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[표지] 1

연구결과 요약문 3

목차 4

1. 연구개발과제의 개요 5

2. 연구수행내용 및 연구결과 5

1. Molecular Insights into the Interaction of RONS and Thieno[3,2-c]pyran Analogs with SIRT6/COX-2: A Molecular Dynamics Study (Scientific Reports. 2018; 8(1):4777. (corresponding author)). 5

2. Insight Into the Molecular Dynamic Simulation Studies of Reactive Oxygen Species in Native Skin Membrane (Frontiers in Pharmacology. 2018; 9:644. (corresponding author)) 6

3. Insight from Molecular dynamic simulation of reactive oxygen species in oxidized skin membrane (Scientific Reports. 2018, 5;8(1):13271 (corresponding author)). 7

4. Molecular dynamic simulations of oxidized skin lipid bilayer and permeability of reactive oxygen species (Scientific Reports. 9(1):4496 (corresponding author)) 7

5. Synthesis, Bioevaluation, Structure-Activity Relationship and Docking Studies of Natural Product Inspired (Z)-3-benzylideneisobenzofuran-1(3H)-ones as Highly Potent antioxidants and Antiplatelet agents (Scientific Reports. 2020, 10:2307 (corresponding author)) 8

6. Atomic-scale modeling of the effect of lipid peroxidation on the permeability of reactive species (J Biomol Struct Dyn. 2020; 5;1-11)) 9

7. Ligand-based pharmacophore modeling and docking studies on vitamin D receptor inhibitors (Journal of Cellular Biochemistry. 2020; 1-14 (corresponding author)) 10

7. Electric-field-induced Electroporation and Permeation of Reactive Oxygen Species Across a Skin Membrane (J Biomol Struct Dyn. 2020; 2;1-11 (Corresponding author)) 10

8. Cold atmospheric plasma generated reactive species aided inhibitory effects on human melanoma cells: an in vitro and in silico study (Scientific Reports. 2020; 25;10(1):3396. (Corresponding author)) 11

9. Computational Modeling on Aquaporin-3 as Skin Cancer Target: A Virtual Screening Study (Frontiers in Chemistry. 2020; 15;8:250 (Corresponding author)) 12

3. 연구개발결과의 중요성 13

4. 참고문헌 13

5. 연구성과 14

주관연구책임자 대표적 연구실적 17

붙임 : 주관연구책임자(공동연구원 포함) 대표적 논문·특허실적 요약문 19

대표적 연구실적 사본 23

별첨 4

〈별첨1〉 자체평가 의견서[내용없음] 4

〈별첨2〉 연구개발성과 활용계획서[내용없음] 4