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Hypogonadism in men with a history of prostate cancer presents a complex clinical challenge, with longstanding concerns that testosterone replacement therapy (TRT) could potentially stimulate cancer recurrence or progression. This paper provides an up-to-date review of the evidence on the safety and efficacy of TRT, focusing on its use in key clinical scenarios such as active surveillance, post-radical prostatectomy, and post-radiotherapy. We examine the latest data on oncological safety, including risks of disease progression and biochemical recurrence, alongside the benefits of TRT in addressing hypogonadal symptoms such as fatigue, mood disturbance, and sexual dysfunction. The discussion also considers how TRT safety aligns with advancements in prostate cancer biology, including the saturation model, and how these insights are reflected in guidelines from major organisations such as the British Society for Sexual Medicine (BSSM), American Urological Association (AUA), and European Association of Urology (EAU). Gaps in long-term data and areas for further research are identified, underscoring the need for careful application in clinical practice. This paper emphasises a multidisciplinary approach in patient selection, rigorous monitoring protocols, and fully informed decision-making. By presenting a comprehensive review of the evidence, we aim to clarify the role of TRT in improving quality of life for men in remission from prostate cancer, while ensuring that oncological safety remains the highest priority.

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권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Testosterone replacement therapy in hypogonadal men with a prostate cancer diagnosis : a British Society for Sexual Medicine consensus statement Marie Alexandra Edison, Michael Kirby, Geoffrey Ian Hackett p. 5-22
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Nocturia, sleep quality, and mortality : a systematic review and meta-analysis Alvin Christopher Lavadia, Jae Heon Kim, Seong Woo Yun, Tae Il Noh p. 36-48
Efficacy and tolerability outcomes of minimally invasive surgical treatments for benign prostatic hyperplasia : a random-effects network meta-analysis Brian Ng Hung Shin, Rebekah Maksoud, Samuel Tan, Handoo Rhee, Hyun Jun Park, Eric Chung p. 49-63
Global Andrology Forum (GAF) clinical guidelines on the management of infertile men with varicocele Selahittin Çayan, Germar-M. Pinggera, Widi Atmoko, Taha Hamoda, Rupin Shah, Armand Zini, Eric Chung, Giovanni Maria Colpi, Amarnath Rambhatla, Hiva Alipour ... [et al.] p. 64-77
Global andrology forum clinical guidelines on the relevance of sperm DNA fragmentation in reproductive medicine Selahittin Çayan, Ala'a Farkouh, Ashok Agarwal, Widi Atmoko, Christine Wyns, Mohamed Arafa, Armand Zini, Rupin Shah, Hiva Alipour, Eric Chung ... [et al.] p. 78-89
Global Andrology Forum (GAF) clinical guidelines on the management of non-obstructive azoospermia : bridging the gap between controversy and consensus Taha Hamoda, Rupin Shah, Taymour Mostafa, Germar-Michael Pinggera, Widi Atmoko, Amarnath Rambhatla, Manaf Al Hashimi, Selahittin Çayan, Giovanni Maria Colpi, Hiva Alipour ... [et al.] p. 90-105
Evaluating the impact of folate on male infertility using Mendelian randomization : a comprehensive analysis Weizhuo Wang, Kang Chen, Yi Yu, Mingwei Chen, Lu Wang, Ying Pang, Meiqi Ren, Hong Zhang, Kai Fu p. 106-117
(A) highly sensitive methylation assay for prostate cancer diagnosis Xingyu Zhong, Zhihao Ming, Haodong He, Yifan Xiong, Shaogang Wang, Qidong Xia p. 118-128
Development of a new diagnostic tool (LUTS/BPH Score) for male lower urinary tract symptoms due to benign prostatic hyperplasia Seong Uk Jeh, Chanho Park, Min Sung Choi, Chang Seok Kang, Dae Hyun Kim, Jae Hwi Choi, See Min Choi, Jeong Seok Hwa, Sung Won Kwon, Sae Cheol Kim ... [et al.] p. 129-135
Single-cell analysis combined with Mendelian randomization identifies genes associated with prostate cancer cells Weizhuo Wang, Kaiyu Lu, Xi Zhang, Kai Wei, Gang Cheng, Zheng Tang, Mingwei Zhan, Caibin Fan, Xu Fu p. 136-149
Robot-assisted versus open radical prostatectomy in the treatment of localized prostate cancer : 3-year results from a prospective cohort study Chang Wook Jeong, Sang Hyun Yoo, Jang Hee Han, Seung-hwan Jeong, Hyeong Dong Yuk, Ja Hyeon Ku, Hyeon Hoe Kim, Cheol Kwak p. 150-160
Does the quality and readability of information related to varicocele obtained from ChatGPT 4.0 remain consistent across different models of inquiry? Zhao Luo, Sung Chul Kam, Ji Yong Kim, Wenhao Hu, Chuan Lin, Hyun Jun Park, Yu Seob Shin p. 161-170
Trends in medical traveling for radical prostatectomy in the era of robotic surgery : a nationwide cohort study in Korea Jinhyung Jeon, Jee Soo Ha, Hye Sun Lee, Soyoung Jeon, Jae Heon Kim, Kang Su Cho p. 171-181
Efficacy and safety of ginseng berry extract (SIRTBERRY™) in treating andropause symptoms : a randomized, double-blind, placebo-controlled clinical trial Sun-Young Park, Yong Seong Lee, In Heo, Soon Chul Myung, Sang Jun Lee, Jin Wook Kim p. 182-193
Characteristics of germline and somatic mutations of DNA repair genes in Korean men with prostate cancer Hakmin Lee, Jin-Nyoung Ho, Sang Hun Song, Jong Jin Oh, Jung Sik Huh, Hak-Min Kim, Kwang Hyun Kim, Sunghan Kim, Seok-Soo Byun p. 194-202
Identification of a novel biallelic CFAP119 variant in an infertile man with asthenoteratozoospermia Jun Ma, Tiechao Ruan, Chuan Jiang, Xiang Wang, Yingteng Zhang, Yunchuan Tian, Xinyao Tang, Yihong Yang, Ying Shen p. 203-215