본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

초록보기

Arginine, a conditionally essential amino acid, orchestrates critical metabolic networks in cancer biology and immunotherapy. Abnormalities in arginine metabolism are associated with cancer initiation, progression and immune escape. Polyamines and nitric oxide are the key metabolites with multiple regulatory effects on cancer cell growth and immune cells by driving metabolic reprogramming and promoting immune evasion in cancer cells. Targeting key enzymes and transporters in arginine pathways, along with arginine deprivation therapy, shows promise in preclinical and clinical studies. This review summarizes the regulatory mechanisms of arginine metabolism and evaluates its potential as a therapeutic target in cancer therapy. We specifically discuss the multifaceted roles of arginine and its metabolites in cancer progression, immune cell regulation, and immunotherapy, providing a theoretical foundation for its application in cancer prevention and treatment.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Pathotype-specific expression of granzyme-perforin pathway genes and their association with clinical disease activity in early rheumatoid arthritis and in a randomized clinical trial Francisco G. La Rosa, Larry W. Moreland, Luigi Nibali, Mike Curtis, Kevin D. Deane, Colin Strickland, Jennifer Seifert, Carson Keeter, Dmitri Simberg, Robert I. Scheinman, Rachel Lau, Costantino Pitzalis, Myles J. Lewis, V. Michael Holers, Nirmal K. Banda p. 1-25
Pediatric atopic dermatitis exhibits distinctive patterns in JAK/STAT pathway activation and CD6-ALCAM signaling Soyoung Jeong, Sanghee Shin, Hyun Seung Choi, So-Jung Choi, Sehun Jang, Jeongmin Song, Ji Su Lee, Dong Hun Lee, Hyun Je Kim, Jihyun Kim, Kangmo Ahn p. 1-16
(A) novel approach of T cell receptor classification reveals dynamic interactions amongst diet, microbiota, and host T cells Jisun Jung, Jaeu Yi p. 1-11
Distinct T cell dysregulation reflects disease severity and progression in infantile epileptic spasms syndrome and Lennox-Gastaut syndrome Leechung Chang, Yeo-Jin Jeong, Haeun Chang, Hyeon Deok Sang, Ki-Nam Kwon, Su-Bin Lee, Si-Yoon Kim, You Min Kang, Sungji Ha, Se Hee Kim, Keun-Ah Cheon, Ho-Keun Kwon p. 1-18
Adoptive cellular therapies in pediatric leukemia patients after allogeneic-hematopoietic stem cell transplants Leanne Palichuk, Enoch Tin, Jongbok Lee p. 1-17
Arginine metabolism in cancer biology and immunotherapy DingYuan Bai, YuXuan Zhou, LingJie Jing, Cheng Guo, QuanJun Yang p. 1-17
Enigmatic roles of complement anaphylatoxin signaling in health and disease Anthony Shadid, Kathryn D. Hok, Aleksey Y. Domozhirov, Tingting Weng-Mills, Marie-Françoise Doursout, Nirmal K. Banda, Marcos I. Restrepo, Pooja Shivshankar p. 1-46

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기