본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

초록보기

Purpose: Prematurity and low birth weight increase cardiovascular risk, including hypertension (HTN). However, the combined effect of these factors along with others in the development of HTN is unclear. This study aimed to identify changes in blood pressure in small-for-gestational-age (SGA) patients treated with recombinant human growth hormone (rhGH) by comparison with healthy controls.Methods: We conducted a case-control study with 72 SGA and healthy controls, aged 6 to 16 years. Blood pressure was assessed through office and 24-hour ambulatory blood pressure monitoring (ABPM) recordings (at least 40 measurements including daytime and nighttime), and results were compared between SGA children on rhGH treatment and healthy peers.Results: Forty-six SGA children (41% preterm) on rhGH therapy and 26 healthy controls were enrolled. Despite an average of 5 years of rhGH treatment, no significant difference in HTN frequency was found between groups. However, multiple regression analysis revealed a 0.451 increase in 24-hour diastolic blood pressure (DBP) standard deviation score (SDS) in SGA children on rhGH (P=0.032). Daytime DBP SDS was also increased (0.462; P=0.042). An inverse correlation between weight and gestational age at birth was established. SGA children in the prepubertal stage showed a greater increase in 24-hour DBP SDS than those in the pubertal stage (0.499; P=0.009). Overweight was independently associated with increased 24-hour (0.950; P=0.002) and daytime DBP SDS (1.005; P=0.001).Conclusion: Prolonged rhGH treatment in SGA patients did not increase the risk of HTN. However, ABPM detected subtle changes that highlight the need for careful blood pressure monitoring in overweight prepubertal children.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Unraveling PEX6 : insights into very-long-chain fatty acid levels and peroxisome biogenesis disorders in pediatric populations Najmeh Ahangari, Bita Barazandeh Shirvan, Farah Ashrafzadeh, Ehsan Ghayoor Karimiani, Narges Hashemi, Shima Imannezhad, Hashem Lashgari Kalat, Farnoosh Ebrahimzadeh, Javad Akhondian, Mehran Beiraghi Toosi p. 3-10
Impact of growth hormone therapy on ambulatory blood pressure in small-for-gestational-age children Manuel Vaqueiro Graña, María José González Burgo, Beatriz Calderón Cruz, Nadia Álvarez Expósito, Carmen Lourdes Rey Cordo, Susana Romero Santos, María Carmen Domínguez Grandal, José Luis Chamorro Martín, Evaristo García Martinez, Ana María Goicoechea Castaño, Ana Concheiro Guisán p. 11-19
High prevalence of metabolic comorbidities in Asian children with type 1 diabetes and obesity Jennie Kit-Yee Wong, Joanna Y.L. Tung, Gloria S.W. Pang, Sarah W.Y. Poon p. 20-29
Final adult height in male patients with central precocious puberty after gonadotropin-releasing hormone agonist treatment Kyoung Won Cho, Youn Kyoung Kim, Ji Eun Yoo, Joon Young Kim, Seo Jung Kim, Sujin Kim, Youngha Choi, Kyungchul Song, Eun Byeol Lee, Hyun Wook Chae, Junghwan Suh p. 30-37
Early prediction of transient versus permanent congenital hypothyroidism : a retrospective cohort study Myung Ji Yoo, Ji-Eun Lee, Eun Young Joo, Jisun Park, Young Ju Suh, Su Jin Kim p. 38-44
Outcomes in youth-onset type 2 diabetes during the transition period : glycemic control, microvascular complications, and effects of second-line agents Jeesun Yoo, Yun Jeong Lee, Choong Ho Shin, Young Ah Lee p. 45-54
Correlations among whole-body fat, bone, and biomarkers in boys and girls with obesity : a cross-sectional study Rapheeporn Khwanchuea, Chuchard Punsawad p. 55-65
Preliminary clinical outcomes and adoption of continuous glucose monitoring following reimbursement implementation in patients with type 1 diabetes in Thailand Nichapa Yordsudueam, Nattakarn Numsriskulrat, Worapimon Lerdrassameethad, Pattayarporn Paleekul, Jutipond Jitchana, Nitchakarn Laichuthai, Taninee Sahakitrungruang p. 66-75
Diagnostic implications of the Endocrine Society and American Academy of Pediatrics guidelines on blood pressure : associations with sex, blood pressure components, and metabolic syndrome in Korean adolescents In-Hyuk Chung, Yong Hee Hong, Sochung Chung p. 76-84

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기