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Objectives: Evidence regarding the association between obstructive sleep apnea (OSA) and mortality following acute myocardial infarction (MI) remains inconsistent. This study aimed to clarify this relationship through a systematic review and meta-analysis.Methods: A comprehensive search of six international databases (PubMed, Scopus, Web of Science, ScienceDirect, Google Scholar, and Embase) was conducted on November 11, 2024, without time restrictions. Statistical analyses included a random-effects model stratified by adjusted odds ratio (aOR) and adjusted hazard ratio (aHR). Short-term mortality was defined as in-hospital or ≤30-day mortality, whereas long-term mortality referred to outcomes assessed after a minimum follow-up of 3 months. Data synthesis was performed using Comprehensive Meta-Analysis software (Version 2).Results: Six studies, including a total of 7,032,232 individuals, showed that short-term post–acute MI mortality was lower among individuals with OSA (aOR=0.67; 95% confidence interval [CI] 0.61–0.74). In contrast, pooled analysis of seven additional studies (n=12,545) reporting aHR indicated that OSA was associated with a 53% increased risk of long-term mortality (aHR=1.53; 95% CI 1.22–1.92). Egger’s test showed no evidence of publication bias.Conclusions: OSA did not show a significant association with increased short-term post-MI mortality in aOR-based analyses but was linked to a higher risk of long-term mortality in aHR-based analyses. This discrepancy may reflect methodological differences, including the absence of time-to-event modeling in aOR and the greater sensitivity of aHR, as well as variations in study design and follow-up duration. Further well-designed studies are required to confirm these findings.

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Association between obstructive sleep apnea and post-myocardial infarction all-cause mortality : a systematic review and meta-analysis Nader Salari, Masoud Mohammadi, Seyed Hamidreza Hashemian, Avijeh Rahimi, Seyed Rasoul Mousavi, Azad Maroufi, Habibolah Khazaie, Ritwick Agrawal, Robert Thomas, Amir Sharafkhaneh p. 1-9
Light control-based interventions to improve symptoms after night shifts in nurses : a review Adrián Poblano, Rafael Santana-Miranda p. 10-19
Clinical characteristics and comorbidities of obstructive sleep apnea patients : insights from sleep breathing disorders Cairo University Registry (2022–2024) Safy Zahid Kaddah, Irene Mohamed Sabry, Samah Selim Abd El Naiem, Eman Kamal Ibrahim, Naglaa Bakry Ahmed, Eman Abdelsalam, Naglaa Mostafa Mohammed, Afnan Nabil Fathi, Asmaa Mohammed Alkawas, Sarah Mohamed Farrag, Rana Kamal El Said, Hamza Saeed Abdelaziz p. 20-27
(An) “eye-closing” experience : a rare case of hypersomnia occurring two years after COVID-19 Mariam Mirza, Celina R. Bou Jaoude, Efeose Airewele, Hrayr Attarian p. 28-31
Shortening Kleine-Levin syndrome episodes with oral steroids : insights from two cases Noor Hajjaj, Danielle Bradshaw, Ty Carter, Mac Manuel, Erin Hauck, Dwayne Henry, Yash Shah p. 32-36

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