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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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The fruit of Morus alba L. is rich in bioactive compounds with antioxidant and anti-inflammatory properties; however, the biological effects of its fermented extract have not been fully elucidated. This study investigated the effects of fermentation on the antioxidant and anti-inflammatory activities of mulberry fruit extract (ME). Mulberry fruit was fermented using Lactiplantibacillus plantarum (LP), Lacticaseibacillus casei (LC), and Bifidobacterium bifidum (BB), and the resulting fermented extract (MFE) was compared with non-fermented extract. Cell viability was evaluated by MTT assay in LPS-stimulated RAW 264.7 macrophages, and neither ME nor MFE exhibited cytotoxicity. Antioxidant activity was assessed using the DPPH radical scavenging assay, in which MFE showed higher antioxidant capacity than ME. To evaluate anti-inflammatory activity, nitric oxide (NO) production was measured in LPS-stimulated RAW 264.7 cells. MFE significantly and dose-dependently suppressed NO production compared with ME. These results indicate that fermentation enhances the antioxidant and anti-inflammatory activities of mulberry fruit extract and suggests its potential as a value-added functional plant resource.

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Anti-inflammatory effects of fermented mulberry fruit on lipopolysaccharide (LPS)-induced inflammation in RAW 264.7 cells Sungsun Kim, SaHaeng Kang, Ju-Ryoun So, Hoonsung Choi, JeongHyang Park, DongKeun Kim, Ji Hae Lee, Yeong Hee Cho, JongSik Jin p. 121-131
Dual anti-neuroinflammatory and neuroprotective actions of a wild-simulated ginseng aerial-underground blend in SIM-A9 microglia and SH-SY5Y neurons Hyeok Jin Choi, Yurry Um, Jeong Won Choi, So Jung Park, Gyeong Eun Im, Yeong-Bae Yun, Sang Hun Lee, Jin Boo Jeong p. 132-146
Anti-neuroinflammatory and neuroprotective effects of 11S,17S-DiHDHA in SIM-A9 and SH-SY5Y cells Jin Boo Jeong p. 147-161
In vitro callus induction from root tip and bulb meristem explants of two ornamental allium species native to Korea Jeong Min Kim, Chung Hwa Park, Ji Young Jung, Chung Ho Ko, Bo-Kook Jang p. 162-169
Effects of different shading levels on growth and physiological responses of Neolitsea sericea (Blume) Koidz. seedlings Ji Seon Lee, Eun-Young Yim p. 170-177

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