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Purpose: To examine the association between the risk of obstructive sleep apnea (OSA) and atopic dermatitis (AD), in addition to the dose-response relationship between the risk of OSA and the prevalence of AD.

Methods: This study analyzed data from 15,095 participants aged ≥ 40 years who were part of the 2019–2022 Korea National Health and Nutrition Examination Survey (KNHANES). AD was assessed using self-reported questionnaires, and the risk of OSA was determined using the STOP-BANG score. Demographic distributions were analyzed by using χ2 tests, whereas adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using multivariable logistic regression analysis. The weighted prevalence of AD and 95% CIs were calculated to account for the complex sampling design of KNHANES.

Results: Multivariable logistic regression revealed a significant association between OSA risk and AD, with an OR of 2.159 (95% CI, 1.456–3.202). The weighted prevalence of AD increased with higher OSA risk, from 1.43% in the low-risk group to 1.74% in the intermediate-risk group, and 2.17% in the high-risk group (P value for trend = 0.013).

Conclusions: OSA risk was significantly associated with AD prevalence, having a dose-response relationship. Given the observed associations, incorporating OSA management into clinical strategies may warrant further investigation as a potential avenue for mitigating AD-related risk.

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기사명 저자명 페이지 원문 목차
Update on tree nut and seed allergies : prevalence, clinical characteristics, diagnosis, and management Kyunguk Jeong, Sooyoung Lee p. 672-691
Efficacy of a combination therapy of montelukast and antihistamines in allergic rhinitis : a systematic review and network meta-analysis Ji-Sun Kim, Gulnaz Stybayeva, Se Hwan Hwang p. 692-708
Impact of biologics on nasal symptoms in severe asthmatics : findings from the PRISM study Ji-Su Shim, Hyunkyoung Kim, Jae-Woo Kwon, So-Young Park, Sujeong Kim, Byung-Keun Kim, Young-Hee Nam, Min-Suk Yang, Mi-Ae Kim, Sae-Hoon Kim ... [et al.] p. 709-725
Triglyceride-glucose body mass index predicts asthma exacerbations : a prospective study Fan Gao, Jiahui Lei, Yingjie Guo, Limin Zhao p. 726-741
Siglec-8 as a biomarker for predicting anti-IL-5 response in severe asthma Youngsoo Lee, Hyunkyung Kim, Chae Eun Lee, Byung-Jae Lee, Min-Hye Kim, So-Young Park, Byung Keun Kim, Sae-Hoon Kim, Sang Hoon Kim, Hye-Kyung Park ... [et al.] p. 742-753
Association between obstructive sleep apnea and atopic dermatitis in the Korean adult population : results from the 2019–2022 Korea National Health and Nutrition Examination Survey Jung Min Lee, Wanhyung Lee p. 765-774
Impact of antibiotic exposure on pediatric drug eruption : a nationwide cohort study in Korea Soo Min Jeon, Junwoo Jo, Juhee Ryu, Jin-Won Kwon, Jiung Jeong p. 775-786
Bronchodilator response of TEV/FEV3 and its implications in pediatric asthma Hamin Kim, Yoon Hee Kim, Jae Hwa Jung, Mireu Park, Yun Young Roh, Jong Deok Kim, Min Jung Kim, Yong Ju Lee, Kyung Won Kim, Myung Hyun Sohn, Soo Yeon Kim p. 787-796
(The) prevalence of allergic rhinitis in Korean children : nationwide surveys in the periods 1995-2022 Yong Ju Lee, Hye Mi Jee, Gitae Seo, Chae Hyun Im, Eun Lee, Dong In Suh, Jihyun Kim, You Hoon Jeon, So-Yeon Lee, Hyeon-Jong Yang, Kee-Jae Lee, Woo Kyung Kim, Kangmo Ahn, Hyo-Bin Kim p. 754-764

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