived model Yu Mi Jo, Chang Won Ahn, Ji-Hyun Yun p. 1-10
Effects of the Weissella cibaria CXO-1 postbiotic and its mixture with peppermint oil powder on halitosis-causing bacteria Jungeun Kim, Yun-Ju Cho, Ji Hwan Jang p. 1-9
Antioxidant effects of Porphyra tenera extract on H2O2-induced oxidative stress in human epidermal keratinocytes Subin Park, Junho Yu, Miey Park, Hae-Jeung Lee p. 1-9
Effects of milk thistle intake on consumers’ health status Inbae Ji p. 1-10
Ginseng berry concentrate promotes a metabolic shift from anaerobic glycolysis to aerobic mitochondrial metabolism in C2C12 myocytes Su Hwan Kim, Hyun Woo Jeong, Jonghee Sohn, Byung-Fhy Suh, Chan Woong Park p. 1-12

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