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국회도서관 홈으로 정보검색 소장정보 검색

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Objective: This study evaluated the antibacterial and antibiofilm activities of the wasabiderived compound 6-(methylsulfinyl)hexyl isothiocyanate (6-MITC) against Streptococcus mutans. Methods: The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of 6-MITC against S. mutans were determined. Antibiofilm activity of 6-MITC was confirmed by human saliva-coated biofilm formation assay. Plates were incubated for 48 h in 1% sucrose-containing saliva medium with bacteria and 6-MITC. After staining with 0.1% crystal violet, the biofilms were dissolved in 20% acetic acid, and absorbance was measured. Results: The MIC and MBC of 6-MITC against S. mutans were 0.125 mg/mL and 0.5 mg/mL, respectively. Biofilm formation was reduced in a concentration-dependent manner by 6-MITC, and, with statistically significant inhibition observed at concentrations ≥0.25 mg/mL (p<0.05). Conclusions: Wasabi-derived 6-MITC exhibits antibacterial and antibiofilm activities against S. mutans. These findings suggest that 6-MITC has potential as a natural candidate for the development of oral hygiene products, antibacterial agents, and infection-control formulations.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
치과위생사의 찔림사고 현황과 관련 요인 = Needlestick and sharps injuries among dental hygienists and influencing factors : preventive behavior awareness and practices : 예방가능행동 인지 및 실천 수준 분석 박연순, 강민경, 이미라, 전수경, 배성숙 p. 219-231
Streptococcus mutans의 성장 및 구강 바이오필름 형성에 대한 wasabi 유래 성분 6-(methylsulfinyl)hexyl isothiocyanate의 효과 = Effects of wasabi-derived 6-(methylsulfinyl)hexyl isothiocyanate on growth and oral biofilm formation by Streptococcus mutans 조하랑, 김기림 p. 233-240
노인의 구강 기능 및 구강건강 관련 삶의 질 개선을 위한 입 체조 프로그램의 효과 = Effects of oral exercise program on improving oral function and oral health-related quality of life in older adults 이다현 p. 241-248
대학생의 생활습관과 구강위생관리습관에 따른 치주질환관련 구강증상경험에 관한 연구 = A study on the experience of oral symptoms related to periodontal disease according to the lifestyle and oral hygiene care habits of university students 정수진 p. 249-256
대학생의 구강건강 위험 예측을 위한 영양지수 활용 가능성 탐색 = Exploring the potential of nutrition quotient (NQ) for predicting oral health risks in university students 조은비, 이형석, 최윤서, 김한나, 한선영 p. 257-269
치위생관리과정에 기반한 치위생결과(Dental Hygiene Outcome) 및 지표 개발 = Development of dental hygiene outcomes and indicators based on the dental hygiene process of care 전혜림, 배수명, 신보미, 윤혜영, 이효진 p. 271-287
뇌졸중 환자에서 통합 구강관리의 효과 = Case-based comparison in stroke patients : impact of integrated oral care and professional hygiene : 전문가 구강위생관리 단독 중재와 증례 비교 김수민, 조은비, 홍지선, 이의연, 김성훈, 한선영 p. 289-297