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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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Purpose: This study investigated the associations between early-life perinatal risk factors, postnatal weight-growth trajectories, and pulmonary function at early school age in children born very preterm.

Methods: This longitudinal cohort study included 72 children born before 30 weeks of gestation or with a birth weight below 1,250 g who completed spirometry at 6–7 years of age. Multiple linear and logistic regression analyses (n=69) were performed to examine the associations of gestational age, sex, birth weight z-score, antenatal corticosteroid exposure, Jensen 2019 bronchopulmonary dysplasia severity grade as an adjustment covariate, and two postnatal weight z-score change variables (birth to 36 weeks postmenstrual age [PMA], and 36 weeks PMA to the time of pulmonary function test [PFT]) with forced expiratory volume in 1 second (FEV₁) z-score and FEV₁/forced vital capacity (FVC) z-score.

Results: Lower gestational age (β=0.18, P=0.026), male sex (β=−0.57, P=0.038), lower birth weight z-score (β=0.48, P<0.001), and smaller post-discharge weight gain (β= 0.19, P=0.048) were independently associated with lower FEV₁ z-score. For FEV₁/FVC z-score, higher birth weight z-score (β=−0.47, P=0.005), greater in-hospital weight gain PMA (β=−0.63, P=0.009), and higher Jensen BPD grade (β=−0.52, P=0.036) were inversely associated with FEV₁/FVC in multiple linear regression. In logistic regression, higher birth weight z-score (odds ratio [OR], 2.39, P=0.007) and greater in-hospital weight gain (OR, 3.97, P=0.002) were associated with higher odds of FEV₁/FVC.

Conclusion: Lower gestational age, male sex, lower birth weight z-score, and smaller post-discharge weight gain were independently associated with lower school-age FEV₁. In contrast, higher birth weight z-score and greater early postnatal weight gain from birth to 36 weeks PMA were associated with lower FEV₁/FVC, consistent with a dysanaptic growth pattern.

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기사명 저자명 페이지 원문 목차
Clinical significance and treatment strategies of patent ductus arteriosus in preterm infants : an evidence-based approach to decision-making Soon Min Lee, Byong Sop Lee, Mi Young Han, Hyun Ho Kim, Teahyen Cha, Seung Hyun Kim, Ju Sun Heo, Eui Kyung Choi, Yeong Myong Yoo, Kee Hyun Cho, Byoungkook Lee, Eun Song Song, Se In Sung, Yun Sil Chang p. 4-17
미숙아 동맥관개존증의 임상적 의미와 치료 전략 : 대한신생아학회 권고문 이순민, 이병섭, 한미영, 김현호, 차태현, 김승현, 허주선, 최의경, 유영명, 조기현, 이병국, 송은송, 성세인, 장윤실 p. 18-29
Perinatal factors and postnatal growth trajectories as determinants of school-age pulmonary function in preterm infants Jihye Yoon, Seung Han Shin, Baek Sup Shin, Ji Soo Park, Dong In Suh, Dabin Kim, Gyeong Eun Yeom, Seh Hyun Kim, Ju Sun Heo, Ee-Kyung Kim, Han Suk Kim p. 30-38, [1-3]
Current infrastructure for surgical management including patent ductus arteriosus ligation in Korean neonatal intensive care units : a nationwide survey Sung-Hoon Chung, Jong-Hee Hwang, Survey and Statistics Committee of the Korean Society of Neonatology p. 39-48
Establishing cohort-specific reference values for terme-quivalent age brain magnetic resonance imaging abnormality scores in a Korean cohort Dabin Kim, Hae Min Kang, Ji Hye Yoon, Jieun Jeong, Gyeong Eun Yeom, Baek Sup Shin, Seh Hyun Kim, Ju Sun Heo, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim p. 49-55
Real-world outcomes of treprostinil treatment in very-low-birth-weight infants with pulmonary hypertension : a nationwide cohort study Jieun Jeong, Haemin Kang, Ho Jung Choi, Sohee Oh, Jin A Lee p. 56-65, [1]
Language outcomes in moderate-to-late preterm infants at 2 years of corrected age Sung Hee Lee, Ju Hyun Jin, Shin Won Yoon p. 66-73
Neurodevelopmental outcomes at 1 year of age after extubation failure in very preterm infants : a single-center cohort study Ju Hee An, Kyung Hee Park, Mun Hui Jeong, Seong Hee Jeong, NaRae Lee, Shin Yun Byun, Su Jeong Park p. 74-81
Short- and long-term morbidities in preterm infants with necrotizing enterocolitis or spontaneous intestinal perforation Jung In Kang, Sangjun Park, So-Yeon Shim, Joo Yun Yang, Young Min Youn, Ye Jin Han, Do Kyung Lee, Hyun Kyung Bae, Soeun Park, Jin A Sohn p. 82-92, [1]
Posthemorrhagic ventricular dilatation after grade Ⅱ–Ⅳ intraventricular hemorrhage in neonates : a single-center cohort study Hye Jin Park, Sang-Yoon Lee, Hyeong-Taek Woo, Ji Sook Kim p. 93-104, [1-3]
Infants with sacral dimples : clinical outcomes and usefulness of ultrasonography Sung Hee Lee, Ju Hyun Jin, Shin Won Yoon p. 105-111
Molybdenum cofactor deficiency type B mimicking hypoxic-ischemic encephalopathy in a neonate : the first genetically confirmed case in Korea Soowan Shin, Baek Sup Shin, Seung Han Shin, Ee-Kyung Kim, Han-Suk Kim, Jung Min Ko, Jong-Hee Chae, Soo Yeon Kim, Seung Bok Lee p. 112-116

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